Electrical signalling in neurons Flashcards
1
Q
First neurotransmitter to be described
A
Acetylcholine
2
Q
Gap junctions
A
Used by some cells in the brain. Fast transmission but no control of direction
3
Q
How is ACh mde
A
Choline acetyltransferase. Acetyl-coA and choline.
4
Q
How is the ACh signal terminated
A
Acetylcholinesterase
5
Q
Delay between preS Ca2+ influx and postS response
A
200microseconds
6
Q
Delay between AP arriving at preS terminal and change in postS potential
A
1 millisecond
7
Q
Quanta
A
End plate potentials (EPP) made up of multiple miniature EPPS (MEPPS)
8
Q
What are the SNARE proteins
A
Synaptotagmin, syntaxin, synaptobrevin, SNAP-25
9
Q
How are SNARE proteins cleaved
A
Clostridial toxins: BoTX (botulinum toxin) and TeTX (tetanus)
