Elixirs

Question 1

These are clear, sweetened hydroalcoholic solutions.

Answer 1

Elixirs

Question 2

Elixirs usage

Answer 2

for oral use and are usually flavored to enhance their palatability

Question 3

Elixirs. Non-Medicated Vehicles: Synonyms and Percentage of Alcohol

Answer 3

Iso or Low-Alcoholic Elixir and High-Alcoholic Elixir

Question 4

%ROH Iso-alcoholic Elixir

Answer 4

8 - 10%

Question 5

%ROH High Alcoholic Elixir

Answer 5

75-78%

Question 6

Elixirs

Answer 6

Not suitable for children and adults who avoid alcohol

Question 7

T/F. Elixirs are less sweet and less viscous - less effective in masking unpleasant API tast than syrups.

Answer 7

True

Question 8

Why hydroalcoholic?

Answer 8

water- soluble and alcohol- soluble API’s remain in solution better

Question 9

Alcohol Concentration

Answer 9

depends on the amount of API which are water- insoluble, if higher then alcohol concentration is also higher

Question 10

Alcohol concentration that is self preserving

Answer 10

10%-12%

Question 11

Adjunct Solvents

Answer 11

glycerin
propylene glycol

Question 12

viscosifiers and slows rate of filtration

Answer 12

Adjunct Solvents

Question 13

Sweetening Agent

Answer 13

sucrose (slightly soluble in ROH), sorbitol, glycerin, artificial sweeteners ie. saccharin

Question 14

Stabilizers

Answer 14

+ citric acid in Neomycin Elixir to adjust pH
+ Disodium EDTA to sequesteir heavy metals that decompose antibiotics

Question 15

Filtering Agent

Answer 15

Talc

Question 16

Spirits, Benzoic acid

Answer 16

Preservatives of Elixir