Elimination Review Flashcards
1
Q
List the mechanism steps for. E1 reactions
A
- Acid protonates most basic molecule in the reactants, converting hydroxyl group to water on alcohol
- Water leaves alcohol to leave behind a carbocation
- A base in the reaction mixture removes a proton from a beta carbon forming an alkanes
2
Q
E1 reaction uses Ziatsev’s rule t, what does this mean?
A
The major product will be the most substituted molecule
3
Q
What acid is often used to catalyze the dehydration of alcohol?
A
Sulfric acid
4
Q
Which degree of alcohol will be the most likely to undergo E1 reactions
A
Tertiary alcohol
5
Q
What types of alcohols are used to undergoSn2/E2 reactions?
A
Primary alcohols
6
Q
What kinds of nucleophile be used in nucleophilic substitution with alcohols?
A
Weak, basic nucleophile such as I- or Br-. Because moderately and strongly basic nucleophiles basic would be protonated
7
Q
What kind of substitutions do tertiary and secondary alcohols undergo?
A
SN1 reactions
