Embryology Flashcards
Subventricular Zone gives rise to:
Neurons of the Olfactory Bulb
Dentate Gryus gives rise to the:
Hippocampus
External Granule Layer gives rise to:
Cerebellar Granule Cells
Sonic Hedgehog (Shh)
-alters dorsal-ventral patterning
Telencephalon
-becomes cerebral hemispheres
Diencephalon
-becomes thalamic structures, 3rd ventricle
Mesencephalon
-becomes midbrain, cerebral aquaduct
Metancephalon
-becomes pons and medulla
Myelencephalon
-becomes medulla
Rhombencephalon
-lumen becomes 4th ventricle
Homeobox (Hox)
- regulate genes that code for vertebral column
- rostral-caudal patterning
Alar Plate
-forms dorsal portion of spinal cord
Basal Plate
-forms ventral portion of spinal cord
Sulcus Limitans
-separates alar and basal plates
Chranioraschisis
- most severe neural tube defect
- failure of closure of spinal cord and skull