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hemato > eds > Flashcards

eds Flashcards

1
Q

Adriamycine ()

A
  • H in RCHOP
  • Anthracycylines
  • inhibiteur de la topoisomérase so less replication
  • effets au coeur
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2
Q

vincristine ()

A
  • O (oncovin) in RCHOP
  • Alkloid vinca
  • inhibiteur du fuseau mitotique
  • neuropathie
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3
Q

bléomycine

A
  • bris d’ADN

- fibrose pulmonaire

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4
Q

cyphlophosphamide ()

A
  • Agents alkylant
  • ponds dans l’ADN nuisant à la réplication
  • cyctite hémmoragique
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5
Q

cytarabine

A
  • analogue pyramidine qui inhibe synthèse ADN

- toxicité cérébelleuse et conjonctive

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6
Q

Fludarabine

A
  • analogue purines

- anémie hémolytique autoimmune

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7
Q

Rituximab ()

A
  • AC monoclaonaux lient CD20 des lympho
    = apoptose et cytotoxicité
  • rxn infusionelle (allergique)
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8
Q

Prednisone ()

A
  • P in RCHOP
  • corticostéroides
  • lymphotoxique
  • +++ ES
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9
Q

traitement pour lymphome hodgkin

A

ABVD + radio (si stade avancé)

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10
Q

traitement lymphome folliculaire

A

watch and wait , radiotheapi, agents al;kylansts, AC mono

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11
Q

traitement lymphome diffus à grandes cellules B (LNH)

A

R-CHOP

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12
Q

traitement LMC

A

Imatinib (gleevec)
D,N,B’P inib
greffe de SC

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13
Q

traitement LMA

A

si mutation FLT-3 = inhibiteur de FLT-3 (midostaurin)

si mutation FAB M3 (promyélocytaire) = ATRA

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14
Q

what helps with lyse tumorale?

A

allopurinol et hydratation

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15
Q

explain: immunothérapie

A

induce sys immuniatire (AC)

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16
Q

explains: chekpoint inhibitors

A

proteins de surface disent de ne pas tuer la cellules - Ac contre eux
LIKE PD ON SURFACE

17
Q

explain: CAR-T cells

A

cells taken out and given more properties

18
Q

explains: thérapie ciblée

A

cibler portion of signalisation (ex: gleevex, inhibitors de TK)

19
Q

translate:

mucite, alopécie, dysgueusie

A 
mucite = ulcers bouche 
alopécie = hair
dysgueusie = metal taste

hemato (5 decks)

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