Emergency Medicine Flashcards
What drugs cause anticholinergic syndrome?
antihistamines, TCA, benztropine
What PLANTS cause anticholinergic syndrome?
Adam and Eve- angels eating an apple
plants: datura (thorn apple) or brugmansia (angel trumpet)
Adam and Eve- angels eating an apple
What are the 6 features of anticholinergic syndrome?
THINK DRY AND TACHY
Red as a beet for cutaneous vasodilation
Dry as a bone for anhidrosis
Hot as a hare for hyperthermia
Blind as a bat for nonreactive mydriasis (dilated pupils)
Mad as a hatter for hallucinations and delirium and finally
Full as a flask for urinary retention
What is the antidote for anticholinergic syndrome?
Antidote: physostigmine
Supportive: benzodiazepine
What meds cause a cholinergic crisis?
acetylcholine, pilocarpine, Organophosphates/ pesticides
What are the 8 signs of cholinergic syndrome?
Think secretions!!
DUMBBELS
Diarrhoea
Urination
Miosis
Bronchorrea, bradycardia (this is what kills you/ killer ‘B’)
Emesis
Lacrimation
Salivation
What is the treatment for cholinergic syndrome?
Remember, cause MIOSIS so treatment is ATROPINE to DILATE pupils. Also does other things.
What are examples of sympathometics?
‘Party drugs’: - Cocaine, (met) Amphetamines, Ecstasy/ MDMA
What are the symptoms of sympathetic syndrome?
HTN, tachycardia
Dilated pupils
Agitations, sweating
Hyperthermia: urgent attention
What is the treatment for sympathometic syndrome?
benzodiazepine and IV hydration
What can cause serotonin syndrome?
Tramadol, SSRI, SNRI, anti-emetic, MAOI
What are the signs/symptoms of serotonin syndrome?
Shivering
Hyperreflexia and myoclonus
Increased temperature
Vital sign instability
Encephalopathy
Restless
Sweating
What is the treatment for serotonin syndrome?
Benzodiaziepine. NOTE IF ACUTE DYSTONIC REACTION, then benztropine
What are the common drugs that can cause hypoventilation?
Narcotics or clonidine
Nacrotic will have tachycardia, clonidine will have brady
What drugs can cause hyPOglycemia (and name antidote)
Insulin and sulfonulurea. Treat with Octreotide. THINK CONGENITAL HYPOINSULINISM
Also beta blockers have the potential for this, use glucagon in poisoning
Treatment for anaphylaxis. DOSE and strength of Adrenaline
0.01 mL/kg of 1:1000 (maximum 0.5 mL)
or 10micrograms/kg
Average lifespan of platelets?
10 days
Predisposition to bone marrow failure associated with dyskeratosis congenita results primarily from a defect in what critical cellular process
Telomere maintenance
What contirbutes the most to serum osmolality
Sodium
What formula can be used to estimate the correct size of an uncuffed endotracheal tube for use in children?
(Age/4) +4
Earliest gestation where pupils respond to light?
32 weeks
Hymen shape in newborn vs pre-puberty
Annular – most common in newborns/infants.
Crescentic - during the preschool and early primary school years the hymen is commonly observed to have a crescentic shape.
Follows alphabetical order. Fimbriated is redundant, and common in puberty/neonatal due to oestrogen
Is it hard to obtain reflexes in viral myositis?
Yes, due to pain with dorsiflexion and tight muscles.
What does GHB do?
Gamma Hydroxybutyrate
the patient may have a period of euphoria that is rapidly followed by a period of profoundly depressed level of consciousness (hence its reputation as a date rape drug).