eczema and contact dermatitis

Question 1

what are the three pathophysiologic factors in atopic dermatitis?

Answer 1

1. immune dysfunction
2. environment
3. genetics

Question 2

Which criteria must be present in order to diagnose atopic dermatitis?

Answer 2

1. Pruritus
2. Relapsing or chronic dermatitis
3. Age specific patterns and typical morphology
   -face, neck, extensors in infants and children
   -flexural lesions at any age

Question 3

Which areas of the skin are typically NOT involved in atopic dermatitis ?

Answer 3

1. genitals (diaper area in babies)
2. inguinal folds
3. axillae

Question 4

Characteristic area of involvement of atopic dermatitis in infants/young children?

Answer 4

face and extensor arms/legs

Question 5

Characteristic area of involvement of atopic dermatitis in older children?

Answer 5

trunk, flexural extremities, neck (especially anterior aspect), antecubital fossa, popliteal areas, breasts/nipples

Question 6

Characteristic area of involvement of atopic dermatitis in adults?

Answer 6

face (especially eyelids), “dirty neck”, lichenification

Question 7

Difference in reaction onset between ACD and ICD?

Answer 7

ICD: immediate

ACD: 48-72 hours

Question 8

path findings in biopsy consistent with ACD?

Answer 8

eosinophilic spongiosis and lymphocytes