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0
Q

Analysis of similarities and differences in development, provides insight that ontogeny recapitulates phylogeny

A

Comparative embryology

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1
Q

Accounts on the processes and sequential events of development, step by step account

A

Descriptive embryology

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2
Q

State the Recapitulation Theory

A

The development of an individual organism summarizes the development of its species. Ontogeny recaps phylogeny.

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3
Q

Von Baer’s law

A

General features appear earlier in development while specific features appear later.

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4
Q

Stage wherein different species appear almost identical

A

Phylotypic stage (stage 1)

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5
Q

Oviparous

A

Eggs develop outside mother

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6
Q

Viviparous

A

Embryo develops inside mother

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7
Q

Ovoviviparous

A

Eggs retained in mother’s body until birth

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8
Q

Causative factors in development, testing hypotheses by manipulating embryo

A

Experimental embryology

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9
Q

Pioneer of experimental embryology

A

Wilhelm Roux

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10
Q

Studies problems on conception and contraception

A

Reproductive biology

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11
Q

Emphasis of reproductive biology

A
Normal gametogenesis
Transport of gametes and fertilization
Reproductive endocrinology
Early embryonic development
Transplantation of mammalian embryo
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12
Q

Study of interaction chemical and physical events in development

A

Chemical embryology

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13
Q

Study of birth defects, malformations due to endogenous and exogenous factors

A

Teratology

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14
Q

Main stages in histological development

A

Proliferation, migration, differentiation

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15
Q

Genetic defects in teratology

A

Mutations, aneuploidy, translocation

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16
Q

Fetal alcohol syndrome

A

Malformations due to lack of cell proliferation

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17
Q

Phocomelia

A

Severely deficient or malformed limbs due to genetic inheritance, mutations, or thalidomide

Phoco - seal, melia- limb

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18
Q

Who cloned Dolly? Where?

A

Ian Wilmut and Keith Campbell at the Roslin Institute

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19
Q

The process of creating genetically identical animals

A

Animal cloning

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20
Q

Posed the question “how are different parts of a developing embryo formed?”

A

Aristotle

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21
Q

Defined preformation

A

Aristotle

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22
Q

What is preformation?

A

A miniature embryo is enclosed in the germ cell and requires only time and nourishment for it to develop.

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23
Q

What is epigenesis?

A

The gradual formation of new structures and organs. From a single cell arises a multicellular organism.

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24
Q

Spermists believe that…

A

Sperm cell contains an individual, ovum merely nourishes it

25
Q

A tiny human (____) in fetal position at head of sperm

A

Encasement concept, homunculus

26
Q

Ovists believe that…

A

Ovum contains the fetus, stimulated to grow by seminal fluid

27
Q

Who strengthened the ovist belief? How?

A

Charles Bonnet, upon discovering parthenogenesis in insects

28
Q

First to see human sperms with microscope

A

Anton van Leeuwenhoek and Louis Hamm

29
Q

Studied structure of relatively advanced fetuses

A

Galen

30
Q

Restrictions of Galen’s study

A

Prevented serious analysis of early embryonic development due to miniature dimensions of embryo

31
Q

Founder of modern reproductive biology

A

Reignier de Graaf

32
Q

Described ovarian follicles and fallopian tubes, studied ectopic pregnancy

A

Reigniet de Graaf

33
Q

Lazzaro Spallanzani believed that

A

Male and female sex products are necessary to initiate development

34
Q

What did Marcello Malphigi do?

A

Described accurately the development of chick in egg.

35
Q

Developed modern comparative embryology

A

Karl Ernst von Baer

36
Q

Germ Layer theory was proposed by:

A

Karl Ernst von Baer

37
Q

State the Germ Layer Theory

A

There exists three germ layers from which organs are derived.

38
Q

“Embryo development occurs through progressive remodeling and growth.”

A

Caspar Friedrich Wolff

39
Q

Developed the cell theory

A

Matthias Schleiden, Theodor Schwann, and Rudolf Virchow

40
Q

Implications of the Cell Theory

A

Embryology became a bona fide science, proved that development must occur via epigenesis

41
Q

Theorized that development must follow a mosaic pattern

A

August Weismann

42
Q

State the Germ Plasm Theory. Who proposed it?

A

Differentiated the somatic and germ cells, August Weismann

43
Q

Function of somatic cells according to Germ Plasm Theory.

A

For the protection and proliferation of the germ plasm.

44
Q

Function of germ cells according to Germ Plasm Theory.

A

For perpetuation of the species.

45
Q

Other name for Mosaic Development

A

Weismann’s Theory of Nuclear Determination

46
Q

Why is the Mosaic Model called as such?

A

Egg is considered a mosaic of discrete localized determinants.

47
Q

Describe Mosaic development.

A

Nuclei contain factors that ate asymmetrically distributed in daughter cells, fate of each cell is predetermined.

48
Q

What experiment did Roux perform?

A

Ablation Experiment or Embryonic Extirpation

49
Q

Removed large pieces from eggs and discovered that any single monad was capable of forming any part of the completed embryo.

A

Hans Adolf Eduard Driesch

50
Q

Consequence of Driesch’s experiment.

A

Led to the terms pluripotent and totipotent.

51
Q

Describe regulative development.

A

Ability of the embryo to develop even if some cells are removed or rearranged.

52
Q

Who performed the Induction and Transplantation experiments?

A

Hans Spemann and Hilde Mangold.

53
Q

What is the organizer/evocator?

A

Dorsal lip of blastopore.

54
Q

Distinguished between phenotype and genotype.

A

Wilhelm Johanssen

55
Q

Describe the relationship between genotype and phenotype.

A

Genes are manifested through phenotype only upon the activation depending on time and space.

56
Q

Worked on mutant genes and discovered genes encoded proteins.

A

Salome Glueksohn-Waelsch and Conrad Waddington

57
Q

Unified science of embryology and genetics.

A

Developmental Genetics

58
Q

Coined epigenetics.

A

Conrad Waddington

59
Q

Epigenetics states that

A

The development of an embryo is due to a series of causal interactions between parts. It accounts for the development of an embryo and reminds one that genetic factors are the most important determinants of development.