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BD Exam II Material (Richie) > E2L6 - Stress and Illness (Sigman) > Flashcards

E2L6 - Stress and Illness (Sigman) Flashcards

1
Q

I am an emotional, cognitive and/or behavioral response to stress. Who am I?

A

Coping

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2
Q

I am a real or imagined aversive or threatening event/situation. Who am I?

A

StressOR

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3
Q

I am a real (physical) or perceived (psychological) threat to the homeostasis of an organism, that produces an adaptive protective response. Who am I?

A

Stress

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4
Q

Homeostasis vs. Allostasis

A

Whereas homeostasis is a STATE of physiological equilibrium (between organism and environment), allostasis is the PROCESS of achieving homeostasis after a stressor.

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5
Q

Allogenic load

A

The burden the organism bears in the process of striving for homeostasis.

The allogenic load can be so great that it wears out the body.

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6
Q

What are the 2 types of stress?

A

Acute and chronic.

Note: Chronic stress is a human phenomenon; it involves psyche

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7
Q

What key analogy was used, to describe the relationship between

  1. Immediate effects
  2. Intermediate effects
  3. Prolonged effects

of stress?

A
  1. Text message
  2. Email
  3. Overnight delivery
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8
Q

The autonomic nervous system response, constitutes what kind stress response?

A

Immediate (eg. texting)

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9
Q

Unlike the autonomic response, which constitutes an immediate stress response:

  • Adrenal
  • Epi/NE
  • 20-30 seconds

…constitute what level of stress?

A

Intermediate effect (eg. email)

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10
Q

What is the most chronic and prolonged somatic response to stress?

A

The endocrine response. It’s the hardest to activate (req. greatest intensity of stimulation)

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11
Q

4 endocrine axes for stress include?

A
  1. Hypothalamic-pituitary-adrenal (HPAC)
  2. Somatotrophic axis
  3. Thyroid Axis
  4. Posterior Pituitary Axis
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12
Q

Which part of the brain, which is involved with long-term memory, directs neural impulses to the hypothalamus to release CRF?

A

Hippocampus

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13
Q

Summarize the HPA cascade

A
  1. Hippocampus stim. hypothal
  2. Hypothal secretes CRF to Ant. Pit.
  3. Ant. Pit releases ACTH
    (Endorphins are released too)
  4. ACTH stim. adrenal cortex
  5. Adrenal cortex releases CORTISOL

Bottom line: CORTISOL

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14
Q

What is the DAMPENER of the stress response?

A

Cortisol

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15
Q

What field explores the linkages between CNS, endocrine, and immune systems?

A

Psychoneuroimmunology

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16
Q

I am a regulatory protein, secreted by CNS and immune system. I can be pro-inflammatory, or anti-inflammatory. Who am I?

A

I’m a cytokine!

17
Q

Which of the following is FALSE about cortisol?
A. Inhibits lymphocyte prolif.
B. Inhibits pro-inflamm cytokines
C. Promotes shift from Th1 to Th2 cell activity
D. Promotes inflammation

A

D. Promotes inflammation

18
Q

Cards to be continued after psychological component of stress…

A

tbd…

BD Exam II Material (Richie) (7 decks)

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