Intro to NS II

Question 1

What is the name of the model for the NS

Answer 1

Four state model (sensory, cognitive, state, motor)

Question 2

How is memory stored?

Answer 2

Synaptic connection strengths of neural circuits

Question 3

What are 5 neuronal excitation motifs

Answer 3

Convergent, divergent, feedforward, feedback, recurrent (lateral)

Question 4

What are 2 neuronal inhibitory motifs

Answer 4

Feedforward, feedback

Question 5

What is the name given when two inhibitory neurons are next to each other

Answer 5

Disinhibition

Question 6

What is the synaptic density of the brain

Answer 6

10^9 per microlitre

Question 7

How much energy does it cost to move 1 H+ across the membrane

Answer 7

338 kJ/mol

Question 8

What blocks Na/K pumps

Answer 8

Digitalis

Question 9

What does Ek mean?

Answer 9

Potassium equilibirium gradient

Question 10

What is the equilibrium potential?

Answer 10

Electrical force = chemical (diffusional) force

Question 11

What are the two different types of change in membrane potentials?

Answer 11

Graded (post-synaptic potential) and sharp (AP)

Question 12

What is the Boltzmann distribution?

Answer 12

Allows you to calculate the various energies of different populations of particles at equilibrium. Ratio of # of particles: N1/N2. Different energies: u2-u1

Question 13

What is kT?

Answer 13

The energy of a single molecule

Question 14

What does the Nernst equation do?

Answer 14

Convert #s of individual entities N into concentrations C and single particle energies u into molar energies U

Question 15

What is RT?

Answer 15

Thermal energy per mole

Question 16

What is the Nernst equation?

Answer 16

Potential where there is no net flow of ions

Question 17

What is capacitance?

Answer 17

Ability of a body to store electrical charge

Question 18

How do we work out the resting potential?

Answer 18

Itot=O, Vrev.. (steady state, not equilibrium and net current = 0)