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Extras > Embryo Extras > Flashcards

Embryo Extras Flashcards

1
Q

polydactyly

A

hands with extra fingers: wk 6, upregulation of ZPA

feet with “mirrored, duplicated toes”: wk 7, duplication of ZPA

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2
Q

syndactyly

A

downregulation of BMP at wk 8 (fused digits)

same for hands and feet

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3
Q

Thalidomide

A

Meromila: missing limbs
Amelia: No limbs
Phocomilia: shortened limbs with hands/feet nearer body

Partial disruption of hox genes
Mainly issue with FGF and AER

wk 4-8 affected

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4
Q

prune belly syndrome

A

abnormal migration of hypaxial mesoderm and intermediate mesoderm (gonads)

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5
Q

poland syndrome

A

abnormal migration of hypaxial muscle

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Extras (23 decks)

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