Electrolytes pt 3 Flashcards
Hypermagnesia is magnsium above?
2.5
Oral ingestion of laxatives, enemas, infusion, and renal insufficiency can all cause?
Hypermagnesia
What is the most common clinical feature of hypermagnesium?
Neuromuscular toxicity
Nausea, flushing, headahce, lethargy, drowsiness, and decreased DTRs occur at what level of magensium?
4-6
Somnolence, hypocalcemia, absent DTRs, hypotension, bradycardia, and EKG changes occur at what level of magnesium?
6-10
Muscle paralysis –> flaccid quadriplegia, apnea, respiratory failure, complete heart block and cardiac arrest occur at what magnesium levels?
>10
How do you diagnose hypermagnesia?
Magnesium level
BMP
EKG
What EKG changes will there be with hypermagnesia?
Diminished conduction
Widened QRS
Prolonged PQ
How do you treat hypermagnesia?
Stop offending agent, add diuretic maybe
Calcium gluconate is given IV - to help stabilize cardiac membrane
Hemodialysis if severe + renal impairment
Hypomagnesia occurs below?
1.8
What is the most common causes of hypomagnesia?
Chronic diuretic therapy (loop and thiazide)
Chronic alcoholism
Chronic diarrhea
Chronic PPI usage.
Tetany - positive Trousseau and chovstek sign, muscle spasm, seizures, involuntary movements are neurologic findings of what?
Hypomagnesia
What EKG findings are associated with hypomagnesia?
Widening of QRS, peaked T waves
Prolonged PR interval, QRS widening and diminished T wave (more severe)
Frequent PACs and PVCs - ventricular arrythmias.
Patients with hypomagnesia usually have concurrent?
Hypokalemia and hypocalcemia.
Can’t determine where your hypomagnesia is coming from. What test should you do?
24 hour urine magneisum excretion or fraction excretion of magnesium to help differentiate between GI and renal losses.
Treatment of severe symptoms like tetany, arrythmias, or seizures due to hypomagnesium should be treated with what?
IV magnesium sulfate
Continuous cardiac monitoring
Treatment of asymptomatic or minimal symptoms of hypomagneisum should be treated with?
Oral replacement - magnesium chloride or magnesium oxide - diarrhea major effect.
Malignancy such as ectopic secretion of PTH by tumor, multiple myeloma, and bone mets can cause what?
Hypercalcemia
Hyperparathyroidism, MEN, hyperthyroidism, pheochromocytoma, and adrenal insufficiency can cause?
Hypercalcemia
Granulomatous disease such as sarcoidosis, TB, histoplasmosis, Berylliosis and coccidiomycosis can cause what?
Hypercalcemia