Emam 2-AB Flashcards
What is a sensory receptor?
ransduce physical signals (detect stimuli) into encoded neural signals, which transport information to nerve centers
what kind of neurons are afferent
sensory
What kind of neurons are efferent
motor neurons
What are interneurons
neurons that are exclusively in the CNS
what are gated channels activated by
a stimulus, such as a change of voltage across the membrane
What is a sodium potassium pump
transports Na+ and K + across the cell membrane. Sodium os actively removed from the cell via this
define synapse
decision and integration points in the nervous system
What do synaptic vesicles contain
neurotransmitters
What do action potentials open
voltage sensitive Ca2+ channels, that cause the vesicle to move the membrane of the terminal bouton
Define NT
endogenous chemicals that allow neurons to communicate with each other throughout the body
What is the synaptic cleft?
when synaptic vesicle fuses with the cell membrane, the NT it contains is released into the synaptic cleft where it binds to receptors on the dendrite of the post-synaptic nerve cell
What is an excitatory synapse
causes a slight depolarization of the second cell (receptor opens to let Na+ in), called an excitatory postsynaptic potential (EPSP)
What is an inhibitory synapse
causes a slight hyperpolarization of the second cell (the receptor opens a receptor that allows Cl- in), called an inhibitory postsynaptic potential (IPSP)
Spatial summation
number and type of synapses on its dendrites
Temporal Summation
rate at which the presynaptic neuron fires
What two factors depend of if a postsynaptic cell reaches the threshold
spatial and temporal summation
What is a neuromodulator?
something that alters the sensitivity of neurons
What is sensory perception
The ability to understand and interact with the environment using senses of sight, smell, hearing, taste, touch
What is a azimuth
the angular measurement between the sound source and a reference direction
What is the Nucleus magnocellularis
½ cochlear nuclei. Processes the timing of sound
Nucleus angularis function
processes sound intensity
Inferior colliculus function
region of the midbrain where the neurons create a map auditory space
what is the optic tectum
area of the brain responsible for visual localization and orientation of the head
What is long term potentiation
persistent strengthening of synapses that enables a long-lasting increase in synaptic transmission in a neuronal network.
What is long term depression
an activity-dependent reduction in the efficacy of neuronal synapses lasting hours or longer following a long patterned stimulus
What is synaptic remodeling
changes in the number of dendritic spines of the postsynaptic neuron, production of growth factors by glial cells (which modify the growth of dendrites and axons), and activation of CREB, which also produce structure changes of synapses
What is neurogenesis
process where new neurons are formed
what is deafferentation
when the sensory nerve is cliped or chemically blocked
Draw the stucture of a basic neuron and label
just do it
Why are neurons polarized
Nerve cells are polarized when unexpired
More negative inside the cell membrane
What is more concentrated inside the cell
K
is there net movement of K across the membrane?
nah
Describe an action potential
Local depolarization of membrane opens voltage-sensitive sodium gates at neighboring points
This causes an action potential to travel down the axon
action potential occurs when the membrane potential of a specific cell rapidly rises and falls
Can you describe, generally, how a barn owl localizes sound? The neural pathways involved in timing and intensity of sound?
arn owl can detect the position of a prey item in complete darkness
Sensory perception begins with organization of sensory structures
Limit (tuned to) detection of stimuli
Pattern of feathers on face of owl and organization of its ears that allow it to determine the spatial location of prey without visual inputs
Owl uses difference of arrival times of sound to its two ears and difference in sound intensity between the two ears to determine the horizontal & vertical position of a sound stimulus
Ex. A noisy mouse
Information about timing of sound & sound intensity between ears travels as impulses in the Auditory nerve to the central nervous system
Axons in auditory nerve on each side of the head send a branch to two cochlear nuclei – the nucleus magnocellaris, which processes the timing of sound & the nucleus angularis, which processes sound intensity
Information relayed to external nucleus of the inferior colliculus, a region in the mid brain, where the neurons literally create a map auditory space
Specific neuron in the inferior colliculus responds maximally to specific binaural difference in the arrival of sounds
Auditory map space then relayed to the optic tectum (area of brain responsible for visual localization and orientation of head)
Can you describe habituation and sensitization in Aplysia?
When sea slug moves across the ocean bottom, its gills are spread and its siphon (used for exertion) is extended If siphon is touched by predator
1)stimulus to skin stimulates sensory neurons on the skin
2) facilitiating interneurons is stimulated that synapses on the azon terminal of the sensory neuron from the siphon skin
3) Serotonin realsease from facilitating neuron
4) increase cAMP
5) cAMP causes closing of K channels which prolongs depolarization
6) more Ca enters the axon terminal as usual
7) increased release of NT by sensory neuron
8) increased firing rate of gill motor neuron
How are memories stored?
Brain regions operate in networks – organization of these changes when an animal learns (memories are formed)
Synapse number and strength correspond to strength of mem
What is the duration of a short term memory
minutes or hours
What is the duration of an intermediate - term memory
weeks, months or years
How long do long term memories last
weeks, months, years, decades