Emergency Drugs

Question 1

Adenosine (Route & Indications)

Answer 1

Route: IV, repeated over 2 min intervals

Indications: Paroxysmal or unstable supraventricular tachycardia (SVT)

Question 2

Adenosine (MOA, Duration of action)

Answer 2

MOA: Blocks / slows down
conduction through AV
node

Duration of action: within minutes

Question 3

Adenosine (Adverse effects, Drug-Drug interactions)

Answer 3

AE: Nausea, flushing, headache, bradycardia

Drug-drug interaction:
- Increased effect with dipyridamole
- Reduced effect with xanthines

Question 4

Adrenaline (Route & Indications)

Answer 4

Route: IV, SC

Indications:
- Treatment of allergic reactions & anaphylaxis
- Treatment of septic shock related hypotension
- Treatment of cardiac arrest

Question 5

Adrenaline (MOA, Duration of action)

Answer 5

MOA:
- Acts on alpha and beta adrenergic receptors
- Alpha-adrenergic action reduces vasodilation and vascular permeability, preventing fluid loss and hypotension during anaphylaxis
- Relaxes smooth muscles in the bronchi and iris, and serves as a histamine antagonist, making it effective in treating allergic reactions

Duration of action:
- SC may produce bronco-dilation within 5-10 mins
- Maximal effects may occur within 20mins

Question 6

Adrenaline (Adverse effects, Drug-Drug interactions)

Answer 6

AE: