Eating Disorders Flashcards

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1
Q

Case 1: 18 yo female presents with 5 mo h/o wt loss

  • she began reducing the fat in her diet - lost 22 lbs and now weighs 95 lbs
  • she hardly eats has a BM 4-5 days, runs 4 miles q day and does 100 sit ups, LMP was 6 mo, not sexually active
  • She constantly feels cool and is dizzy upon standing, hair is dry, feels bloated after meals, she still thinks she is too large and she doesn’t think she has a problem
  • DSM 5 criteria?
A
  • classic example of anorexia nervosa
  • DSM-5 criteria:
    restriction of energy intake relative to requirements, leading to sig. low body wt in context of age, sex, developmental trajectory and physical health
  • fear of wt gain
  • severe body image disturbance in which body image is predominant measure of self worth with denial of the seriousness of the illness
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2
Q

Subtypes of anorexia nervosa?

A
  • restricting: restriction of intake to reduce wt
  • binge eating/purging: may binge and/or purge to control wt
    considered anorexic if she/he is 15% below ideal body wt
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3
Q

Signs and sxs of anorexia nervosa?

A
  • dry skin
  • cold intolerance
  • blue hands and feet
  • constipation
  • bloating
  • delayed puberty
  • primary or secondary amenorrhea
  • fainting
  • orthostatic hypotension
  • lanugo hair: fine hair - body’s response to malnourishment, keeping warm
  • scalp hair loss
  • early satiety
  • weakness, fatigue
  • short stature
  • osteopenia
  • breast atrophy
  • atrophic vaginitis
  • pitting edema
  • cardiac murmurs
  • sinus brady
  • hypothermia
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4
Q

Case 2: 20 yo female - presents for eval of hematemesis - admits to self-induced vomiting for past 3 yrs, 62” tall, 140 lbs - gorges and vomits 3-5x week, uncontrollable eating binges, feels guilty, smokes 1 pack of cigs a day, gets drunk weekly - binge drinks, irregular menses, hasn’t lost wt. Characteristic of? DSM-V criteria?

A
  • bulimia
    A. recurrent of binge eating. An episode of binge eating is characterized by both of the following:
    1. eating in a discrete period of time, an amt of food that is definitely larger than what most individuals would eat
    2. a sense of lack control over eating during the episode
    B. recurrent inappropriate compensatory behaviors in order to prevent wt gain, such as self-induced vomiting, misuse of laxatives, diuretics, other meds, fasting, or excessive exerciese
    C. binge eating and inappropriate compensatory behaviors both occur, on average at least 1x a week for 3 months
    D. self eval is unduly influenced by body shape and wt
    E. the disturbance doesn’t occur exclusively during periods of anorexia nervosa
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5
Q

Signs and sxs of bulimia?

A
  • mouth sores
  • pharyngeal trauma
  • dental caries
  • heartburn, chest pain
  • esophageal rupture
  • impulsivity: stealing, ETOH abuse, drugs/tobacco
  • muscle cramps
  • weakness
  • bloody diarrhea
  • bleeding or easy bruising
  • irregular periods
  • fainting
  • swollen parotid glands (from overuse)
  • hypotension
  • russell’s sign: callouses on knuckles
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6
Q

Binge eating disorder?

A
  • eating, in a discrete period of time, an amt of food that is larger than most people would eat in similar period
  • occurs 2 days/week for 6 month duration
  • assoc with lack of control and with distress over the binge eating
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7
Q

Binge eating disorder criteria?

A

must have at least 3 of 5:

  • eating much more rapidly than normal
  • eating until uncomfortably full
  • eating large amts of food when not feeling physically hungry
  • eating alone b/c of embarrassment
  • feeling disgusted, depressed or very guilty about overeating
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8
Q

Eating disorder, NOS - DSM-5 criteria?

A
  1. all criteria for anorexia nervosa except has regular menses
  2. all criteria for anorexia except wt still in normal range
  3. all criteria for bulimia except binges less than 2x a week for less than 3 months
  4. pts with normal body wt who regularly engage in inappropriate compensatory behavior after eating small amts of food (self induced vomiting after eating 2 cookies)
  5. a pt who repeatedly chews and spits out large amts of food without swallowing
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9
Q

Epidemiology of eating disorders?

A
  • anorexia: incidence rates have increased in past 25 years, affects 1% of adolescent females, rates for men only 10% of those for women, seen in pts as young as 6
  • bulimia: occurs in 1-5% of high school girls, and as high as 19% in college women
  • eating disordre NOS: occurs in 3-5% of women b/t ages 15-30 in western countries, as minority culture groups assimilate into american society - rates increase
  • binge eating disorder: occurs more commonly in women, depening on pop surveryed, can vary from 3%-30%
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10
Q

Assoc psych conditions with Eating disorders?

A
  • anxiety disorders
  • OCD
  • personality disorders
  • substance abuse
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11
Q

Pathogenesis of eating disorders?

A
  • no consensus on precise cause

- combo of psychological, biological, family, genetic, enviro and social factors

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12
Q

Screening tools - SCOFF questionnaire?

A
  • do you make yourself Sick b/c you feel uncomfortably full?
  • do you worry you have lost Control over how much you eat?
  • have you recently lost more than 14 lbs (One stone) in a 3 month period?
  • Do you believe yourself to be Fat when others say you are too thin?
  • Would you say that Food dominates your life?
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13
Q

Screening tool - eating disorder screen for primary care (ESP)?

A
  • are you satisfied with your eating patterns? (no is abnormal)
  • do you ever eat in secret? (yes is abnormal)
  • does your wt affect the way you feel about yourself? (yes is abnormal)
  • have any members of your family suffered with an eating disorder? (yes is abnormal)
  • do you currently suffer with or have you ever suffered in the past with an eating disorder? (yes is abnormal)
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14
Q

Impt hx ?s to hit?

A
  • max ht and wt
  • exercise habits: intensity, hrs/week
  • stress level
  • habits and behaviors: smoking, ETOH, drugs, sexual activity
  • eating attitudes and behaviors
  • ROS
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15
Q

PE findings in anorexia?

A
  • vital signs to include orthostatics
  • skin and extremity eval: dryness, bruising, lanugo
  • cardiac exam: bradycardia, arrhythmia, MVP (heart muscle shrinks but valves don’t)
  • abdominal exam
  • neuro exam: eval for other causes of wt loss or vomiting (brain tumor)
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16
Q

PE findings in bulimia?

A
  • all previous elements seen in anorexia plus:
    parotid gland hypertrophy
    erosion of the teeth enamel
17
Q

Lab assessment in Eating disorders?

A
  • CBC: anemia
  • lytes, BUN/Cr
  • Mg, PO4, Calcium, k+
  • albumin, serum protein
  • B-HCG
  • UA: specific gravity
  • thyroid fxn tests
  • serum prolactin
  • FSH
  • bone density
18
Q

DDx of eating disorder?

A
  • new onset diabetes
  • adrenal insufficiency
  • primary depression with anorexia
  • IBD
  • abdominal masses
  • CNS lesions
19
Q

Complications of eating disorder?

A
- fluid and lytes imbalance:
hypokalemia
hyponatremia
hypochloremic alkalosis
elevated BUN
inability to concentrate urine
decreased GFR
ketonuria
20
Q

Complications - osteopenia? Tx?

A
  • one of the most severe complications
  • difficult to reverse
  • tx:
    wt gain
    1200-1500 mg/day of elemental Ca2+
    multivitamin w/ 400 IU vit D
    consider estrogen/progesterone replacement
21
Q

Complications - amenorrhea? Tx?

A
  • secondary amenorrhea affects more than 90% of pts with anorexia
  • caused by low levels of FSH and LH
  • menses resumes w/in 6 months of achieving 90% IBW
22
Q

Complications - cardiac changes? When is risk of heart failure the greatest?

A
  • MVP: occurs in 32-60% of pts with anorexia
  • long QT: one study found as many as 33% of pts:
    independent marker for arrhythmia
    immediate attention if pt is bradycardic and underwt as well
  • risk of heart failure is greatest in first 2 weeks of refeeding: reduced cardiac contractility and refeeding edema, slow referring, repletion of K+, avoidance of Na+ intake
23
Q

non pharm Tx of anorexia?

A
  • CBT: emphasizes the relationship of thoughts and feelings to behavior
  • limited efficacy
  • interdisciplinary care team: medical provider, dietician with experience in eating disorders, mental health professional
24
Q

med use for anorexia?

A
  • overall, disappointing results
  • effective only for tx co-morbid conditions of depression and OCD
  • anxiolytics may be helpful b/f meals to suppress the anxiety assoc with eating
  • case reports in the literature supporting use of olanzapine (zyprexa) - atypical antipsychotic
25
Q

When should pt with anorexia be hospitalized?

A
  • severe malnutrition (less than 75% IBW)
  • dehydration
  • lyte disturbances
  • cardiac dysrhymia
  • arrested growth and development
  • physiologic instability
  • failure of outpt tx
  • acute psychiatric emergencies
  • comorbid conditions that interfere with tx of the ED
26
Q

Nutrition goals in anorexia tx?

A
  • goal: regain to goal of 90-92% of IBW
  • inpt tx varies by facility:
    oral liquid nutrition
  • NG tube feedings
  • gradula caloric increase with “regular” food
  • parenteral nutrition (IV feeding) rarely indicated
27
Q

Outcome for pts with anorexia?

A
  • 50% good outcome: return of menses and wt gain
  • 25% intermediate outcome: some wt regained
  • 25% poor outcome:
    assoc with later age onset
    longer duration of illness
    lower min. wt
    overally mortality rate: 6.6%
28
Q

Bulimia - tx?

A
  • CBT: effective
    pharm: high success rate
  • fluoxetine (prozac) SSRI studies reveal up to a 67% reduction in binge eating and 56% reduction in vomiting
  • TCAs
  • topiramate (topamax - antiepileptic) reduced binge eating by 94% and average wt loss of 6.2 kg
  • ondansetron (zofran) 24 mg/day for nausea

***better outcome with tx than anorexia

29
Q

Tx of binge eating disorder?

A
  • CBT

- pharmacotherapy

30
Q

What is the female athlete triad? Who is at risk?

A
  • eating disorders
  • stress fractures
  • amenorrhea
  • at risk:
    appearance related sports
    high performance sports
31
Q

What to look for if suspecting female athlete triad?

A
  • wt
  • HR of 40-50
  • hypotension
  • parotid swelling
  • poor dentition
  • overuse injuries, especially stress fractures
32
Q

Tx of the female athlete triad?

A

tx: multidisciplinary effort
- estrogen replacement: 3 yrs post menarche and older than 16 or if hx of stress fracture
- decrease energy expenditure
- nutritional consultation
- Ca and Vitamin D
- psychological counseling
- avoid NSAIDs