Embryology Flashcards

1
Q

How long is the germinal period?

A

0-2 weeks

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2
Q

Embryonic period lasts?

A

2-8 weeks

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3
Q

Fetal period lasts?

A

8-40 weeks

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4
Q

define gastrulation

A

Early embryo reorganizes into 3 tissue layers. All cells have the same DNA; however, different cells now begin to “turn on”
(express) different genes to become different
organs.

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5
Q

what are the 3 layers of gastrulation

A

endoderm, mesoderm, ectoderm

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6
Q

endoderm

A

digestive, respiratory systems

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7
Q

mesoderm

A

muscles, skeleton, circulatory system, reproductive system, dermis

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8
Q

ectoderm

A

CNS, PNS, eyes, ears, outer skin

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9
Q

neurulation

A

process where the neural plate forms the neural tube

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10
Q

closure of cranial neuropore happens when?

and what happens if it doesnt close?

A

day 25; no formation of brain, not a viable fetus

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11
Q

closure of caudal neurpore happens when?

what can occur if it doesnt close?

A

day 28; spina bifida

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12
Q

brain development begins when?

A

day 28

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13
Q

3 main divisions of the brain

A

prosencephalon (forebrain)
mesenencephalon (midbrain)
rhomboencephalon (hindbrain)

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14
Q

Cells formed in segmental pairs along the neural tube from mesoderm layer.
Give rise to vertebrae, muscles of back and body wall, and dermis ofskin.

A

somites

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15
Q

Cells in
dorsolateral regions form
muscle cells; migrate
beneath dorsal epithelium (dermatome).

A

myotome

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16
Q

cells in
ventromedial wall lose
epithelial arrangement; become mesenchymal.

A

sclerotome

17
Q

embryo week 4

A
Neural folds fuse: folding of embryo into human-like shape
 Arm and leg buds appear
 Heart pumps blood
 Pharyngeal arches visible
 Length 4-5 mm
 4-12 pairs of somites
18
Q

embryo week 5

A

Lens placodes appear
 Primitive mouth
 Digital rays on hands
 Forebrain, midbrain and hindbrain form

19
Q

embryo week 6

A
Primitive nose
 Primary palate
 Auricular Hillocks form – precursor to visible auricle of ear Reflex Response to Touch
 Digital Rays begin to Develop
 Length 9-14 mm
20
Q

embryo week 7

A

Eyelids begin to form
 Motor behavior first appears as slow neck extensions
 Limbs undergo considerable change in week 7
 Notches appear between digitalrays

21
Q

embryo week 8

A

Length 3.5 cm; Weight 2 g (.004 lb)
 Ovaries and testes distinguishable
 Eyes, ears, nose, mouth, digits formed
 Muscle contraction appear - lateral flexion movements
 Can see startle, hiccup, isolated arm/leg movement

22
Q

week 9

A
increased activity and rapid growth
 Length, 5 cm
 Sensory organs developing
 Bone ossification Begins
 Head retroflexion
 Head rotation
23
Q

week 12

A
Sex is Externally Recognizable
Head large for body
Brain configuration nearly 
complete
Blood Forming in Marrow
Sucking/Swallowing
Yawn
24
Q

weeks 13-16

A

Breathing and swallowing motion appears
 Tactile stimulation elicits movements
 Growth very rapid
 Limb movements increasingly coordinated

25
Q

week 16

A
Motor activity begins
 Scalp hair present
 Trunk size increasing relative to head size
 Heart muscle developed
 Sense organs formed
26
Q

week 17

A

grasp reflex appears

27
Q

week 20

A

Lower extremities have grown appreciably
 Myelination of spinal cord begins
 Fetus turns and moves easily

28
Q

week 24

A

Lungs become viable organs

29
Q

week 25

A

third trimester begins

30
Q

week 26

A

eye opening

31
Q

week 28

A

Increasing fat tissue development
 Retina layered and light-receptive
 fetus turns head down

32
Q

week 32

A

Weight increasing more than length

Taste sense operative

33
Q

week 36

A

Body More Rounded

 Ossification begins distal femur

34
Q

week 40

A

myelination of brain begins

35
Q

intramembranous ossification

A

replacement of connective tissue membranes with bony tissue

36
Q

endochondral ossification

A

replacement of hyaline cartilage with bony tissue

37
Q

limb buds appear at?

upper limbs begin development?

A

week 4; 1-2 days before lower limbs

38
Q

most muscle develops from?

39
Q

teratogens

A

cause human birth defects:

  • congenital infection
  • alcohol
  • smoking
  • drugs
  • poor nutrition