Embryology Flashcards
From which embryological structure does the definitive kidney develop?
Metanephros
What does the ureter develop from?
Ureteric Bud
Intermediate Plate Mesoderm develops what
Urogenital System (Kidneys and Repro)
Lateral Plate Mesoderm develops
Body Cavity
Paraxial Mesoderm develops
Somites
What is Allantois
Outpouching of endoderm at hindgut that extends into body stalk
What is Cloaca
single posterior opening
The Cloaca gets divided into
Rectum Posteriorly and Urogenital Sinus Anteriorly
Urogenital septum divides the cloaca into rectum
posteriorly and urogenital sinus anteriorly
Allantois gets obliterated at birth to form
Urachus
Urogenital sinus forms
Urinary Bladder
How many sets of kidneys develop sequentially during nephrogenesis
3 Sets
How many sets of kidneys develop sequentially during nephrogenesis
3 Sets
When does intermediate mesoderm become pronephros
Early in fourth week
What makes up the Pronephros
Pronephric duct + rudimentary pronephric tubules
Pronephric duct drains into
Cloaca
When does the Pronephros mainly degenerate by
5th Week
In week 4 what does the pronephric duct become
Mesonephric Duct
Mesonephric tubules drain into
Mesonephric Duct
Mesonephros functions as kidney for how many weeks
4
What is the Metanephros also known as
Definitive Kidney
When does the metanephros start to develop from
Week 5
When does the metanephros start to function from
Week 9
The metanephros consists of
Ureteric Bud that comes off Mesonephric Duct
Metanephric Mesoderm
What is the most caudal part of intermediate mesoderm
Metanephric mesoderm
Much of the mesonephros will be incorporated into the
developing gonad
The mesonephric tubules become the
Rete Testis
The mesonephric duct becomes the
Vas Deferens
In females the mesnephros become the
ovary but tubules and mesonephric duct degenerate
The ureteric bud undergoes repeated branching where
Distal end
The stalk of the ureteric bud becomes the
Ureter
The expanded cranial end of ureteric bud becomes
renal pelvis
The first 4 generations of branches of ureteric bud become confluent to become
major calyces
The next 4 generations of ureteric bud form
minor calyces
The remaining generations after the first 8 generations of ureteric bud become
Collecting Tubules
The ureteric bud and metanephric mesoderm do what to each other
reciprocally induce each other
The ureteric bud and metanephric mesoderm do what to each other
reciprocally induce each other
The nephron is made up of
Renal Corpuscle and PCT + Loop of Henle + DCT
The uriniferous tubule is made up of
Nephron and Collect Duct
Nephron develops from
Metanephric Mesoderm
Collecting Duct and Calyces, Pelvis and Ureter develop from
Ureteric Bud
Hilum of kidney rotates from
Ventral to Medial (90 Degrees)
Ascent of kidneys stop when they come in contact with
Adrenal Glands
Intermediate Mesoderm develops into
Rudimentary Pronephros in Neck Week 4
Ureteric Bud grows out of caudal end of
Mesonephric Duct and branches to form Renal Pelvis, Calyces and Collect Duct
The ureteric bud and metanephric mesoderm do what to each other
Reciprocally induce each other
Final position of hilum
Medial
