Dysmenorrhea Flashcards
Endometriosis, adenomyosis, PID
Dysmenorrhea
Painful menstruation
2 types of dysmenorrhea
- Primary
- Secondary
Primary dysmenorrhea
Painful menstruation usually appearing in 1 year of menarche
Primary dysmenorrhea occurs with
ovulatory cycles
When does pain occur in primary dysmenorrhea
begins with onset of menstruation
Type of pain in primary dysmenorrhea
spasmodic- type
Cause of primary dysmenorrhea
Due to physiological release of Prostaglandin 2 (PGE2) which cause contraction and cause pain
Mx of primary dysmenorrhea
usually self- limiting
* NSAIDs
* COCP- combined Oral Contraceptives
Main component responsible for primary dysmenorrhea
Prostaglandin 2 (PGE 2)
Secondary dysmenorrhea onset
3rd - 4th decade of life
Secondary dysmenorrhea- type of pain
Congestive pain
Associated Sx of Secondary dysmenorrhea
- Pelvic heaviness
- Back pain
Secondary dysmenorrhea is associated with
- Cycle irregularity
- Heavy periods
- Dyspareunia
- Vaginal discharge
- IMB
- Post- coital bleeding and pain
Causes of Secondary dysmenorrhea
- Endometriosis
- Adenomyosis
- Intra- uterine polyps
- Submucosal fibroids
- IUCD
- PID
- Congestive uterine abnormalities
- Cervical stenosis
- Ashermann Syndrome
- Uterine retroversion
Endometriosis
Epidemiology
8%- 10% of women in reproductive years
Endometriosis
Endometriosis
Presence of functioning endometrial tissue ( glands and stroma) at** sites outside the uterine cavity** which induces a chronic inflammatory reaction
Endometriosis
Theories about the pathophysiology
- Retrograde menstruation
- Hematological or lymphatic spread
- Celomic hyperplasia
T/F
- MCC of dysmenorrhea is PID
- Cause of endometriosis is unknown
- Secondary dysmenorrhea pain is spasmodic
- Dysmenorrhea is due to the release of PGE2
- Secondary dysmenorrhea is seen from 2nd to 4th decade of life
- F ( endometriosis)
- T
- F ( congestive- type)
- F (only primary )
- F (3-4th decades)
Endometriosis
Sites
- Uterosacral ligament
- Ovaries
- Fallopian tube
- Rectovaginal septum
- Outer surface of uterus
- lining of the pelvic cavity
- Bladder
- Bowel
- Vagina
- Cervix
- Vulva
- Abdominal surgical scars
- Less common- arm, lung, thigh
Endometriosis
Risk factors
- Age
- Increased peripheral body fat
- Greater exposure to menstruation
- Genetic predisposition
Endometriosis
Why is greater exposure to menstruation a risk factor
due to short cycles, Long duration of flow, reduced parity
Endometriosis
Sx
- Dysmenorrhea >6 months
- Chronic pelvic pain
- Deep dyspareunia
- Dyschezia
- Pain on micturition
- Pain on exercise
- Subfertility
- Non specific Sx- Fatigue, General malaise, sleep disturbances
- Cyclical rectal bleeding (hematochezia)
- Hematuria
Endometriosis
Dysmenorrhea should be present for
> 6 months
Endometriosis
- Most patients are asymptomatic
- Endomteriosis can be seen in vulva
- Celomic hypoplasia is a pathophysiological theory behind endometriosis
- T
- T
- F ( hyperplasia)
Endometriosis
Ix
- Laparoscopy
- CA 125
- TVUSS
- MRI
Endometriosis
Gold standard Dx test
Laparoscopy
Endometriosis
Why is laparoscopy the gold standard test
for direct visualization and confirmation by biopsy when there is a doubt
Endometriosis
Why is laparoscopy done
to exclude malignancy- malignant transformation of endometrioma
Endometriosis
Endometrioma
a malignant tumor with chocolate coloured blood
Endometriosis
Is endometrioma common
Rare 0.7%
Endometriosis
CA125 uses
No evidence to say it is useful as a screening test but levels will be high in severe disease
Endometriosis
CA 125 levels in severe endometriosis
raised
Endometriosis
TVUSS uses
to detect ovarian endometrioma