Cervical CA

Question 1

Cervical CA

Colour of ectocervix

Answer 1

Pink

Question 2

Cervical CA

Colour of endocervix

Answer 2

Red

Question 3

Cervical CA

Epithelium of ectocervix

Answer 3

squamous epthelium

Question 4

Cervical CA

Epithelium of endocervix

Answer 4

columnar epithelium

Question 5

Cervical CA

SCJ

Answer 5

junction between the ectocervix and endocervix

Question 6

Cervical CA

T zone

Answer 6

area between the new SCJ after puberty and the old SCJ before puberty

Question 7

Cervical CA

What happens to the SCJ after menopause

Answer 7

goes into the endocervical canal and the SCJ relocates.

Question 8

Cervical CA

Cervical CA is the…….. most common cancer among females in SL

Answer 8

third most common

Question 9

Cervical CA

MCC of Cervical CA

Answer 9

Recurrent HPV infections

Question 10

Cervical CA

Low risk serotypes of HPV

Answer 10

6, 11

Question 11

Cervical CA

Low risk HPV cause

Answer 11

genital warts

Question 12

Cervical CA

High risk HPV serotypes

Answer 12

16, 18, 31, 33, 45

Question 13

Cervical CA

High risk subtypes of HPV cause

Answer 13

cervical CA

Question 14

Cervical CA

HPV is a DNA/ RNA virus

Answer 14

dsDNA

Question 15

Cervical CA

Site of HPV infection

Answer 15

TZ

Question 16

Cervical CA

HPV integrates into the ……….. epithelium of the cervix

Answer 16

basal cells

Question 17

Cervical CA

CIN

Answer 17

pre- malignant lesion of cervical CA

Question 18

Cervical CA

High risk women to get cervical CA

Answer 18

smoking, immunocompromised

Question 19

Cervical CA

Nabothian follicle

Answer 19

When squamous epthelium grows on the columnar epithelium, mucus retention forms a follicle

Question 20

Cervical CA

Roughly how long does it take for the CA to develop after an infection

Answer 20

~ >20 - 30 years

Question 21

Cervical CA

LSIL includes

Answer 21

• HPV infected koilocytes stage
• CIN 1

Question 22

Cervical CA

HSIL includes

Answer 22

• CIN 2
• CIN 3

Question 23

Cervical CA

Regression is more common in

Answer 23

LSIL stage and in women < 30 years

Question 24

Cervical CA

HSIL has a high chance of progression/ regression

Answer 24

progression

Question 25

Cervical CA

CIN 1

Answer 25

• lower 1/3 affected
• very mild/ dysplasia

Question 26

Cervical CA

CIN 2

Answer 26

• lower + middle 1/3
• moderate dysplasia

Question 27

Cervical CA

CIN 3

Answer 27

• full cervix affected
• severe dysplasia and CA in- situ

Question 28

Cervical CA

Screening for CIN

Answer 28

• visual inspection w acetic acid (VIA)
• visual inspection w Lugol’s iodine ( VILI)
• conventional cytology / pap smear
• Liquid based cytology
• HPV/ DNA test

Question 29

Cervical CA

VIA

Answer 29

• 5% acetic acid
• acetowhite area due to abnormal protein

Question 30

Cervical CA

VILI

Answer 30

abnormal area stains less brown/ almost whitish

Question 31

Cervical CA

Papanicolaou instruments

Answer 31

• Cusco’s speculum
• Ayer’s spetula
• cytobrush
• Slides
• Alcohol jar

Question 32

Cervical CA

Cusco’s speculum

Answer 32

• bivalve self- retaining vaginal speculum
• one valve on the anterior wall of vagina
• other on the posterior wall

Question 33

Cervical CA

Ayers’ spatula

Answer 33

• wooden spatula
• rotate and scrape the ectocervix

Question 34

Cervical CA

Cytobrush is used to

Answer 34

scrape the SCJ

Question 35

Cervical CA