Embryology Flashcards

1
Q

What is embryology

A

Phase between fertilisation and birth

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2
Q

Embryogenesis - from water to land
Problems + solutions

A

Problems
Dehydration, food availability
Solution
Formation of extra embryonic layers
- amniotic egg

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3
Q

Extra embryonic layers

A

Amnion
Yolk
Allantois
Chorion

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4
Q

Amnion

A

Prevents dehydration and protects embryo

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5
Q

Yolk

A

Nutrition

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6
Q

Allantois

A

Sequestering waste products

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7
Q

Chorion

A

Exchanging respiratory gasses

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8
Q

Characteristics of choradata

A

Notochord
Dorsal hollow nerve cord
Muscular anal tail
Pharyngeal slits or clefts

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9
Q

What distinguishes vertebrates from other chordates

A

Development of back bone - vertebral column
Cranium
Endoskeleton

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10
Q

What is the phylotipic stage

A

Tailbud stage

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11
Q
  1. Fertilisation
A

Fusion of the nucleus of a male gamete with the nucleus of a female gamete results in production of a zygote

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12
Q

Sperm

A

Highly conserved features
Head has a cap called the acrosome which contains hydrolytic enzyme which help the sperm penetrates the egg

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13
Q

Hydrolytic enzymes

A

Hyaluronidase - penetrates corona radiata
Acrosin - digests the sons pellucida

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14
Q

Reproductive strategies

A

R selected - large no. Of small young, no parental care, rapid growth, short lived, high mortality risk

K selected - small no. Large young, parental care, long maturity, long lived

Effected by temp

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15
Q

Telolecithal egg

A

Yolk down one end of the egg
- birds, reptiles, fish

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16
Q

Isolecithal egg

A

Yolk is dispersed
- mammals -

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17
Q

Amount of yolk

A

Small
Microlecithal - mammals
Mesolecithal - amphibians
Macrolecithal - fish, reptiles, birds
Large

18
Q

Egg laying

A

Oviparous

19
Q

Viviparous

A

Give birth to live young

20
Q
  1. Cleavage
A

The series of mitotic divisions that take the zygote to a mass of smaller cells, blastula/blastocyst/blastoderm

21
Q

Two different forms of cleavage

A

Holoblastic - complete split of cells
- isolecithal
- microlecithal, mesolecithal

Meroblastic - partial cleavage
- telolecithal
- macrolecithal

22
Q

Cleavage in amphibians

A

Mesolecithal egg, radial holoblastic cleavage

23
Q

Cleavage in birds, fish and reptiles

A

Macrolecithal, discoidal meroblastic cleavage

Division occurs on top of yolk

Blastoderm
Bilaminar disc - 2 layers of cell formed;
1. Epiblast
2. Hypoblast

24
Q

Cleavage in mammals

A

Microlecithal egg, rotational holoblastic cleavage

Also asynchronous - not all blastomeres divide at the same time

Trophoblast - outer layer of cells = develops into placenta

25
Q
  1. Gastrulation
A

Rearrangement of the cells by migration and division resulting in the formation of three embryonic germ layers :
1. Endoderm 2. Mesoderm 3. Ectoderm

26
Q
  1. Neurulation
A

Folding process to form the neural tube which become the spinal chord and central nervous system

27
Q

Formation of yolk and allantois

A

Endoderm and mesoderm

28
Q

Formation of chorion and amnion

A

Ectoderm and mesoderm

29
Q

Placenta formation in mice

A

Formed for the Allantois and chorion

30
Q
  1. Organogenesis
A

The series of organised integrated process that transforms an amorphous mass of cells into a complete organ in the developing embryo

31
Q

What does the ectoderm go on to form

A
  • nervous system
  • skin
  • epithelia of eye, ear and nose
32
Q

Paradise mesoderm forms?

A

Connective tissue
- vertebrae, ribs
- muscle + limbs
- dermis (skin)

33
Q

Intermediate mesoderm forms?

A

Urogenital system
- kidneys, gonads

34
Q

Lateral plate mesoderm forms?

A

Circulatory system
- heart, vessels

35
Q

Archenteron

A

The primary gut formed during gastrulation

36
Q

Endoderm forms?

A

Intestines, lungs, liver, pancreas, thymus

37
Q
  1. Differentiation
A

Embryonic cells specialise into diverse tissue structures

38
Q

Totipotent cells

A

each single blastomere contains the information to develop a complete individual

39
Q

What gene regulates organogenesis

A

Homeobox gene (hox gene)

40
Q

Homobox gene

A

Involved in differential gene expression and morphogenesis
Highly homologous
Master controllers

41
Q

Homeotic genes

A

Determine animal structure and they contain DNA sequences called homeoboxes