Embryology Flashcards
What is a risk factor for heart malformation?
Diabetic mother
What is the gene linked to many heart malformations?
NKX2
What are some environmental factors for heart malformation?
Rubella virus
German measles
Diabetes
Retinoic Acid disturbance
During development, what will divert blood away from the lungs?
Ductus arteriosus
Arrange those is the correct chronologic order:
Head-Tail and Lateral Folding
Gastrulation
Heart Folding and Septation
Gastrulation
Head-Tail and Lateral Folding
Heart Folding and Septation
What will the ductus arteriosus become?
Ligamentum arteriosus. It will close to let blood go to the lungs
What is the first hemopoietic organ?
Yolk sac hemopoiesis
What is the commun precursor of hemopoietic stem cells and angioblasts?
Hemangioblasts
What are the two embryological roles of the visceral pericardium?
Forms the epicardium and forms the dorsal mesocardium
What is dextrocardia?
The apex of the heart points towards the right (heart is inverted)
Is dextrocardia lethal?
Only in isolated dextrocardia (where only the heart is inverted and not the other organs)
Atrio-ventricularis communis is what?
An absence of endocardial cushions fusion during embryology
Atrial septal defects (ASD) and Ventricular septal defects (VSD) are signs of what?
Incomplete endocardial cushions fusion during embryology
What is the name of the anomaly occuring when the aortico-pulmonary septum does not form?
Persistent Truncus Arteriosus
What is the Tetralogy of Fallot?
When the truncus arteriosus is unequally divided so that one outlet is larger than the other
