Ear, Nose and Throat Flashcards
audiometry
Quantify loss and determine nature
Pure tone audiometry
headphones at different frequencies and strengths in soundproofed room
pt indicates when sound appears and siappears
mastoid vibrator - bone conduction threshold
threshold at different frequencies plotted to give audiogram
Tympanometry
Measures stiffness of ear drum
- evaluates middle ear function
flat tympanogram - mid ear fluid or perforation
Shifted tympanogram - +/- mid ear pressure
Evoked response audiometry
auditory stimulus w measurement of elicited brain response by surface electrode
used for neonatal screening if otoacoustic emission testing negative
Otitis Externa
Presentation (otalgia)
- watery discharge
- itchy
- pain + tragal tenderness
Causes Moisture: e.g. swimming Trauma: e.g. fingernails Absence of wax Hearing aid
Organisms
Mainly pseudomonas
Staph aureus
Management Aural toilet w drops Betamethasone for non-infected eczematous OE Betamethasone w neomycin Hydrocortisone w gentamicin Acidifying drops
Malignant Otitis Externa
Life-threatening infection which can > skull osteomyelitis
90% pt diabetic (or other immunocompromisation)
Presentation
Severe otalgia which is worse @ night
Copious otorrhoea
Granulation tissue in the canal
Rx
Surgical debrdement
Systemic Abx
Bullous Myringhitis
Painful haemorrhagic blisters on deep meatal skin and TM.
Assoc. c¯ influenza infection
TMJ Dysfunction
Sx - otalgia (earache) - referred pain from auriculotemporal nerve
- facial pain
- joint clicking/popping
- teeth-grinding (burxism)
- stress (assw depression)
Signs
- joint tenderness exacerbated by lateral movement of open jaw
Ix - MRI
Mx - NSAIDs
- stabilising orthodontic occlusal prostheses
Otitis Media
Classification
Classification
Acute: acute phase
Glue ear / OME: effusion after symptom regression
Chronic: effusion > 3mo if bilat or > 6mo if unilat
Chronic suppurative OM: Ear discharge c¯ hearing
loss and evidence of central drum perforation.
Organisms
- Viral
- Pneumococcus
- Haemophilus
- Moraxella
Acute Otitis Media
Presentation Usually children post viral URTI Rapid onset ear pain, tugging @ ear. Irritability, anorexia, vomiting Purulent discharge if drum perforates
o/e
Bulging, red TM
Fever
Rx
Paracetamol: 15mg/kg
Amoxicillin: may use delayed prescription
Acute Otitis Media Compliciations
Intratemporal OME Perforation of TM Mastoiditis Facial N. palsy
Intracranial
Meningitis / encephalitis
Brain abscess
Sub- / epi-dural abscess
Systemic
Bacteraemia
Septic arthritis
IE
Otitis MEdia Externa (glue ear)
Presents
- inattention at school
- poor speech development
- hearing impairment
O/E - retracted dull TM
- fluid level
Ix - audiometry flat tympanogram
Rx - usually resovles spontaneously
- consider grommets if persistent hearing loss
> SE infections, tympanosclerosis
Chronic Suppurative OM
Presentation - painless discharge and hearing
O/E - TM perforation
Rx - aural toilet
- abx/steroids ear drops
Complications - cholesteatoma
Mastoiditis
Middle-ear inflam > destruction of mastoid air cells + abscess formation
Presentation - fever, mastoid tenderness, protruding auricle
Imaging CT
Rx - IV abx
- myringotomy +/- mastoidectomy
Cholesteatoma
Locally destructive expansion of stratified squamous epithelium within middle ear
Classification
- congenital
- acquired 2ndary to attic perforation in chronic suppurative OM
Presentation - Foul smelling white discharge - headache, pain - CN involvement > vertigo, deafness, facial paralysis
O/E - appears pearly white w surrounding inflammation
Mx - Surgery
Cholesteatoma Complications
Deafness (ossicle destruction)
Meningitis
Cerebral abscess
Tinnitus
Sensation of sound w/o external sound stimulation
Causes Specific Meniere’s Acoustic neuroma Otosclerosis Noise-induced Head injury Hearing loss: e.g. presbyacusis
General
↑BP
↓Hb
Drugs Aspirin Aminoglycosides Loop diuretics EtOH
Tinnitus History
Character: constant, pulsatile
Unilateral: acoustic neuroma
FH: otosclerosis
Alleviating/exacerbating factors: worse @ night?
Associations
Vertigo: Meniere’s, acoustic neuroma
Deafness: Meniere’s, acoustic neuroma
Cause: head injury, noise, drugs, FH
Tinnitus Examination Ix Mx
Examination
Otoscopy
Tuning fork tests
Pulse and BP
Ix
Audiometry and tympanogram
MRI if unilateral to exclude acoustic neuroma
Mx
Treat any underlying causes
Psych support: tinnitus retraining therapy
Hypnotics @ night may help
Vertigo
Causes
Illusion of movement
Cause
Peripheral/vestibular
- Meniere’s
- BPV
- Labyrinthitis
Central - Acoustic neuroma - MS - vertebrobasilar insufficiency/stroke head injury - inner ear syphilis
Drugs (central/ototoxic) Gentamicin Loop diuretics Metronidazole Co-trimoxazole
Veritogo Hx + Examination + tests
Hx
Is it true vertigo or just light-headedness?
> Which way are things moving?
Timespan
Assoc. symptoms: n/v, hearing loss, tinnitus, nystagmus
Examination and Tests Hearing Cranial nerves Cerebellum and gait Romberg’s +ve = vestibular or proprioception Hallpike manouvre Audiometry, calorimetry, LP, MRI
Meniere’s Disease
presentation
Dilatation of endolymph space of membranous labryrinth (endolymphatic oedema)
Presentation
- Attacks occur in clusturs + last up to 12 hours
- progressive SNHL (sensnorineural hearing loss)
- vertigo + N/v
- tinnitus
- aural fullness
Meniere’s Disease
Ix Rx
Ix - audiometry shows low-freq SNHL which fluctuates
Rx
Medical - vertigo, cyclizine, betahistine
Surgical - gentamicin instillation via grommets
- Saccus decompression
Vestibular Neuronitis/Viral labyrinthitis
Presentation
- following febrile illness (URTI)
- sudden vomiting
- severe vertigo exacerbated by head movement
Rx
- Cyclizine
- Improvement in days
Benign positional vertigo (BPV)
Displacement of otoliths in semicircular canals
- common after head injury
Presents
- sudden rotational vertigo for <30s
> provoked by head turning
- nystagmus
Causes
- idiopathic
- head injury
- otosclerosis
- post-viral
Dx - hallpike manoeuvre > upbeat torsional nystagmus
Rx
- self-limiting
- epley manoeuvre
- betahistine - histamine analogue
Conductive Adult Hearing Loss
Impaired conduction between auricle and round window
External canal obstruction
Wax
Pus
Foreign body
TM perforation
Trauma
Infection
Ossicle defects
Otosclerosis
Infection
Trauma
Inadequate eustachian tube ventilation of middle ear
Sensorineural Adult Hearing Loss
Defects of cochlrea, cochlear Nerve or brain
Drugs
- aminoglycosides
- vancomycin
Post-infective
- meningitis
- measles
- mumps
- herpes
Misc
- Meniere’s
- Trauma
- MS
- CPA lesion (acoustic neuroma)
- low B12
Acoustic Neuroma/Vestibular Schwannoma
Benign slow growing tumour of superior vestibular nerve
Acts as SOL > cerebellar pontine angle syndrome
assw NF2
Acoustic Neuroma/Vestibular Schwannoma
Presentation
Slow onset, unilat SNHL, tinnitus ± vertigo
Headache (↑ICP)
CN palsies: 5,7 and 8
Cerebellar signs
Acoustic Neuroma/Vestibular Schwannoma
Ix DDx Rx
Ix
MRI of cerebellopontine angle
>MRI all pts. c¯ unilateral tinnitus / deafness
PTA
Differential
Meningioma
Cerebellar astrocytoma
Mets
Rx
Gamma knife
Surgery (risk of hearing loss)
Otosclerosis
AD fixation of stapes at oval window F>M
Presents
- early adult life bilateral conductive deafness + tinnitus
- HL improved in noisy places - Willis paracousis
- worsened by pregnancy menstruation/menopause
Ix - PTA shows dip Caharts notch at 2kHz
Rx - hearing aid or stapes implant
Presbyacussis
Age related hearing loss
Presentation - >65y
- bilateral slow onset
- +/- tinnitus
Ix PTA
Rx - hearing aid
Congenital Hearing loss in Children
Conductive
Anomalies of pinna, external auditory canal, TM or ossicles.
Congenital cholesteatoma
Pierre-Robin
SNHL
AD - Waardenburgs: SNHL, heterochromia + telecanthus
AR
Alport’s: SNHL + haematuria
Jewell-Lange-Nielson: SNHL + long QT
X-linked - Alport’s
Infections: CMV, rubella, HSV, toxo, GBS
Ototoxic drugs
Perinatal causes of hearing loss
anoxia
cerebral palsy
kernicterus
infection - meningitis
Acquired causes of hearing loss in children
OM/OME
infection - meningitis, measles
head injury
Universal Neonatal Hearing Tests
Detection + Mx of hearing loss before 6mo improves language
Tests
- otoacoustic emissions
- audiological
Congenital Anomalies
1st and 2nd branchial arches form auricle while 1st
branchial groove forms external auditory canal.
Malfusion → accessory tags/auricles and preauricular pits, fistulae or sinuses.
Sinuses may get infected, mimicking a sebaceous
cyst.
Pinna Haematoma
Blunt trauma > subperichondrial haematoma
Can > ischaemic necrosis of cartilage + subsequent fibrosis > cauliflower ears
Mx - aspiration + firm packing to auricle contour
Exostoses
Smooth symmetrical bony narrowing of external canals
Bony hypertrophy due to cold exposure
- from swimming/surfind
Sx - ASx unless narrowing occludes > conductive deaf
Wax: Cerum Auris
Secreted in outer 3rd of canal to prevent maceration
Wax accumulation can > conductive deafness
Mx - suction under direct vision w microscope
- syringing after 1 wk softening wth oil
Tympanic Membrane Perforation
causes
OM
Foreign Body
Barotrauma
Trauma
Allergic Rhinosinusitis
Classification
- seasonal (hay-fever)
- perennial
T1HS IgE mediated inflam from allergen exposure > mediator release from mast cells
Allergens - pollen, house dust mites
Sx - sneezing, pruritis, rhinorrhoea
Signs - swollen, pale, boggy turbinates
- nasal polyps
Ix - skin prick testing to find allergens (not if prone to eczema
- RAST tests
Allergic Rhinosinusitis Mx
Allergen Avoidance
Regularly washing bedding (inc. toys) on high heat or
use acaricides.
Avoid going outside when pollen count high.
1st Line
Anti-histamines: cetirazine, desloratidine
Or, beclometasone nasal spray
Or, chromoglycate nasal spray (children)
2nd Line: intranasal steroids + anti-histamines
3rd Line: Zafirlukast
4rd Line: Immunotherapy
Aim to induce desensitisation to allergen
OD SL grass-pollen tablets → ↑ QOL in hay-fever
Injection immunotherapy
Adjuvants
Nasal decongestants: Pseudoephedrine, Otrivine
Sinusitis
Viruses → mucosal oedema and ↓ mucosal ciliary
actions → mucus retention ± 2O bacterial infection
Acute: Pneumococcus, Haemophilus, Moraxella
Chronic: S. aureus, anaerobes
Causes
Majority are bacterial infection 2O to viral
5% 2O to dental root infections
Diving / swimming in infected water
Anatomical susceptibility: deviated septum, polyps
Systemic Disease
PCD / Kartagener’s
Immunodeficiency
Sinusitis Sx, Imaging
Symptoms
Pain
Maxillary (cheek/teeth)
Ethmoidal (between eyes)
↑ on bending / straining
Discharge: from nose → post-nasal drip c¯ foul taste
Nasal obstruction/congestion
Anosmia or cacosmia (bad smell w/o external source)
Systemic symptoms: e.g. fever
Imaging
Nasendoscopy ± CT
Sinusitis Mx
Acute / Single Episode
Bed-rest, decongestants, analgesia
Nasal douching and topical steroids
Abx (e.g. clarithro) of uncertain benefit
Chronic / recurrent Usually a structural or drainage problem. Stop smoking + fluticasone nasal spray Functional Endoscopic Sinus Surgery If failed medical therapy
Sinusitis Complications
Mucoceles → pyoceles
Orbital cellulits / abscess
Osteomyelits – e.g. Staph in frontal bone
Intracranial infection
Meningitis, encephalitis
Abscess
Cavernous sinus thrombosis.
Nasal Polyps
Sites
Sx
Signs
M 40
Sites - Middle turbinates, middle meatus, ethmoids
Sx
- Watery anterior rhinorrhoea
- purulent post nasal drip
- Nasal obstruction
- sinusitis
- headaches
- snoring
Signs
- Mobile, pale, insensitive
Nasal polyp associations
Allergic / non-allergic rhinitis
CF
Aspirin hypersensitivity
Asthma
Single Unilateral Polyp
May be sign of rare sinister pathology
Nasopharyngeal Ca Glioma Lymphoma Neuroblastoma Sarcoma
Do CT and get histology
Nasal Polyp in children
Rare <10yrs old
Must consider neoplasms and CF
Mx Drugs Betamathasone drops for 2/7 Short course of oral steroids Endoscopic Polypectomy
Fractured Nose
Anatomy
- upper 1/3 of nose has bony support
- lower 2/3 and septum cartilaginous
Hx Time of injury LOC CSF rhinorrhoea Epistaxis Previous nose injury Obstruction
Consider facial #, check for
Teeth malocclusion
Piplopia (orbital floor #)
Fractured Nose
Ix - cartilaginous injury won’t show and radiographs don’t alter Mx
Mx
- exclude septal haematoma
- re-examine after 1 wk (decreased swelling)
- reduction under GA w post-op splinting best w/i 2 weeks
Septal Haematoma
Septal necrosis + nasal collapse if untreated
Cartilage blood supply comes from mucosa
Boggy swelling and nasal obstruction
Needs evacuation under GA c¯ packing ± suturing.
Epistaxis Causes
80% unknown
Trauma: nose-picking / #s
Local infection: URTI
Pyogenic granuloma
Overgrowth of tissue on Little’s area due to irritation or hormonal factors.
Osler-Weber-Rendu / HHT
Coagulopathy: Warfarin, NSAIDs, haemophilia, ↓plats,
vWD, ↑EtOH
Neoplasm
Epistaxis Initial Mx
Wear PPE
Assess for shock and manage accordingly
If not shocked
Sit up, head tilted down
Compress nasal cartilage for 15min.
If bleeding not controlled remove clots w suction or by
blowing and try to visualise bleed by rhinoscopy
Anterior Epistaxis
Usually septal haemorrhage: Little’s area / Kisselbach’s plexus Ant. Ethmoidal A. Sphenopalatine A. Facial A.
Insert gauze soaked in vasoconstrictotr + LA
Xylometazoline + 2% lignocaine
5min
Bleeds can be cauterised w silver nitrate sticks
Persistent bleeds should be packed with Mericel pack
Refer to ENT if this fails or if you can’t visualise
the bleeding point.
They may insert a posterior pack or take pt. to
theatre for endoscopic control.
Posterior/Major epistaxis
Posterior packing (+ anterior pack)
Pass 18/18G Foley catheter through the nose
into nasopharynx, inflate w 10ml water and pull
forward until it lodges.
Admit pt. and leave pack for ~48hrs.
Gold standard is endoscopic visualisation and direct control: e.g. by cautery or ligation.
Epistaxis After bleed
Don’t pick nose Sit upright, out of the sun Avoid bending, lifting or straining Sneeze through mouth No hot food or drink Avoid EtOH and tobacco
Osler-Weber-Rendu/HHT
AD 5 Genetic Subtypes
Features
- Telangiectasias in mucosae
Recurrent spontaneous epistaxis
GI bleed (usually painless)
- Internal telangiectasias and AVM
Lungs
Liver
Brain
Rarely
Pulmonary HTN
Colon polyps: may → CRC
Tonsilitis Sx Signs Organisms
Symptoms
Sore throat
Fever, malaise
Signs
Lymphadenopathy: esp. jugulodigastric node
Inflamed tonsils and oropharynx
Exudates
Organisms Viruses are most common (consider EBV) GAS: Pyogenes Staphs Moraxella
Tonsilitis Mx
Swabbing superficial bacteria is irrelevant and can →
overdiagnosis.
Analgesia: Ibuprofen / Paracetamol ± Difflam gargle
Consider Abx only if ill: use Centor Criteria
Pen V 250mg PO QDS (125mg TDS in children) or erythromycin for 5/7
NOT AMOXICILLIN → MACPAP RASH IN EBV
Centor Criteria
Guideline for admin Abx in acute sore throat/tonsilitis/pharyngitis
1 point for
- Hx of fever
- Tonsillar exudates
- Tender anterior cervical adenopathy
- No cough
Mx
0-1: no Abx (risk of strep infection <10%)
2: consider rapid Ag test + Rx if +ve
≥3: Abx
Tonsillectomy Indications
Recurrent tonsillitis if all the below criteria are met
Caused by tonsillitis
5+ episodes/yr
Symptoms for >1yr
Episodes are disabling and prevent normal
functioning
Airway obstruction: e.g. OSA in children
Quinsy
Suspicion of Ca: unilateral enlargement or ulceration
Tonsillectomy method + complications
Cautery or cold steel..
Complications Reactive haemorrhage Tonsillar gag may damage teeth, TMJ or posterior pharyngeal wall. Mortality is 1/30,000
Strep throat complications
Peritonsillar Abscess
Quinsy
Typically occurs in adults
Symptoms
Trismus
Odonophagia: unable to swallow saliva
Halitosis
Signs Tonsillitis Unilateral tonsillar enlargement Contralateral uvula displacement Cervical lymphadenopathy
Rx
Admit
IV Abx
I&D under LA or tonsillectomy under GA
Strep throat complications
Retropharyngeal Abscess
Rare
Presents
- unwell child w stiff, extended neck who refuses to eat + drink
- fails to improve w IV abx
- unilateral swelling of tonsil of tonsil + neck
Ix
- lateral neck XR show soft tissue swelling
- CT from skull-base to diaphragm
Rx
- IV abx
- I+D (incision and drainage)
Strep Throat Complications
Lemierre’s Syndrome
IJV thrombophlebitis c¯ septic embolization most
commonly affecting the lungs.
Organism: Fusobacterium necrophorum
Rx
IV Abx: pen G, clinda, metro
Strep Throat Complications
Scarlet Fever
12-48h after pharyngotonsillitis
Sandpaper like rash on chest, axillae or behind ears
Circumoral pallor
Strawberry tongue
Rx
- Start pen V/G and notify HPA
Strep throat complications
Rheumatic Fever
Carditis Arthritis Subcutaneous nodules Erythema marginatum Sydenham’s chorea
Strep throat complications
Post-Streptococcal glomerulonephritis
Malaise + smoky urine 1-2 weeks after a pharyngitis
Larynx Function
Phonation
Positive thoracic pressure: inc. auto-PEEP
Respiration
Prevention of aspiration
Laryngitis
Usually viral and self-limiting
2O bacterial infection may develop
Symptoms: pain hoarseness and fever
o/e: redness and swelling of the vocal cords
Rx: Supportive, Pen V if necessary
Laryngeal Papilloma
Pedunculated vocal cord swellings caused by HPV
Present w hoarseness
Usually occur in children
Rx: laser removal
Recurrent Laryngeal Nerve Palsy
Supplies all intrinsic muscles of the larynx except for
cricothyroideus.
Ext. branch of sup laryngeal N.
Responsible for ab- and ad-uction of vocal folds
Recurrent Laryngeal Nerve Palsy Sx
Hoarseness
Breathy voice w bovine cough
Repeated coughing from aspiration (↓ supraglottic
sensation)
Exertional dyspnoea (narrow glottis)
Recurrent Laryngeal Nerve Causes
30% are cancers: larynx, thyroid, oesophagus,
hypopharynx, bronchus
25% iatrogenic: para- / thyroidectomy, carotid
endarterectomy
Other: aortic aneurysm, bulbar / pseudobulbar palsy
Laryngeal Squamous Cell Cancer
Assw alcohol, smoking
Presentation Male smoker Progressive hoarseness → stridor Dys-/odono-phagia Wt. loss
Ix - laryngoscopy + biopsy (inc nodes)
- MRI staging
Mx - based on stage
- radiotherapy
- laryngectomy
Laryngeal SCC
After total Laryngectomy
Pts have permanent tracheostomy
- speech valve
- electrolarynx
- oesophageal speech (swallowed air)
Regular follow up for recurrence
Laryngomalacia
Paeds airway issues
Immature and floppy aryepiglottic folds and glottis → laryngeal collapse on inspiration
Presentation
Stridor: commonest cause in children
Presents w/i first wks of life.
Noticeable @ certain times
Lying on back,
Feeding
Excited/upset
Problems can occur w concurrent laryngeal infections or w feeding.
Mx
Usually no Rx required but severe cases may warrant surgery
Epiglottitis
Paeds Airway Issues
Symptoms Sudden onset Continuous stridor Drooling Toxic
Pathogens: haemophilus, GAS
Rx
Don’t examine throat
Consult w anaesthetists and ENT surgeons
O2 + nebulised adrenaline
IV dexamethasone
Cefotaxime
Take to theatre to secure airway by intubation
Foreign Body
Paeds airway issues
Sudden onset stridor in a previously normal child.
Back slaps and abdominal thrusts.
Needle cricothyrotomy in children
Can only exclude foreign body in bronchus by
bronchoscopy
Subglottic Stenosis
paeds airway issues
Subglottis is narrowest part of respiratory tract in children.
Symptoms: stridor, FTT
Causes
Prolonged intubation
Congenital abnormalities
Rx
Mild: conservative
Severe: Tracheostomy or partial tracheal resection
Bell’s Palsy
path + features
Inflammatory oedema f CN7 in narrow facial canal
- probs viral origin (HSV1)
- 75% of facial nerve palsies
Features
Sudden onset: e.g. overnight
Complete, unilateral facial weakness in 24-72h
Failure of eye closure (Bell’s Sign) → dryness and conjunctivitis
Drooling, speech difficulty
Numbness or pain around ear
↓ taste (ageusia)
Hyperacusis: stapedius palsy
Bell’s Palsy Ix Mx
Ix
Serology: Borrelia or VZV Abs
MRI: SOL, stroke, MS
LP
Mx
- protect eyes (dark glasses, artificial tears, tape closed at night)
- give prednisolone w/i 72h >60mg PO for 5 days followed by tapering
- valciclovir if zoster suspected
- plastic surgery may helpif no recovery
Bell’s Palsy Prognosis
Incomplete paralysis usually recovers completely w/i wks.
With complete lesions:
80% full recovery
20% delayed recovery or permanent
neurological / cosmetic abnormalities.
Bell’s Palsy Complications
Synkinesis: e.g. blinking causes up-turning of mouth
Crocodile tears: eating stimulates unilateral lacrimation, not salivation
Ramsay Hunt Syndrome
path + Features
Reactivation of VZV in geniculate ganglion of CNVII
Features
- preceding ear pain or stiff neck
- vesicular rash in auditory canal (+/- TM, pinna, tongue, hard palate)
- no rash is zoster sine herpete
- ipsilateral facial weakness, aguesia, hyperacusis
- may affect CN7 > vertigo, tinnitus, deafness
Ramsay Hunt Syndrome
Mx - valaciclovir + prednisolone w/i 72h
Prognosis
- treated w/i 72h 75% recovery
- otherwise 1/3 recovery, 1/3 partial, 1/3 poor
Other facial palsy
not bell’s, ramsay hunt
Bilateral symptoms (Lyme, GBS, leukaemia,
sarcoid)
UMN signs: sparing of frontalis and orbicularis oculi
Other CN palsies (but seen in 8% of Bell’s)
Limb weakness
Rashes
Intracranial lesions and facial palsy
Vascular, MS, SOL (space occupying lesion)
Motor cortex → UMN signs
Brainstem nuclei → LMN signs
Cerebello-pontine angle lesion
May be accompanied by 5th, 6th, and 8th CN
palsies
Intratemporal/infratemporal lesions + facial palsy
Intratemporal lesions
Otitis media
Cholesteatoma
Ramsay Hunt
Infratemporal lesions
- parotid tumours
- trauma
Systemic facial nerve palsy
Peripheral neuropathy
Demyelinating: GBS
Axonal: DM, Lyme, HIV, Sarcoid
Pseudopalsy: MG, botulism