EMBRYOLOGY Flashcards
Where does foregut start and end
starts from the mouth to the common bile duct
Where does midgut start and end
starts from the common bile duct to 2/3rds of the transverse colon
where does handgun start and end
starts from 2/3rds of the transverse colonto the anal canal
what is embryonic folding
During the 4th week of development the embryo begins to fold and change shape from a flat trilaminar disc into a cylinder - this process is known as embryonic folding
how does embryonic folding occur
Folding occurs in two planes, the horizontal & medial planes
Why does embryonic folding occur in two planes
Folding occurs in two planes due to the differing rates of growth of the embryonicstructures
Folding in the horizontal planeresults in the formation of
of the two lateral body folds
Folding in the medial plane results in the
the formation of the cranial & caudal folds
What is mainly responsible for the formation of the GI tract
the endoderm
As embryonic folding continues, the endoderm moves towards the midline and fuses
incorporating the dorsal part of the yolk sac to form the primitive gut tube
The primitive gut is derived from the
endodermand the visceral mesoderm:
Endoderm gives rise to
Epithelial lining of digestive tract
Hepatocytes of the liver
Endocrine and exocrine cells of the pancreas
Visceral mesoderm gives rise to
- Muscle, connective tissue & peritoneal components of the wall of the gut
- Connective tissue for the glands
The primitive gut tube, differentiates into three distinct parts
the foregut, midgut & hindgut
As embryonic folding continues, the connection to the yolk sac narrows into a stalk called the
vitelline duct
How many pharyngeal arches are there
There are five arches; 1,2,3,4 & 6 (there is no 5th in humans - sort of combines into the 4th)
What are the pharyngeal arches are part of
foregut
when do the pharyngeal arches develop
In the 4th & 5th week of fetal life
Where do the pharyngeal arches extend from to
Extends from the oropharyngeal membrane to the respiratory diverticulum
what are the pharyngeal arches made of
Formed of masses of mesenchymal tissue (connective tissue derived from mesoderm) which are invaded by cranial neural crest cells
Each pharyngeal arch is covered externally by
endoderm (forming the pharyngeal clefts)
ach pharyngeal arch is covered internally by
ectoderm (forming the pharyngeal pouches)
Each arch has its own
nerve supply, arterial supply & venous supply
innervation of first arch
Mandibular nerve (V3 - i.e third branch of trigeminal (V)