emerging diseases Flashcards
emerging infections are most likely what type of microbe? why?
RNA virus; due to high mutation rate related to lack of proofreading
what animal in implicated in many emerging infections?
bats
strain of ebola with highest associated mortality
Zaire
proposed ebola reservoirs
bats
strain of ebola only in non-human primates
reston
ebola transmission to humans from primates-
infected bush meat
ebola transmission from humans to humans
contact with body fluids (including sweat, breast milk, sperm)
people with ebola are infectious once they develop-
fever
long term sequelae of ebola (2)
joint pain
blindness
human-human transmission is considered to have been stopped if there are no new cases in what period of time?
2 incubation periods (for ebola= 42 days)
3 medical treatments for ebola
zmapp (mab)
serum from recovered puts (antibodies)
brincidofovir
how are people returning to the country from endemic areas monitored for the development of ebola?
quarantine and checking of temp for fever BID x 21 days
2 animals implicated in MERS
camels and bats
MERS symptoms
severe respiratory symptoms
people effected worst by MERS
those with pre-existing chronic medical conditions
how can you test for MERS?
PCR of blood or stool
care for pt with MERS
supportive care, airborne precautions
leading cause of acute febrile illness in US travelers returning from Caribbean, south america and asia
Dengue fever
vector for dengue fever (2)
classic- Aedes egyptei
in US- Aedes albopictus (tiger mosquito)
symptoms of chikungunya
similar to dengue fever, but not as severe and no hemorrhagic fever (arthritis, fever, myalgia, rash, conjunctivitis)
virus that had outbreak in the US last year, affecting children with respiratory disease the most
enterovirus D68
viral hemorrhagic fevers are typically all-
RNA viruses
natural host/diseases associated with arenavirus
natural hosts- rats, mice
LCMV, Lassa virus, Lujo virus
natural host/diseases associated with bunyavirus
natural hosts- arthropods, rats
Crimean-Congo fever, Rift valley fever, Hantavirus