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Empiric Regimens Flashcards

1
Q

Empiric Regimens
Community-acquired pneumonia
Common pathogens

A 
S. pneumoniae 
H. influenzae 
Mycoplasma pneumoniae
Chlamydophila pneumoniae 
Legionella pneumophila
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2
Q 
Empiric Regimens
Community-acquired pneumonia
Outpatient, otherwise healthy
No recent antibiotic exposure 
Treatment
A 
Doxycycline 
or 
Azithromycin 
or
Clarithromycin
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3
Q 
Empiric Regimens
Community-acquired pneumonia
Outpatient
Comorbidities and/or recent antibiotic exposure 
Treatment
A

Amoxicillin or Amox/Clav
or
Cefuroxime Plus
Azithromycin or Clarithromycin

OR

Levo/Moxi/Gemifloxacin

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4
Q

Empiric Regimens
Community-acquired pneumonia
Inpatient; non-ICU
Treatment

A 
Ceftriaxone 
or
Cefotaxime 
or 
Ampicillin 
or
Ertapenem
Plus
Azithromycin
or
Clarithromycin 
or
Doxycycline

OR

Levo/Moxifloxacin

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5
Q

Empiric Regimens
Community-acquired pneumonia
Inpatient, ICU
Treatment

A 
Ceftriaxone 
or
Cefotaxime 
or 
Amp/Sulb 
Plus
Azithromycin 
or
Levo/Moxifloxacin
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6
Q

Empiric Regimens
Healthcare-associated pneumonia
Early onset (within 5 days of hospitalization) and no recent antibiotic exposure
Common pathogens

A 
S. pneumoniae
H. influenzae 
MSSA
E. coli
Klebsiella pneumoniae
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7
Q

Empiric Regimens
Healthcare-associated pneumonia
Early onset (within 5 days of hospitalization) and no recent antibiotic exposure
Treatment

A 
Ceftriaxone 
or
Amp/Sulb 
or
Ertapenem 
or
Levo/Moxifloxacin
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8
Q

Empiric Regimens
Healthcare-associated pneumonia
Late onset (after 5 days of hospitalization) and/or recent antibiotic exposure
Common pathogens

A 
MRSA
Enterobacter sp 
Proteus sp 
Serratia sp 
P. aeruginosa

Plus

S. pneumoniae
H. influenzae 
MSSA
E. coli
Klebsiella pneumoniae
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9
Q

Empiric Regimens
Healthcare-associated pneumonia
Late onset (after 5 days of hospitalization) and/or recent antibiotic exposure
Treatment

A 
Cefepime
or
Ceftazidime 
or 
Imipenem 
Or
Meropenem 
or
Pip/Tazo 
or
Aztreonam 
Plus
Cipro/Levofloxacin
or
Gent/Tobra 
or
Amikacin 
Plus
Vancomycin 
or
Linezolid
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10
Q

Otitis Media

Common Pathogens

A

Viruses
S. pneumoniae
H. influenzae
Moraxaella catarrhalis

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11
Q

Otitis Media
Mild-moderate otalgia with temperature less than 39C
Treatment

A 
Amoxicillin
or
Cefuroxime
or 
Cefpodoxime 
or
Azithromycin
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12
Q

Otitis Media
Severe otalgia and/or temperature greater than 39C
Treatment

A

Amox/Clav
or
Ceftriaxone

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13
Q

Pharyngitis

Common pathogens

A

Viruses

S. pyogenes

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14
Q

Pharyngitis
Documented or high risk for S. pyogenes
Treatment

A 
Penicillin VK
or
Cephalexin 
or
Azithromycin
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15
Q

Urinary Tract Infection
Uncomplicated community acquired lower UTI in healthy women less than 50 yo
and
Community acquired complicated UTI or pyelonephritis
Common pathogens

A 
E. coli 
Proteus sp 
K. pneumoniae 
S. saphrophyticus 
Enterococcus sp
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16
Q

Urinary Tract Infection
Nosocomial complicated UTI or pyelonephritis
Common pathogens

A

Enterobacter sp
P. aeruginosa

Plus

E. coli 
Proteus sp 
K. pneumoniae 
S. saphrophyticus 
Enterococcus sp
17
Q

Urinary Tract Infection
Uncomplicated community acquired lower UTI in healthy women less than 50 yo
Treatment

A 
T/S
or
Nitrofurantoin 
or
Fosfomycin 
or
Cipro/Levofloxacin
18
Q

Urinary Tract Infection
Community acquired complicated UTI or pyelonephritis
Treatment

A 
Cipro/Levofloxacin 
or
Ceftriaxone
or 
Ertapenem
19
Q

Urinary Tract Infection
Nosocomial complicated UTI or pyelonephritis
Treatment

A 
Ceftazidime 
or
Pip/Tazo
or 
Cefepime
or 
Mero/Imipenem
20
Q

Skin/soft tissue infections
(General)
Common pathogens

A

Strep pyogenes

Staph aureus

21
Q

Skin/soft tissue infections
Diabetic foot infection (mod-severe)
Common pathogens

A 
E. coli 
Proteus sp 
K. pneumoniae 
Bacteroides fragilis
Enterococcus sp 
P. aeruginosa

Plus
S. pyogenes
S. aureus

22
Q

Skin/soft tissue infections
(General)
Low risk for MRSA
Treatment

A 
Cefazolin 
or
Nafcillin 
or 
Cephalexin 
or
Dicloxacillin
23
Q

Skin/soft tissue infections
(General)
High risk for MRSA
Treatment

A 
Vancomycin 
or
Linezolid 
or
Clindamycin

OR

Cephalexin
or
Dicloxacillin 
Plus
Doxycycline 
or
T/S
24
Q

Skin/soft tissue infections
Diabetic foot infection (mod-severe)
Treatment

A 
Ceftriaxone 
or
Amp/Sulb 
or 
Pip/Tazo 
or
Ertapenem

OR

Levo/Ciprofloxacin
Plus
Clindamycin

All with or without Vancomycin

25
Intra-abdominal infections Community-acquired, mild-mod severity Common pathogens
``` E. coli Proteus sp K. pneumoniae B. fragilis Enterococcus sp Viridans strep ```
26
``` Intra-abdominal infections Community-acquired, high severity or high risk patient OR Nosocomial (any severity or patient) Common pathogens ```
P. aeruginosa Enterobacter sp Serratia sp Plus ``` E. coli Proteus sp K. pneumoniae B. fragilis Enterococcus sp Viridans strep ```
27
Intra-abdominal infections Community-acquired, mild-mod severity Treatment
``` Ertapenem or Moxifloxacin or Tigecycline ``` OR ``` Cefazolin or Ceftriaxone or Levo/Ciprofloxacin Plus Metronidazole ```
28
``` Intra-abdominal infections Community-acquired, high severity or high risk patient OR Nosocomial (any severity or patient) Treatment ```
``` Pip/Tazo or Imipenem or Meropenem ``` OR ``` Ceftazidime or Cefepime Plus Metronidazole ``` All with or without Vancomycin
29
Community-acquired meningitis Otherwise healthy, 2-50 yo Common pathogens
S. pneumoniae | Neisseria meningitidis
30
Community-acquired meningitis Greater than 50 yo or immunocompromised Common pathogens
Listeria monocytogenes Plus S. pneumoniae Neisseria meningitidis
31
Community-acquired meningitis Otherwise healthy, 2-50 yo Treatment
Ceftriaxone Plus Vancomycin
32
Community-acquired meningitis Greater than 50 yo or immunocompromised Treatment
``` Ceftriaxone Plus Vancomycin Plus Ampicillin ```
33
Healthcare associated infectious diarrhea Common pathogens
Clostridium difficile
34
Healthcare associated infectious diarrhea Mild-mod infection Treatment
Metronidazole (oral)
35
Healthcare associated infectious diarrhea Severe infection Treatment
Vancomycin (oral) or Fidaxomicin
36
Healthcare associated infectious diarrhea Severe complicated infection (eg., ileus) Treatment
Vancomycin (oral) Plus Metronidazole (IV)
37
Community-acquired infectious diarrhea | Common pathogens
``` Shigella Salmonella E. coli Campylobacter C. difficile (uncommon) ```
38
Community-acquired infectious diarrhea | Treatment (if antibiotic therapy necessary)
FQ or T/S

Antibiotics (63 decks)

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