Emergency Medicine Flashcards
causes of shock?
CHOD
Cardiogenic:
MI, arrhythmia
hypovolaemic:
haemorrhage- internal/ external
endocrine- addisionian crisis, DKA
excess loss- burns, diarrhoea, vomiting
third-spacing- pancreatitis
obstructive:
PE, tension pneumothorax, cardiac tamponade
distributive:
sepsis, anaphylaxis, neurogenic
mx of shocked patient?
if ECG unrecordable, mx as a cardiac arrest
->
ABCDE approach
->
raise foot of bed (unless cardiogenic)
->
IV access: 2 wide bore cannula in each Antecubital fossa
->
fast infusion of crystalloid to raise BP (unless cardiogenic)
initial monitoring of a shocked patient?
catheter to measure urine output
(>30ml/hr)
arterial line- monitor blood pressure directly and in real-time
central venous pressure line-
blood pressure in the venae cavae, near the right atrium of the heart. CVP reflects the amount of blood returning to the heart and the ability of the heart to pump the blood back into the arterial system.
what is anaphylactic shock?
type 1 IgE mediated hypersensitivity reaction
TH2 driven IgE production following primary allergen exposure
re exposure -> biphasic inflammatory response
early phase: mast cell degranulation -> histamine release
late phase: amplify and sustain the initial response
presentation of anaphylactic shock?
skin: urticaria, itching, oedema
breathing: wheeze, laryngeal obstruction, cyanosis
GI: D+V, abdo pain
sweating
CVS: tachycardia, hypotension
mx of anaphylactic shock
secure airway: give 100% O2
- consider intubation if respiratory obstruction
elevate the feet
IM adrenaline 0.5ml of 1:1000 (0.5mg)
- repeat every 5 min if needed
Secure IV access: IV 0.9% saline (500ml over 15 min)
IV 10mg chlorphenamine
IV 200mg hydrocortisone
Salbutamol nebs if wheeze
- 5mg salbutamol + 0.5mg ipratropium
discharge advice for anaphylaxis patient
teach adrenaline self-injection and ensure pt has at least 2 epipens
advise wearing medic alert bracelet
advice re recognition and avoidance
arrange outpatient followup: skin prick tests, RAST to identify antigens
what is the definition of a supraventricular tachycardia?
rate > 100 beats/min
QRS width < 120 ms
start from atria/ AV node
types of SVT
Sinus tachycardia
Atrial:
AF, Atrial flutter, atrial tachycardia
AV nodal re-entry tachycardia (AVNRT)
AV re-entry tachycardia (AVRT): e.g. Wolff-Parkinson-White
What is AVRT?
Atrioventricular re-entrant tachycardia
a type of SVT
e.g. WPW
electrical signal passes in the normal manner from the AV node into the ventricles
the electrical impulse pathologically passes back into the atria via the accessory pathway (e.g. bundle of Kent), causing atrial contraction, and returns to the AV node to complete the reentrant circuit
-> may cause heart to beat faster
SVT Mx
if patient is compromised?
sedate + DC cardioversion
otherwise ID rhythm and treat accordingly
pt compromised
ie. MI, syncope, hypotension (shock), heart failure
SVT Mx?
ID rhythm ?
irregular -> treat as AF
regular?
SVT = Start with Vagal Treatment
(e.g. carotid sinus massage, valsalva)
if unsuccessful,
ABCD
adenosine while recording continuous rhythm strip
-> 6mg IV bolus, then 12mg, 12mg
then
choose from:
Beta Blockers: e.g. atenolol
CCB e.g. Verapamil
Digoxin
Amiodarone
SVT mx if all medical treatment fails?
DC cardioversion
SVT mx if adverse signs develop
ie. BP <90, heart failure, decreased consciousness, HR> 200?
Sedation
Synchronised Cardioversion
then
Amiodarone: 300 mg over 20-60 min
then 900mg over next 23 h
what are vagal manoeuvres meant to do in SVT mx?
decreases HR by stimulating vagus nerve
transiently increases AV block and may unmask underlying atrial rhythm
Giving adenosine in SVT mx?
what would it do
transient AV block -> unmasking atrial rhythm
cardioverts AVRT/AVNRT to sinus rhythm
Mode of action of adenosine?
temporary AV node block
Side effects of adenosine?
transient chest tightness, dyspnoea, flushing, headache
relative contraindications of adenosine?
asthma,
2nd/3rd degree heart block
in what type of SVT will you avoid the usual treatment pathway?
ie. Adenosine, CCB, BB
WPW
hx of WPW or AF/flutter with WPW
-> may lead to VF
Use amiodarone or flecainide
mx of AF?
onset <48h consider cardioversion w amiodarone or DC shock
Rate control: BB e.g. metoprolol or digoxin
Anticoagulation with heparin/ warfarin
prophylaxis of SVTs?
BB
AVRT: Flecainide
AVNRT: verapamil
Definition of broad complex tachycardias?
rate > 100bpm
QRS width >120 ms
types of broad complex tachycardias?
VT
Torsades de pointes
SVT w BBB
Causes of VT?
IM QVICK
Infarction (esp w ventricular aneurysm)
Myocarditis
QT interval prolonged
Valve abnormality: mitral prolapse, AS
Iatrogenic: digoxin, antiarrhythmics
Cardiomyopathy esp dilated
K low, low Mg, low O2, acidosis
Mx of broad complex tachycardia if pt is compromised?
ie. BP <90
Heart failure
chest pain (MI)
decreased consciousness / syncope
HR >150
Sedation
->
Synchronised cardioversion
(200->300->360)
->
Amiodarone:
300mg over 20-60 min
900 mg over next 23h
Mx of stable VT?
after O2 + IV access
Correct electrolyte problems:
ie. Low K+: max 60 mM KCl @ 20mmol/h
Low Mg2+: 4ml 50% MgSo4 in 30 min
mx of stable VT
if no electrolyte problems?
assess rhythm
regular ie. VT:
amiodarone
or lignocaine 50mg over 2min
irregular:
usually AF w BBB: flecainide/ amiodarone
or Torsades de pointes: MgSO4 2g IV over 10 min
mx of stable VT if medical treatment failed?
synchronised cardioversion
mx of Torsades de pointes?
MgSO4 2g IV over 10 min
Mx of recurrent/ paroxysmal VT?
Medical:
Amiodarone
BB
Implantable cardiac defibrillator
Acute Mx of STEMI?
12 lead ECG
O2 2-4L: aim for SpO2 94-98%
IV access: bloods for troponin, FBC, U+E, glucose, lipids
brief assessment: hx of CVD/ RFs, thrombolysis CIs, ABCDE
anti-platelets:
aspirin 300mg PO (then 75mg/d) + clopidogrel 300mg PO (then 75mg/d)
analgesia: morphine 5-10mg IV, metoclopramide 10mg IV
anti-ischaemia: GTN 2 puffs or 1 tablet sublingual, BB atenolol 5mg IV (CI asthma, LVF)
DVT prophylaxis: enoxaparin 40mg SC OD
admit to CCU for monitoring: arrhythmias, continue meds except CCBs
-> consider primary PCI / thrombolysis
when is Percutaneous coronary intervention inndicated in STEMI?
usually tx of choice if <12h
angioplasty and stenting
complications of primary PCI for STEMI?
bleeding
emboli
arrhythmia
if high risk patient
e.g. delayed PCI, Diabetes mellitus, complex procedure,
what medication is given alongside primary PCI for STEMI
GpIIb/IIIa antagonist
eg. tirofiban
DVT prophylaxis in STEMI mx
if pt is not receiving any reperfusion therapy?
if pt is receiving PCI?
not receiving any form of reperfusion therapy:
fondaparinux
otherwise:
enoxaparin
ECG criteria for thrombolysis?
ST elevation > 1mm in 2+ limbs or >2mm in 2+ chest leads
new LBBB
posterior: deep ST depression and tall R waves in V1- V3
when is thrombolysis for STEMI contraindicated?
beyond 24h of onset
AGAINST
aortic dissection
gi bleeding
allergic reaction previously
iatrogenic: major surgery <14d prior
neuro: cerebral neoplasm/ CVA hx
severe HTN (200/120)
trauma inc CPR
what are the agents used in thrombolysis in STEMI?
1st line:
streptokinase
alteplase
tenecteplase
complications of thrombolysis
bleeding
stroke
arrhythmia
allergic reaction
continuing therapy (long term) for STEMI?
lifestyle advice
Stop smoking
Diet: oily fish, fruit, veg, ↓ sat fats
Exercise: 30min OD
Work: return in 2mo
Sex: avoid for 1mo
Driving :avoid for 1mo
continuing therapy (long term) for STEMI?
medications
address risk factors
ACEi: start within 24h of MI (e.g. lisinopril 2.5mg)
BB: e.g. bisoprolol 1.25 mg OD (or CCB)
Cardiac rehabilitation: group exercise and info/ heart manual
DVT prophylaxis until fully mobile
(cont for 3 mo if large anterior MI)
Statin: regardless of basal lipids e.g. atorvastatin 80mg
Continue clopidogrel for 1mo following STEMI
Continue aspirin indefinitely.
NSTEMI mx?
exactly same as STEMI
assess CV risk
if low risk: no further pain, flat or inverted T waves or normal ECG, -ve troponins
may discharge + outpatient tests: angio, perfusion scan, stress echo
intermediate to high risk: persistent/ recurrent ischaemia, ST depression, + trops
GpIIb/IIIa antagonist - tirofiban
Angiography with PCI within 96 h
clopidogrel 75mg/d for one year + aspirin indefinitely
causes of severe pulmonary oedema?
cardiogenic:
MI, arrhythmia, fluid overload: renal/ iatrogenic
non-cardiogenic:
ARDS: sepsis, post op, trauma
upper airway obstruction
neurogenic- head injury
symptoms of severe pulmonary oedema
SOB
orthopnoea
pink frothy sputum
signs of severe pulmonary oedema
Distressed, pale, sweaty, cyanosed
↑HR, ↑RR
↑JVP
S3 / gallop rhythm
Bibasal creps
Pleural effusions
Wheeze (cardiac asthma)
monitoring of severe pulmonary oedema?
BP
HR, RR
JVP
urine output
ABG
Mx of severe pulmonary oedema
Sit pt up
give O2 15L via non-rebreather mask for SpO2 to be 94-98%
IV access + monitor ECG
- take bloods for FBC, U+E, troponin, BNP, ABG
- tx any arrhythmias
IV furosemide 40-80mg (if pt on oral diuretics, use double dose)
IV GTN 0.5mg / hr (only if systolic BP >90)
Consider slow IV diamorphine 2.5-5mg + metoclopramide (for severe chest pain/ distress)
if SBP <100: tx as cardiogenic shock
(ie. consider inotropes)
indications for diamorphine in acute pulmonary oedema?
analgesia and sedation may be appropriate where the patient is in pain or distressed - eg, diamorphine 2.5-5 mg intravenously slowly
+ pulmonary venodilators -> decreases preload -> reduces SOB
opiates should not be given to patients with acute decompensated heart failure, or if drowsy, exhausted or hypotensive.
not used routinely
mx of acute pulmonary oedema if poor response to nitrates and furosemide?
Consider continuous positive airway pressure CPAP or NIV
if acidotic or poor response
! must discuss w senior
consider:
Referral to senior medical staff and intensive care for consideration of IV inotropes or invasive ventilation.
what is CPAP?
CPAP increases intrathoracic pressure, which reduces preload by decreasing venous return.
CPAP lowers afterload by increasing the pressure gradient between the left ventricle and the extrathoracic arteries, which may contribute to the associated increase in stroke volume.
Ix of severe acute pulmonary oedema?
ABG: to assess type and severity of resp failure + associated biochemical changes
CXR: ABCDE
ECG: MI, arrhythmias, pulsus alternans
consider echo
what CXR findings are assoc w Heart failure?
ABCDE
Alveolar oedema (bat’s wings)
kerley B lines (interstitial oedema)
Cardiomegaly
Dilated prominent upper lobe vessels
Effusion (pleural)
long-term mx of stable pt with pulmonary oedema?
daily weights
DVT prophylaxis
repeat CXR
change to oral furosemide/ bumetanide
ACEi + BB if heart failure
consider spironolactone
consider digoxin +/- warfarin (esp in AF)
definition of cardiogenic shock?
inadequate tissue perfusion (and oxygenation) to suit body’s metabolic needs primarily due to cardiac dysfunction
causes of cardiogenic shock?
MI
HyperK (+ other electrolytes)
Endocarditis
Aortic dissection
Rhythm disturbance
Tamponade
Obstructive: tension pneumothorax, massive PE
presentation of cardiogenic shock
unwell: cyanosed, pale, distressed
cold clammy peripheries
high RR, HR
pulmonary oedema
signs of cardiac tamponade?
Beck’s triad: low BP, raised JVP, muffled heart sounds
pulsus paradoxus: (pulse fades on inspiration)
Mx of cardiac tamponade?
pericardiocentesis
(preferably under US guidance)
what is Kussmaul’s sign?
assoc with constrictive pericarditis
raised JVP on inspiration
what is Beck’s triad?
assoc w Cardiac tamponade
low BP, raised JVP, muffled heart sounds
Ix of Cardiac tamponade?
echo: diagnostic
CXR: globular heart
mx of cardiogenic shock?
ABCDE approach
O2
monitor ECG
diamorphine + metoclopramide for pain/ anxiety
correct any arrhythmias, electrolyte disturbances, acid-base abnormalities
Ix: CXR, Echo, CT depending on cause
consider need for dobutamine (sympathomimetic)
tx underlying cause
what mx B1 receptor stimulant is used for HF and cardiogenic shock?
dobutamine
what is kernig’s sign?
flex both legs at hip to 90
-> pt will be unable to fully straighten one leg down
lumbar spine tenderness
what is Brudzinski’s sign?
neck flexion would cause flexion of legs at hip
discomfort at c spine
mx of meningitis in the community before transfer to hospital?
benzylpenicillin 1.2g IV/IM
tx of meningitis?
<50 yo: ceftriaxone 2g IVI/IM BD
>50 yo: ceftriaxone + ampicillin (to cover listeria)
if viral suspected: add aciclovir
ix of suspected meningitis pt?
Bloods: FBC, U+E, clotting, glucose, ABG
blood cultures
LP: MCS, glucose, virology/ PCR, lactate
contraindications to LP?
raised ICP
cardio/ resp instability
thrombocytopenia
coagulation disorder (DIC)
infection at LP site
focal neuro signs
acute mx of meningitis pt?
A to E approach
O2 15L - SpO2 94-98%
IVI fluid resus
if mainly meningitic: do LP if no CIs, dexamethasone + ceftriaxone
mainly septicaemic: ceftriaxone
+ maintenance fluids
what prophylaxis is available for household contacts of meningitic patients?
Rifampicin
mx of encephalitis?
aciclovir stat
supportive measures in HDU/ITU
phenytoin for seizures
risk factors for cerebral abscess?
infection: ear, sinus, dental
skull #
congenital heart disease
endocarditis
bronchiectasis
immunosuppression
ix of cerebral abscess?
CT/ MRI head- ring enhancing lesion
Bloods: high WCC, high ESR/CRP
tx of cerebral abscess?
neurosurgical referral
abx- e.g. ceftriaxone
treat the raised ICP
definition of status epilepticus?
seizure lasting > 5 min
or
repeated seizures w/o recovery of consciousness in between
ix in status epilepticus?
Blood glucose levels
Bloods: infection markers (WCC, CRP), U+E, Ca/Mg, FBC
ECG, EEG
Consider AED levels, tox screen, LP, CT head, BHCG
1st line mx of status epilepticus?
Lorazepam IV 2-4mg bolus over 30s
2nd dose if no response within 2 min
alternatives:
buccal midazolam 10mg
rectal diazepam 10mg
mx of status epilepticus after 1st line tx (e.g. lorazepam) has failed?
phenytoin 18mg/kg IVI @ 50mg/ min
monitor ECG and BP
CI: bradycardia or heart block
alternative: diazepam infusion
what medication will be considered if cerebral oedema may be the cause of status epilepticus?
dexamethasone
Important things to remember in status epilepticus?
Get anaesthetist early - may need to intubate
treat early with 100ml 20% glucose unless glucose known to be normal
GCS eyes criteria?
4 – Spontaneous eye opening
3 – Open to voice
2 – Open to pain
1 – No opening
GCS verbal criteria?
5 – Orientated conversation
4 – Confused conversation
3 – Inappropriate speech
2 – Incomprehensible sounds
1 – No speech
GCS motor criteria?
6 – Obeys commands
5 – Localises pain
4 – Withdraws to pain
3 – Decorticate posturing to pain (flexor)
2 – Decerebrate posturing to pain (extensor)
1 – No movement
initial primary survey of head injury pt?
A: ? intubation, immobilise C-spine
B: 100%O2, RR
C: IV access, BP, HR
D: GCS, pupils
Treat seizures
E: expose pt and look for other obvious injuries
secondary survey of head injury patient?
Look for:
Lacerations
Obvious facial/skull deformity
CSF leak from nose or ears
Battle’s sign, Racoon eyes
Blood behind TM
C-spine tenderness ± deformity
Head-to-toe examination for other injuries
ix of head injury patient?
CT head + c spine
Bloods: FBC, U+E, glucose, clotting, ABG, EtOH level
mx of head injury patient?
Neurosurgical opinion if signs of ↑ICP, CT evidence of intracranial bleed significant skull #
Admit if:
Abnormalities on imaging
Difficult to assess: EtOH, post-ictal
Not returned to GCS 15 after imaging
CNS signs: vomiting, severe headache
Neuro-obs half-hrly until GCS 15:
GCS, pupils, HR, BP, RR, SpO2, temp
discharge advice for someone who had received a head injury?
Stay with someone for first 48hrs
Give advice card advising return on:
Confusion, drowsiness, unconsciousness
Visual problems
Weakness
Deafness
V. painful headache that won’t go away
Vomiting
Fits
when to intubate after head injury?
GCS ≤ 8
Respiratory irregularity
Spontaneous hyperventilation: PCO2 <4KPa
PaO2 <9KPa on air / <13KPa on O2 or PCO2 >6KPa
cerebral oedema may cause which false localising sign?
6th CN palsy
what is Cushing’s reflex?
raised BP
bradycardia
irregular breathing
Acute Mx of cerebral oedema?
A-> E approach
treat seizures and correct hypotension
elevate bed to 40 degrees
neuroprotective ventilation: PaO2: > 13kPa, PCO2: 4.5 kPa, good sedation
Mannitol or hypertonic saline -> can decrease ICP in the short term but may cause rebound raised ICP later