Drugs Flashcards

1
Q

Bethanechol

A

Muscarinic Cholinergic Receptor Agonist

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2
Q

Pilocarpine

A

Muscarinic Cholinergic Receptor Agonist

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3
Q

Nicotine

A

Nicotinic Cholinergic Receptor Agonist

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4
Q

Muscarinic Cholinergic Receptor Agonists

A
  • acetylcholine
  • bethanechol
  • pilocarpine
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5
Q

Nicotinic Cholinergic Receptor Agonists

A
  • acetylcholine

- nicotine

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6
Q

Atropine

A

Muscarinic Cholinergic Receptor Antagonist

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7
Q

Cholinergic Muscarinic Receptor Antagonists

A

Atropine

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8
Q

Physostigmine

A

Acetylcholinesterase Inhibitor (same effect as Cholinergic Agonist)

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9
Q

Neostigmine

A

Acetylcholinesterase Inhibitor (same effect as Cholinergic Agonist)

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10
Q

Edrophonium

A

Acetylcholinesterase Inhibitor (same effect as Cholinergic Agonist)

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11
Q

Organophosphates

A

Acetylcholinesterase Inhibitor (same effect as Cholinergic Agonist)

  • irreversible AChE inhibitors
  • can cross BBB
  • atropine is antidote and pralidoxipine repleats AChE
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12
Q

Acetylcholinesterase Inhibitors

A
  • physostigmine
  • neostigmine
  • edrophonium
  • organophosphates
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13
Q

Pralidoxime

A
  • aka 2-PAM
  • cholinesterase reactivator
  • antidote to organophosphate poisoning
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14
Q

Epinephrine

A

Adrenergic Agonist

a1, a2, b1, b2 (nonselective)

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15
Q

Norepinephrine

A

Adrenergic Agonist

a1, a2, b1

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16
Q

Dopamine

A

Adrenergic Agonist

d1, d2 direct agonist plus indirect agonists

17
Q

Adrenergic Agonists

A

Epinephrine (a1, a2, b1, b2)
Norepinephrine (a1, a2, b1)
Dopamine (d1, d2)

18
Q

Botulinum Toxin

A

-inhibits acetylcholine release (synaptobrevin-syntaxin-SNAP25)

19
Q

Black Widow Spider Venom

A

-increases acetylcholine release

20
Q

Atracurium

A

Nicotinic Receptor Antagonist

-NMJ competitive blocker (non-depolarizing)

21
Q

Rocuronium

A

Nicotinic Receptor Antagonist

-NMJ competitive blocker (non-depolarizing)

22
Q

Succinylcholine

A

Nicotinic Receptor Antagonist

-NMJ depolarizing blocker

23
Q

Acetylcholine

A

Muscarinic and Nicotinic Adrenergic Receptor Agonist