Eating Disorders Flashcards

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1
Q

What are the ICD-10 diagnosis criteria for AN?

A

Fear of weight gain
Endocrine resulting in amenorrhoea, loss of sexual interest F and potency M
Emaciated: >15% below expected weight or BMI<17.5
Deliberate weight loss with low food or high exercise
Distorted body image

*for 3m with absence of recurrent episodes of binge eating, preoccupation with eating/ craving to eat

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1
Q

What is Anorexia Nervosa?

A

an eating disorder characterised by deliberate weight loss, intense fear of fatness, distorted body image and endocrine disturbances

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2
Q

What are some potential causes of AN?

A
  • predisposing : genetics, FHx, sexual abuse, low self esteem, anapaestic personality, western pressures, bullying, stressful life events
  • precipitating : adolescence, puberty, criticism, occupation
  • perpetuating : starvation causing neuroendocrine changes, perfectionism, occupation, western society
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3
Q

What is the epidemiology of AN?

A

lifetime prevalence between 2-4%
more women (10 times more)
peak age onset - mid-adolescence

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4
Q

How does anorexia differ from bulimia?

A
  • significantly more underweight
  • more likely to have endocrine like amenorrhoea
  • no strong food cravings
  • no binge eating
  • compensatory weight loss behaviour (NOT purging)
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5
Q

How might you investigate AN?

A

FBC - normocytic, normochromic anaemia, low WCC, platelets
U&E - low K+ due to vomiting, low Na+ and K+ from laxatives, low phosphate and magnesium
LFT - loss of proteins
lipids - hypercholestrolaemia
hormones - LH, FSH, Oestridiol TFT, cortisol
glucose - impaired tolerance as high
VBG
DEXA - from ED team
ECG - CVS abn. if low electrolytes

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6
Q

What are some complications of AN?

A

metabolic: hypokalaemia, hypoglycaemia, hyperchol.

endocrine: high cortisol, low TFT, low sex hormones

CVS: cardiac failure, arrhythmia, bradycardia

renal: failure, stones

neuro: seizures

haematology: iron def. anaemia

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7
Q

How might AN be managed?

A

risk assessment is vital
psychological treatment 6m (CBT-ED, family therapy, MANTRA)
aim for controlled weight gain
refeeding syndrome risk
hospitalisation if BMI<14 and psychiatric
medications for complications and depression
self help groups etc

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8
Q

What is refeeding syndrome?

A

results from food intake after prolonged starvation or malnourishment, caused by increased insulin release leading to phosphate, magnesium and potassium to move into cells, causing low levels in blood

*phosphate depletion causes reduction in cardiac activity leading to failure

** prevent by starting at 1200kcal/day then increasing every 5 days monitoring for oedema or tachycardia

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9
Q

What is Bulimia nervosa?

A

repeated episodes of uncontrollable binge eating followed by compensatory weight loss behaviours and overvalued ideas regarding ideal body shape/weight

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10
Q

Describe the vicious cycle of BN?

A

pt with BN due to strong cravings, feel guilty and undergo compensatory behaviours like purging, laxatives, exercising.

*leads to large weight fluctuations, reinforcing of the behaviours

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11
Q

What is the epidemiology of BN?

A
  • young women
  • equal socioeconomic
  • think this in men too!
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12
Q

What are the risk factors for BN?

A

FH, substance misuse, childhood obesity, abuse, parental obesity, bullying, profession

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13
Q

What other co-morbid psychiatric conditions may they have?

A

depression
anxiety
deliberate self harm
substance misuse
EUPD

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14
Q

What are the ICD-10 criteria for BN?

A
  1. behaviours to prevent weight gain: purging, starvation, laxatives, diabetics omiting insulin
  2. preoccupation with eating
  3. fear of fatness
  4. over-eating

*weight maybe normal

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15
Q

What are some complications which maybe seen O/E in BN?

A

Russell sign from inducing
BL parotid swelling
dental erosion

16
Q

What are the subtypes of BN?

A

purging type
non-purging type : exercise and starving post binge

17
Q

How does BN differ from AN?

A

normal weight or overweight
less endocrine
strong food cravings
recurrent binging
compensatory behaviours definitely

18
Q

What are some complications of the purging?

A

mallory weiss tears
dehydration
dental erosions
amenorrhoea
aspiration pneumonitis
hypokalaemia

19
Q

How might BN be managed?

A
  • antidepressants, treat complications, treat co-morbids
  • psychoeducation, interpersonal psychotherapy
  • food diary, self help
  • risk assessment
  • 50% fully recover compared to 20% in AN
20
Q

What signs might a GP see in a suspected case of ED?

A
  • Alopecia
  • Lanugo hair
  • Emaciation
  • Russel’s sign
  • Swollen parotids
  • Dental erosion
  • Bradycardia around 40bpm
  • Postural hypotension
  • Muscle weakness shown by sit ups, squad stand test
  • Dependent oedema
21
Q

What are some differentials for significant weight loss?

A

Intentional weight loss (disorder/deliberate)
Depression
Physical health - IBD, coeliac, malignancy, hyperthyroidism, infection