Eczema Flashcards

1
Q

What is eczema also known as?

A

Atopic dermatitis

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2
Q

What areas does it commonly affect?

A

Flexural areas

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3
Q

What is the definition of atopic eczema?

A

Itchy skin condition in the last 12 months plus 3 of the following

Onset before age 2
History of flexural involvement
History of generally dry skin
History of other atopic disease

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4
Q

What is spongiosis?

A

Intercellular oedema within the skin

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5
Q

What is acanthosis?

A

Thickening of the epidermis

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6
Q

What gene is associated with atopic eczema?

A

Filaggrin gene

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7
Q

What is the pathogenesis of eczema?

A

Genetics
Environmental factors
Epidermal barrier dysfunction

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8
Q

What are the clinical features of eczema?

A

Itch

Distribution in flexures, face, hands and feet

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9
Q

What are the acute changes of eczema?

A
Pruritis 
Eyrthema 
Scale 
Papules 
Vesicles 
Exudate, crusting
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10
Q

What are the chronic changes of eczema?

A

Lichenification
Plaques
Fissuring

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11
Q

What are some of the external causes of eczema?

A

Contact dermatitis
Lichen simplex
Photoallergic or photo aggravated eczema

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12
Q

What are some of the internal types of eczema?

A
Atopic 
Discoid
Venous 
Seborrhagic dermatitis 
Pompholyx
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13
Q

What type of reaction is allergic contact dermatitis?

A

Type 4 hypersensitivity

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14
Q

What can cause irritant contact dermatitis?

A

Friction
Cold
Over exposure to water
Chemicals (acids, detergents, solvents)

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15
Q

Who are commonly affected by irritant contact dermatitis?

A

Hairdressers
NHS staff
Cleaners
Nappy rash

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16
Q

What test is used to test for type 4 hypersensitivity?

A

Patch testing

17
Q

What is a common name for seborrhagic dermatitis in children?

A

Cradle cap

18
Q

What is the cause of seborrhagic dermatitis?

A

Overproduction of malassezia yeast

19
Q

What are the signs of seborrhagic dermatitis?

A

Red, sharply marginated lesions covered with greasy looking scales

20
Q

What is the treatment for seborrhagic dermatitis?

A

Topical anti-yeast (ketoconazole)

21
Q

What is the appearance of discoid eczema?

A

Circular plaques of eczema

22
Q

What are the signs of pompholyx/vesiular eczema?

A

Intensely itchy

Common on palms and soles

23
Q

What is the appearance of asteatotic eczema?

A

Cracked and scaly

Very dry skin

24
Q

What is the treatment for asteatotic eczema?

A

Emollients

25
Q

Where is a common area affected by venous eczema?

A

Ankle and lower leg

26
Q

What is a resolution for venous eczema?

A

Compression stockings

27
Q

What are the clinical symptoms of eczema herpeticum?

A

Fever, often unwell
Itchy clusters of blisters and erosions
Swollen lymph glands

28
Q

What causes eczema herpeticum?

A

Herpes simplex 1 and 2

29
Q

What is the general treatments for eczema?

A

Emollients
Soap substitutes
Intermittent topical steroids
Calcineurin inhibitors

30
Q

What are some of the treatments for severe eczema?

A

UV light

Immunosuppression