Embryology Flashcards
germ layers that form ocular structures
ectoderm and mesoderm
neural plate
made from ectoderm, turns into CNS and ocular structures
optic pit pathology
no closure of the optic fissure, usually inferior temporal region - but smaller than coloboma
coloboma
optic fissure doesn’t close correctly - inferior nasal defect in optic disc, retina, ciliary body, or iris
surface ectoderm leads to…
lens, corneal epithelium, epithelium of eyelids and cilia, Meibomian glands, glands of zeis and moll, epithelium lining nasolacrimal system
neural ectoderm leads to…
retinal pigment epithelium, neural retina, optic nerve fibers, neuroglia, epithelium of ciliary body, epithelium of iris, iris sphincter and dilator
neural crest leads to…
corneal stroma, corneal endothelium, (most of) sclera, trabecular structures, uveal pigment cells, uveal connective tissue, ciliary muscle, meninges of optic nerve, and vascular pericytes
neural crest leads to…
corneal stroma, corneal endothelium, (most of) sclera, trabecular structures, uveal pigment cells, uveal connective tissue, ciliary muscle, meninges of optic nerve, and vascular pericytes
EOM embryology
mesenchymal (mesoderm) origin
order of EOM development
1st - muscles innervated by CNIII, 2nd - lateral rectus, 3rd. superior oblique
tendon sheath of EOM development
18 months post natal
point where globe reaches adult size
3 y.o.
point where orbit reaches adult size
16 y.o.
first evident orbital bone
maxilla @ week 6
orbital bone development/fusion
6 and 7 gestational months