Dystocia Flashcards

1
Q

What is the most common cause of dystocia in cattle and sheep?

A

cattle - feto-maternal disproportion
sheep - malpresentations

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2
Q

What are the effects of dystocia?

A
  • Reduced welfare
  • Reduced production
    • Cow = subsequent lactation
    • Calf = 1st lactation
  • Stillbirth
  • Dam death
  • Postpartum problems
    • E.g. RFM, metritis, injuries
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3
Q

What are the options for management of dystocia?

A
  • Manual correction and deliver per vaginum
  • Caesarean section
  • Foetotomy (foetus needs to be dead)
  • Euthanasia of dam +/- foetus
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4
Q

When is manual correction and delivery successful?

A

If foeto-maternal disproportion NOT present
- Malpresentations
- Some soft tissue obstructions (e.g. vulval stenosis)

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5
Q

What are the indications for a caesarean section? When is it not suitable?

A
  • foeto-maternal disproportion
  • malpresentations that cannot be corrected
  • breech calves
  • elective (e.g. high value calves)

Not suitable if calf decomposing -> foetotomy
- Alternative approach needed if C-sec performed

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6
Q

What are the advantages and disadvantages of a C sec?

A

Advantages
* Increased chances of live birth
* Reduced risk of secondary complications such as nerve injury
* Can be quicker and less injurious to dam than prolonged difficult calving/lambing/kidding
* Survival rates for dam and offspring are favourable
* Can be quicker than a difficult per vaginum delivery
* The only method to deliver an oversized foetus intact

Disadvantages
* Inherent surgical and anaesthetic risks apply (as to all surgeries)
* But… may be increased risk of secondary infection (e.g. peritonitis) or adhesions
* Requires veterinary qualification and surgical competency
* Can be physically demanding in cattle, especially if the calf is large

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7
Q

What are the indications for foetotomy? What is the difference between partial and total foetotomies?

A

Indications Foetus is already dead
* Foeto-maternal disproportion
* Pathological foetal oversize
* Congenital foetal malformations
* Malpresentations that cannot be corrected

Partial = removal of part of the foetus only (e.g. head)
Total = division of the whole foetus into two or more sections

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8
Q

What are the advantages and disadvantages of foetotomies?

A

Advantages
* Reduction in foetal size allows easier delivery
* Can be quick (especially partial)
* Can be done without assistance (although assistance recommended if possible)
* Avoids C-sec
* Especially useful if C-sec contraindicated (emphysematous foetus)
* Better for dam in some circumstances
* Can be performed with minimal equipment if required
* Especially sheep
* Partial needs less equipment

Disadvantages
* Risk of iatrogenic injury
* Can be severe or even life-threatening
* Can take a long time (especially total)
* Exhaustion of dam and vet
* Requires training and technical competency

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9
Q

What are dropsical conditions? What are the 2 types?

A

‘Dropsy’ = accumulation of fluid

Hydrallantois
* Excess fluid accumulation in the allantois
* 85-90% of bovine cases
* Placental origin
* Foetus normal
* Sporadic occurrence
* Up to 10x expected volume of allantoic fluid
* Normal = 8-15 L
* Fluid accumulates after mid-gestation
* Failure in mechanisms of production and absorption
* Reduced number of placentomes
* Permanent alteration of endometrium
* Prognosis guarded to poor
* If survives, cull of cow recommended

Hydramnion
* Excess fluid accumulation in the amnion
* ~10% of bovine cases
* Foetal origin
* Foetal abnormalities present
* Related to foetal abnormalities
* Failure of swallowing or digestion of foetal fluids
* Future breeding prognosis of dam is reasonable
* Progressive abdominal enlargement in 3rd trimester
* Slower development than hydrallantois
* Uterus and abdomen accommodates extra fluid better
* Less sick cow
* Placentomes still palpable
* May go undiagnosed until parturition
* Large volume of thick, syrupy fluid
* Foetal abnormalities

Occasionally both occur together

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10
Q

What clinical signs are associated with hydroallantois?

A
  • Bilateral abdominal distention
    • Symmetrical
  • Uncomfortable
  • Inappetant
  • Reduced/absent rumen function
    • Due to compression
  • Recumbency
  • Tight uterine wall palpable per rectum
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11
Q

How would you treat hydroamnion/hydroallantois?

A

Induce/terminate pregnancy
* Prostaglandin / steroids
* Need to provide replacement fluids to cow
* Prevent hypovolaemia
* Correct electrolyte disturbances

Euthanasia
- Salvage slaughter if fit to travel

Trochar and drain fluid
* Rapidly re-accumulation of fluid occurs in hydrallantois
* Need to provide replacement fluids to cow

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12
Q

What is arthrogryposis? What are causes?

A
  • Relatively common malformation
  • Limb ankylosis
    • Usually combined with other congenital malformations (e.g. cleft palate)
  • Liveborn neonates unable to stand -> euthanasia
  • Foetotomy or C-sec usually needed

Causes
* Genetic
* Autosomasal recessive in Charolais breed
* Viral infection in utero
* Schmallenberg virus
* Bluetongue virus
* Akabane virus
* Teratogenic plants
* Lupines (not all species)

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13
Q

What is schistosomus reflexus?

A
  • Inside out’ foetuses
  • Rare, fatal malformation
    • Likely genetic
  • Foetotomy or C-sec
  • Be careful not to confuse with uterine rupture
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14
Q

What is congenital chondrodysplasia?

A
  • ‘Bulldog’ calves
    • Short legs
    • Domed head
    • Brachygnathia inferior (undershot jaw)
  • Dexters, Holstein, Jerseys
    • Likely genetic
    • Other breeds reported
  • Does not always = dystocia
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15
Q

What is hydrocephalus?

A
  • Increase in CSF volume -> domed head
  • Calves born alive may have neuro deficits
  • Teratogenic viruses implicated
    • BVDv
    • BTV
    • Akabane virus (not UK)
  • May also form part of mixed congenital disorders
  • Mild cases may calve unassisted
  • Severe cases = C-sec
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16
Q

What is large offspring syndrome?

A
  • Also termed ‘abnormal offspring syndrome’
    • Varied congenital abnormalities reported
  • Associated with assisted reproductive technologies
    • Embryo transfer
    • In vitro techniques
    • Cloning
  • Exact mechanisms unclear
  • Very large neonates
    • May be 2x average size
    • Dystocia
    • Macroglossia (enlarged tongue)
17
Q

What are possible cranial defects?

A
  • Ancephaly – no head (images 1a and 1b)
  • Otocephaly – some head structures present but no skull (image 2)
  • Bicephaly – two heads (image 3)
18
Q

What are teratogens? How does the timing of exposure affect the influence they have?

A

Teratogen = agents causing foetal abnormalities or death
Zygote = affected by chromosomal or genetic abnormalities. Often result in embryonic death
Embryo = affected by environmental and infectious agents. Most high risk period for developing abnormalities
Foetus = more resistant to environmental teratogens but structures that develop late are still susceptible to being affected (e.g. palate)

19
Q

What are common environmental teratogens? What effect do they have?

A

Hemlock
* Skeletal abnormalities if ingested between days 40-70 of gestation
* Abortion
* NB. is highly toxic to cattle and often causes death of dam

Nitrates/nitrites - Nitrate accumulating plants e.g. sugar beet, alfalfa or Nitrite based fertilisers
* Excess nitrate consumption exceeds rumen capacity for metabolism -> nitrate and nitrite absorbed into circulation -> interacts with haemoglobin -> oxidation to methaemoglobin
* This process can also occur in the placenta -> foetal death, weak calves

Ergotism - Mouldy feed
* Reduced size offspring

Lead
* Concentrates in CNS of foetus
* Neurological defects
* Reduced foetal size

20
Q

What are examples of pharmacological teratogens? What effect do they have?

A

Benzimidazoles
* Sheep
* Abnormalities of the foetal skeleton, kidneys and vascular system

Tetracyclines
* All ruminants
* Dental discolouration

Steroids
* All ruminants
* Abortifacient

Prostaglandins
* All ruminants
* Abortifacient

Xylazine
* All ruminants
* Abortifacient in later stages of pregnancy

21
Q

Why is early pregnancy in heifers not ideal?

A
  • Remember puberty in cattle driven by weight, not age
    • Puberty occurs at ~2/3 of adult bodyweight
  • Well-grown heifers can therefore unexpectedly conceive to mis-mating
    • Uncastrated youngstock
    • Bulls running with herd
    • Entire males escaping
  • Poor heifer growth
    • Increased risk of dystocia
22
Q

What are the management options for early pregnancy?

A

Wait and see
* C-sec likely needed -> can be less optimal outcomes if performed in emergency
* Can be effective if farmer aware of mis-mating and requests vet assistance as soon as parturition starts
* Only addresses issue of dystocia

Elective caesarean
* Performed at/near end of gestation before parturition starts
* Need a idea of gestation duration à scan
* Only addresses dystocia

Induce parturition
* Aim to induce near/at term for viable but small foetus
* May still need C-sec if calf big
* Requires reliable insemination date -> scan
* Only addresses dystocia

Terminate pregnancy
* Prostaglandin
* Glucocorticoid steroids (dexamethasone)
* Reliability dependent on stage in gestation -> scan
* Early termination can mean limited effects of pregnancy on dam

23
Q

Why is prostaglandin used in pregnancy termination? When is it best to use it?

A
  • Lysis of CL -> pregnancy loss
    • Progesterone needed to maintain pregnancy
  • Stage of gestation is important factor in successful treatment
    • < 100 days gestation = maximal chances (> 90%)
    • 101-150 days gestation = moderate chances (~ 60%)
    • > 150 days gestation = lower chances (≤ 40%)
      • Because placenta also a source of progesterone between days 150-200
    • > 270 days gestation to induce parturition -> live calf
  • Abortion occurs within 7days if given < 100 days gestation
    • > 100 days gestation timing and reliability of abortion reduced
24
Q

Why are glucocorticoid steroids used in pregnancy termination?

A
  • Reduces placental secretion of progesterone -> pregnancy loss
    • Most effective in last month of gestation
    • Can also be used after day 270 to induce parturition -> live calf

Dexamethasone
Give 20-30mg (for most products this is 10-15ml)

25
Q

When would you give both prostaglandin and dexamethasone?

A
  • For mid to late gestation (i.e. > 150 days) or if uncertain give both dexamethasone and prostaglandin
    • Reduces progesterone from both placental and CL sources
    • Increases likelihood of success
  • Both drugs associated with increased likelihood of retained foetal membranes (covered this afternoon)
  • No other adverse effects for the heifers reported