Embryology Flashcards

1
Q

Early development of msk development begins

A

Near end of 4th Week

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2
Q

Activation of mesenchymal cells in ask development happens where

A

Somatic Lateral Mesoderm

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3
Q

What happens in Day 24 of MSK Development

A

Upper Limb Bud Appears

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4
Q

What happens if you remove Hoxa 11 and Hoxd 11 genes in MSK Development

A

Radius and ulna do not develop

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5
Q

Limb buds elongate by

A

proliferation of mesenchyme

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6
Q

Upper limb buds develop opposite

A

Caudal Cervical Segments

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7
Q

Lower lim buds form opposite

A

Lumbar and Sacral Segments

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8
Q

At apex of each limb bud the ectoderm thickens to form

A

apical ectodermal ridge

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9
Q

By the end of what week mesenchymal tissue in hand plates have condensed to form digital rays

A

6th week

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10
Q

During what week digital rays are formed in foot plates

A

7th Week

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11
Q

Primary centres of ossification in MSK appear in weeks

A

8-12 Weeks

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12
Q

Which bone does not go through endochondrial ossification

A

Clavicle

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13
Q

Upper limbs rotate by how many degrees laterally in msk development

A

90 Degrees

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14
Q

Extensors in MSK embryology are on which surfaces in the. end

A

Lateral and Posterior

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15
Q

Lower Limbs rotate by how many degrees medially so extensors are on anterior surface

A

90 Degrees

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16
Q

Thumb is on which surface in msk development

17
Q

Big toe is on what surface in embryology development

18
Q

During the 5th Week, Peripheral nerves grow from what into mesenchyme of limbs

A

Developing Limb Plexus

19
Q

What is Amelia in Birth Defects of Limbs

A

Total Absence

20
Q

What is Meromelia in birth defects of limbs

A

Partial Absence

21
Q

What is Phocomelia in birth defects of limbs

A

Some long bone absence

22
Q

Lobster claw foot can be inherited as

A

Autosomal Dominant Trait

23
Q

Critical period of limb development

A

24-36 days after fertilisation

24
Q

What is polydactyly

A

Presence of more than 6 digits on hand or feet

25
What is syndactyly
Common birth defect of hand or foot
26
What is cutaneous syndactyly
Webbing between digits and more frequent in foot than hand
27
What is osseous syndactyly?
Fusion of bones
28
What can Thalidomide do?
Cause absence or deformity of long bones in sensitive period 4-8 weeks
29
What is congenital clubfoot also known as
Tapes Equniovarus
30
What happens to foot position in congenital clubfoot
Sole of foot is turned medially and foot inverted
31
How does developmental dysplasia of hip happen
Abnormal development of acetabulum
32
How does developmental dysplasia of hip happen
Abnormal development of acetabulum
33
Generalised Joint Laxity is associated with
Congenital Dislocation of Hip