Effect Of Recreational Drugs Flashcards
What is a recreational drug?
Taken and used in the absence of medical grounds but are taken for pleasure and enjoyment
What is the general effect of recreational drugs on transmission in the CNS
drugs hijack the rewards system and produce pleasurable feelings without any adaptive function
What does cocaine block?
The binding site
What does cocaine stop?
The reuptake of dopamine back into the presynaptic receptors
What does more dopamine than usual in the reward pathway lead to?
Feelings of euphoria
What happens over time to the brain?
It reacts to the over stimulation of dopamine and reduces the number of receptors on the post synaptic neuron
What does it mean if there is a reduce of receptors on the post synaptic neuron?
More dopamine will be required to stimulate the postsynaptic neuron
Supporting evidence? EFFECT OF RECREATIONAL DRUGS
Recreational drugs create excess dopamine to give a ‘high’.
Hard to study? EFFECT OF RECREATIONAL DRUGS
Can’t study the mode of action of recreational drugs at the synaptic level as brain scanning techniques need to be more sophisticated