Ed's Cardiac Output Lecture / Final Exam Prep Flashcards

1
Q

Cardiac Output

Formula ?

A
C.O      =  HR           X   SV
ml/min = beats/min X ml/beat
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2
Q

Cardiac Output (resting range)

A

4 - 8 L/m

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3
Q

6 Factors affecting Cardiac Output

MOBGAP

A
  • Metabolic rate
  • Oxygen demand
  • Body size / type
  • Gender
  • Age
  • Posture
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4
Q

The most potent determinate of cardiac output is

A

metabolic oxygen demand

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5
Q

5 Things that increase metabolism:

A
  • exercise
  • sepsis
  • strong emotion
  • trauma/surgery
  • temperature
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6
Q

C.O. of a female Vs. C.O. of a male?

A

female = 10% lower than a male of the same body size

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7
Q

In general, females have ____ skeletal muscle mass than males.

A

Smaller

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8
Q

How do we adjust for individual differences??

A
  • Calculate cardiac index!
  • Adjusts C.O. to a
    defined measurement
    Of body tissue
    (BSA)
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9
Q

Cardiac Index formula ?

A

C.O. / BSA

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10
Q

Normal adult C.I. range?

A

2.5 - 4.2 L/min/m2

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11
Q

How do we calculate BSA??

A

(w^.425)(H^.725)(.007184)

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12
Q

Advantages of CI ?

A

Normalizes cardiac output relative to body surface area

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13
Q

Disadvantages of CI ?

A

The relationship of metabolism to surface area can be very different from patient to patient

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14
Q

When is CI at its highest?

A

Childhood

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15
Q

Neonates may have

A

X3 the CI as an adult

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16
Q

when a person stands up, what happen?

A

C.O. decreases

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17
Q

S.V. formula =

A

C.O. / HR X1000

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18
Q

DO2 (delivery) formula=

A

CaO2 X C.O. X 10

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19
Q

PVR formula =

A

80 X (MPAP-PAWP) /C.O.

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20
Q

SVR formula =

A

80 X (MAP - RAP) / C.O.

21
Q

Stroke volume is a function of:

A

A. Preload (EDP)
B. Afterload (Pa)
C. Contractility

22
Q

Normal S.V. =

A

60 - 100 ml/beat

23
Q

E.F. Formula =

A

S.V. X 100 / EDV

24
Q

Normal E.F. =

25
Frank-Starling Law | describes what?
relationship between SV and cardiac performance
26
Preload definition = LVEDP y = Press X = Volume
``` the amount of -myocardial fiber stretch &/or - amount of volume in the ventricle at the end of diastole ```
27
Afterload definition =
resistance, impedance, pressure the ventricles must overcome | To eject its blood volume
28
Clinically the most sensitive measure of afterload is ?
SVR/PVR
29
SVR formula =
(MAP-RAP) X 80 _________________ C.O.
30
PVR formula =
(MPAP - PAWP) X 80 _________________ C.O.
31
What has an inverse relationship to afterload ?
Afterload
32
Inotrophism definition ?
inherent property of shortening of the myocardial | muscle fibers, apart from preload
33
What pathologies invalidate that the RV C.O. and LV C.O. are equal ?
- Intra-cardiac shunts | - Reguritant lesions
34
3 Invasive techniques to measure C.O. ?
Fick Method Dye dilution Thermal dilution
35
2 Non Invasive techniques to measure C.O. ?
Doppler | Bioimpedance
36
3 requirements for the Fick Principle?
- Arterial sample - Mixed venous sample - Spirometer
37
Fick Principle measures what ?
1. total O2 uptake per minute 2. amount into each 100 cc blood
38
The Fick method for cardiac output determination equation ?
C.O. (Q) = VO2 ____________ CaO2 - CvO2 X 10
39
“Gold standard” for measuring CO is ?
Thermodilution
40
What are the two methods of thermodilution that are available:
1) bolus thermodilution | 2) continuous cardiac output (CCO)
41
Catheter in the pulmonary artery monitors change in temperature of passing blood after a bolus of room temperature saline is deposited into the right atrium.
Thermodilution Method
42
In thermodilution process, the injectate port should be in ?
``` SVC or IVC or RA ```
43
In thermodilution process, the thermistor to monitor the blood's temperature is located near the catheter's distal tip, which should lie in ?
PA
44
to calculate the area beneath the curve. This area is | inversely proportional to what ?
C.O.
45
Small area under the curve =
higher C.O.
46
Large area under the curve =
lower C.O.
47
In bolus thermodilution, the CO curve is | displayed on the monitor and validates
Correct Injection technique
48
The accuracy of the thermodilution method depends on several assumptions:
1) Blood and injectant have mixed adequately. 2) Blood flow is forward. 3) Baseline temperature in the PA is steady. 4) Appropriate technique is used.