Dyspnea and Cough (Tyler) Flashcards
What is the etiology of Churg-Strauss?
Idiopathic
What lab is important for dx GPA/WG?
c-ANCA
What might you include in the ddx for an acute cough?
URI or post-viral cough Pneumonia Pulmonary edema PE Aspiration pneumonia
What is the hallmark CXR finding in sarcoidosis?
Hilar adenopathy
Who usually presents with idiopathic pulmonary fibrosis?
Men in their 6th and 7th decades, current and past smokers
What diagnostic triad do we see in GPA (WG)?
URI, LRI, glomerulonephritis
What is the hallmark feature of idiopathic pulmonary fibrosis?
Heterogenous distribution of parenchymal fibrosis against background of mild inflammation (UIP)
What is idiopathic pulmonary fibrosis clinically characterized by?
Progressive parenchymal scarring and loss of pulmonary function
What extra pulmonary manifestations do we see with idiopathic pulmonary fibrosis?
Clubbing and right heart failure
What do we see in an CXR with idiopathic pulmonary fibrosis?
Bilateral reticular opacities
What might you include in the ddx for dyspnea?
Pneumonia COPD Asthma Pneumothorax Pulmonary emboli Cardiac disease (i.e. HF, AMI, valvular dysfunction) Difffuse alveolar hemorrhage Metabolic acidosis Cyanide toxicity Interstitial lung disease
Are the granulomas in GPA/WG caseating?
Yes
What might you include in the ddx for a non-pulmonary cough?
GERD Postnasal drip Sinusitis HF Laryngitis
Who does GPA/WG usually present in?
30-50YO
What is the gold standard for idiopathic pulmonary fibrosis dx?
Lung biopsy
What are the three most common causes of dyspnea?
Heart disease
Lung disease
Anemia
What might you include in the ddx for a chronic cough?
Post-nasal drip*
Asthma*
GERD*
Pulmonary infection*
Bronchiectasis, bronchitis, TB, CF, MAC, asthma, COPD, ACEi, environmental exposures, sarcoidosis, b-blockers
What is the only tx shown to prolong survival in idiopathic pulmonary fibrosis?
Lung transplant
What is the etiology of sarcoidosis?
Unknown
Which vasculitides do we see sx of asthma and marked peripheral eosinophilia?
Churg-Strauss
Are the granulomas in sarcoidosis caseating?
No
Which vasculitides affects multiple organ systems, most common the skin and lungs?
Chung Strauss
What is the most prominent sx seen in idiopathic pulmonary fibrosis?
Progressive dyspnea
