embryology Flashcards

1
Q

define embryology

A

the study of embryos and their development

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2
Q

pre embryonic stage

A

first 2 weeks

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3
Q

when is the developing human referred to as en embryo

A

weeks 3-8

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4
Q

the pre embryonic and embryonic stage are characterized by

A

cell division, migration , and differentiation

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5
Q

when is a human referred to as a fetus

A

from the 9th week of gestation until birth

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6
Q

when are all organ systems structure ?

A

by week 9

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7
Q

define gastrulation

A

cellular rearrangement which involved migration, invagination, and differentiation of the epiblast

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8
Q

during gastrulation the 2 cell layers become

A

3 germ cell layers and the bodily axes in the mature adult are created

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9
Q

mesoderm

A

notochord
musculoskeletal system
muscular layer of stomach
circulatory system

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10
Q

ectoderm

A

epidermis of skin
cornea and lens of eye
nervous system

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11
Q

when do dermatomyotomes originate

A

3rd week of embryogenesis

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12
Q

after day 20 the mesoderm differentiates into

A

44 pairs of semite’s and then change into 31 sets of spinal nerves

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13
Q

dorsal portion of somites

A

comes from dermis , as limbs grow the dermis i stretched and moved down the limb

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14
Q

ventral portion of somites

A

consists of sclerotome, the precursor to the ribs and vertabrae

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15
Q

during the 4th week of development , the upper limbs buds appear as elevations of

A

C5-T1 segments if the anterolateral body wall

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16
Q

the lower limb buds grow

A

laterally from the broader bases formed by the L2-S2 segments

17
Q

flex urges occur where

A

gaps develop between the precursors of the long bones

18
Q

by the end of the 7th week the proximal parts of the upper and lower limbs

A

undergo a 90 degree torsion around their long axes but in opposite directions
elbows go caudally and knee cranially

19
Q

what is the precursor structures of the limbs

A

limb buds

20
Q

syndactyly

A

represents fusion of two or more digits

21
Q

polydactyly

A

extra digits , typically occurs bilaterally

22
Q

macrodactyly

A

enlarged digits

23
Q

adactyly

A

absence of digits

24
Q

ectrodactyly

A

“lobster-claw deformity” typically missing middle digit and occurs unilaterally

25
Q

amelia

A

complete a sense of one or more extremities

26
Q

meromelia

A

partial absence of one or more extremities

27
Q

phocomelia

A

shortened lower extremities

28
Q

following gastrulation , rudiments of the CNS develop from the ectoderm in the process of

A

neurulation

29
Q

what vitamin is important to the healthy development of the neural tube and preventing neural tube defects?

A

folate one of the vitamin b

30
Q

the neural plate border separates thh

A

ectoderm from the neural plate

31
Q

What is a disorder which two sides of the vertebral arches fail to fuse during development, resulting in an open vertebral canal

A

spina bifida

32
Q

Spina bifida occulta

A

occurs when there is a defect in the vertebral arch of L5 or S1
10% of ppl
pt is asymptomatic with a tuft of hair

33
Q

meningocele

A

large outpouching of the meninges that contains cerebrospinal fluid

34
Q

myelomeningocele

A

large outpuching of the meninges that is a portion of the spinal cord

35
Q

anencephaly

A

absence of a major portion of the brain, skull, and scalp
fetal neural tube defect
folic acid
failure of neural tube to close at the base of the skull