Embryo Flashcards
1st aortic arch
Maxillary artery
1st is max
2nd aortic arch
Stapedial artery and hyoid artery
Second = stapedial
3rd aortic arch
Common carotid artery and proximal part of internal carotid artery
C is 3rd letter
4th aortic arch
On left, aortic arch; on right, proximal part of subclavian artery
4th arch = 4 limbs
6th aortic arch
Proximal part of pulmonary arteries and (on left only) ductus arteriosus
1st branchial arch
Cartilage: Meckel cartilage, Mandible, Malleus, incus, sphenoMandibular ligament
Muscles: Muscles of mastication (temporalis, Masseter, lateral and Medial pterygoids), Mylohyoid, anterior belly of digastric, tensor tympani, tensor veli palatini)
Nerves: CN V2 and V3 chew
Abnormalities/Comments: Treacher Collins syndrome - 1st arch neural crest fails to migrate causes mandibular hypoplasia, facial abnormalites
2nd branchial arch
Cartilage: Reichert cartilage: Stapes, Styloid process, lesser horn of hyoid, Stylohyoid ligament
Muscles: Muscles of facial expression, stapedius, Stylohyoid, platySma, posterior belly of digastric
Nerves: CN VII (facial expression). Smile
Abnormalities/Comments: Congenital pharyngocutaneous fistula - persistence of cleft and pouch -> fistula between tonsillar area and lateral neck
3rd branchial arch
Cartilage: greater horn of hyoid
Muscles: Stylopharyngeus (think of styloPHARYNGEUS innervated by glossoPHARYNGEAL nerve)
Nerves: CN IX (stylopharyngeus) swallow stylishly
Abnormalities/Comments:
4th-6th branchial arch
Cartilage: Thyroid, cricoid, arytenoids, corniculate, cuneiform
Muscles: 4th - most pharyngeal constrictors, cricothyroid, levator veli palatini. 6th - all intrinsic muscles of larynx except cricothyroid
Nerves: 4th - CN X (superior laryngeal branch) simply swallow. 6th - CN X (recurrent laryngeal branch) speak.
Abnormalities/Comments: Arches 3 and 4 form posterior 1/3 of tongue; arch 5 makes no major contributions.
Mnemonic for arches
When at the golden ARCHES, children tend to first chew (1), then smile (2), then swallow stylishy (3), or simply swallow (4), and then speak (6)
Arches are mesoderm
1st branchial pouch
Derivatives: Develops into middle ear cavity, eustachian tube, mastoid air cells
Notes: 1st pouch contributes to endoderm-lined structures of ear
2nd branchial pouch
Derivatives: Develops into epithelial lining of palatine tonsils
Notes:
3rd branchial pouch
Derivatives: Dorsal wings - develop into inferior parathyroids. Ventral wings - develop into thymus
Notes: 3rd pouch contributes 3 structures (thymus, left and right inferior parathyroids). 3rd pouch structures end up below 4th pouch structures
4th branchial pouch
Derivatives: Dorsal wings - develop into superior parathyroid
Notes:
Mnemonic for branchial pouches
Ear, tonsils, bottom to top: 1 (ear), 2 (tonsils), 3 dorsal (Bottom = inferior parathyroids), 3 ventral (To = thymus), 4 (Top = superior parathyroids).
Pouches are endoderm
DiGeorge Syndrome
3rd and 4th branchial pouch issue. No thymus or parathyroid (hypocalcemia). Also associated with cardiac defects (conotruncal anomalies).
1st branchial cleft
External auditory meatus
Branchial clefts are from ectoderm
2nd-4th branchial cleft
form temporary cervical sinuses, which are pbliterated by proliferation of 2nd arch mesenchyme.
Branchial clefts are from ectoderm
Anterior 2/3 of tongue formation
1st and 2nd branchial (pharyngeal) arch. Thus sensation via CN V3, taste via CN VII
Posterior 1/3 of tongue formation
3rd and 4th branchial (pharyngeal) arch. Thus sensation and taste mainly by CN IX, extreme posterior by CN X.
Lesion of CN IX - loss of gag reflex, loss of sensation over upper pharynx, p. tongue, tonsils, middle ear cavity, loss taste sensation over posterior 1/3 tongue.
Motor of tongue
CN XII to hypoglossus (retracts and depresses tongue), genioglossus (protrudes tongue), styloglossus (draws sides of tongue up to swallow).
CN X to palatoglossus - elevates posterior tongue during swallowing.
Taste innervation for tongue
CN VII, IX, X (solitary nucleus)
Pain innervation for tongue
CN V3, IX, X
Motor innervation for tongue
CN X, XII