E1 Review Flashcards

1
Q

Which class of antibody reacts best at room temperature?

a) IgG
b) IgM
c)IgE
d) IgA

A

IgM

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2
Q

IgG antibodies are clinically significant for HDN because

a) They are too big to escape the vein
b) They fix compliment
c) They demonstrate dosage
d) They are small enough to cross the placenta

A

They are small enough to cross the placenta

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3
Q

Hemolysis is positive reaction that indicates you have most likely identified antibodies that -

a) react at AHG
b) Fix complement
c) Cross the placenta
d) Are immune stimulated

A

Fix compliment

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4
Q

Which of the following is known as the membrane attack complex in the classical pathway?

a) C1
b) C3
c) C4, C2, C3
d) C5bC6C7C8C9

A

C5bC6C7C8C9

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5
Q

True or False: Most Antigens we have discussed are inherited autosomal dominant.

A

True

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6
Q

A father is Xga+ and his wife is Xga- what will the phenotypes of offspring be?

a) His daughters will be Xga+ and Sons will be Xga-
b) His daughters will be Xga- and his sons will be Xga+
c) All of the children will be Xga-
d) All of the children will be Xga+

A

check review

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7
Q

As RBCs are stored which of the following increases?

-Plasma potassium
- 2, 3 DPG
- ATP
- pH

A

Plasma potassium

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8
Q

What is the longest length of time that the FDA says red cells can be stored for ?

a) 51 days
b) 42 days
c) 35 days
d) 28 days

A

b) 42 days

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9
Q

When there is a shift to the left, hemoglobin affinity for oxygen does what?

a) increases
b) decreases

A

increases

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10
Q

What is the maximum time a sample may be obtained before a transfusion for pre transfusion testing?

a) 24 hours
b) 8 hours
c) 3 days
d) 7 days

A

c) 3 days

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11
Q

The immunodominant sugar responsible for group B specificity is…

a) N-acetyl galactosamine
b) D-Galactose
c) Fucose
d) N-acetyl glucosamine

A

D-Galactose

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12
Q

What is the most common cause of the following results?

Anti-A: 3+ mf
Anti-B: 4+
A1 cell: 0
B cell: 0

a) Bacterial infection
b) Transfusion
c) Hemolytic disease of the newborn
d) Immunocompromisedd

A

b) transfusion


mixed fixed is usually seen with transfusion

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13
Q

Acquired B antigens are found in which individuals?

a) Bombay individuals
b) Group O persons
c) All blood groups
d) Group A persons

A

d) Group A persons

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14
Q

Which blood type should NOT results form the union of an AB male to an O female?

a) A
b) B
c) O
d) none of these

A

c) O

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15
Q

A child is blood typed as A, their mother is blood type B, what blood type must the father be?

a) A
b) B
c) O
d) Bombay

A

A

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16
Q

Which of the following statements is true?

a) an individual with AO genotype is homozygous for A
b) An individual with BB genotype is homozygous for B
c) An individual with OO genotype is heterozygous for O
d) An individual with AB genotype is homozygous for A and B

A

b) An individual with BB genotype is homozygous for B