Dyslipidemias Flashcards
1
Q
Presentation: - Steatorrhea, ataxia, night blindness - Enterocytes swollen with TGs - Acanthocytosis of RBCs Treatment: - Vitamin E
A
Abetalipoproteinemia
2
Q
AR
- Lipoprotein lipase deficiency or defective ApoC-2
- Increased chylomicrons, TG’s, cholesterol
- Presentation: pancreatitis, hepatosplenomegaly, pruritic xanthomas
- No increased risk for atherosclerosis
A
Type 1 hyperchylomicronemia
3
Q
AD
- Absent or decreased LDL receptors
- Presentation: tendinous xanthomas, corneal arcus, accelerated atherosclerosis, MI (young!)
A
Type 2a familial hypercholesterolemia
4
Q
AD
- Overproduction of VLDL
- Presentation: pancreatitis
A
Type 4 hypertriglyceridemia
5
Q
AR
- Defective Apo-E
- Premature atherosclerosis, tuberoeruptive xanthomas, xanthoma striatum palmare
A
Type 3, dysbetalipoproteinemia
