Embryology Flashcards

1
Q

Early development of msk development begins

A

Near end of 4th Week

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2
Q

Activation of mesenchymal cells in ask development happens where

A

Somatic Lateral Mesoderm

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3
Q

What happens in Day 24 of MSK Development

A

Upper Limb Bud Appears

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4
Q

What happens if you remove Hoxa 11 and Hoxd 11 genes in MSK Development

A

Radius and ulna do not develop

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5
Q

Limb buds elongate by

A

proliferation of mesenchyme

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6
Q

Upper limb buds develop opposite

A

Caudal Cervical Segments

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7
Q

Lower lim buds form opposite

A

Lumbar and Sacral Segments

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8
Q

At apex of each limb bud the ectoderm thickens to form

A

apical ectodermal ridge

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9
Q

By the end of what week mesenchymal tissue in hand plates have condensed to form digital rays

A

6th week

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10
Q

During what week digital rays are formed in foot plates

A

7th Week

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11
Q

Primary centres of ossification in MSK appear in weeks

A

8-12 Weeks

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12
Q

Which bone does not go through endochondrial ossification

A

Clavicle

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13
Q

Upper limbs rotate by how many degrees laterally in msk development

A

90 Degrees

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14
Q

Extensors in MSK embryology are on which surfaces in the. end

A

Lateral and Posterior

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15
Q

Lower Limbs rotate by how many degrees medially so extensors are on anterior surface

A

90 Degrees

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16
Q

Thumb is on which surface in msk development

A

Lateral

17
Q

Big toe is on what surface in embryology development

A

Medial

18
Q

During the 5th Week, Peripheral nerves grow from what into mesenchyme of limbs

A

Developing Limb Plexus

19
Q

What is Amelia in Birth Defects of Limbs

A

Total Absence

20
Q

What is Meromelia in birth defects of limbs

A

Partial Absence

21
Q

What is Phocomelia in birth defects of limbs

A

Some long bone absence

22
Q

Lobster claw foot can be inherited as

A

Autosomal Dominant Trait

23
Q

Critical period of limb development

A

24-36 days after fertilisation

24
Q

What is polydactyly

A

Presence of more than 6 digits on hand or feet

25
Q

What is syndactyly

A

Common birth defect of hand or foot

26
Q

What is cutaneous syndactyly

A

Webbing between digits and more frequent in foot than hand

27
Q

What is osseous syndactyly?

A

Fusion of bones

28
Q

What can Thalidomide do?

A

Cause absence or deformity of long bones in sensitive period 4-8 weeks

29
Q

What is congenital clubfoot also known as

A

Tapes Equniovarus

30
Q

What happens to foot position in congenital clubfoot

A

Sole of foot is turned medially and foot inverted

31
Q

How does developmental dysplasia of hip happen

A

Abnormal development of acetabulum

32
Q

How does developmental dysplasia of hip happen

A

Abnormal development of acetabulum

33
Q

Generalised Joint Laxity is associated with

A

Congenital Dislocation of Hip