Autoantibodies Flashcards

1
Q

Rheumatoid Arthritis?

A
  • Anti-IgG ab

- Anti-citrullinated protein ab

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2
Q

Lupus (SLE)?

A
  • Anti-nuclear ab
  • Anti-dsDNA
  • Anti-Smith
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3
Q

Drug induced lupus?

A

-Anti-histone ab

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4
Q

CREST scleroderma?

A

-Anti-centromere ab

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5
Q

Diffuse scleroderma?

A

Anti-Scl-70 (Anti-DNA topoisomerase 1)

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6
Q

Polymyositis/Dermatomyositis?

A
  • Anti-nuclear ab
  • Anti-Jo-1 (anti-histidyl-tRNA synthetase)
  • Anti-SRP
  • anti-Mi-2 ab
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7
Q

Sjogren?

A
  • Anti-SSA (Ro)

- Anti-SSB (La)

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8
Q

Mixed CT Disease?

A

Anti-U1-RNP

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9
Q

Pemphigus Vulgaris?

A

Anti-desmoglein

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10
Q

Myasthenia Gravis?

A

Anti-ACh receptor

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11
Q

Celiac Disease?

A
  • Anti-endomysial (anti-tissue transglutaminase)

- Anti-gliadin

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12
Q

Primary Biliary Cholangitis?

A

Anti-mitochondrial ab

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13
Q

Autoimmune Hepatitis?

A

Anti-smooth muscle

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14
Q

Type 1 DM?

A

Anti-glutamate decarboxylase

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15
Q

Graves disease?

A
  • Anti-thyrotropin receptor

- Anti-thyroglobulin

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16
Q

Hashimoto Thyroiditis?

A
  • Anti-thyroid peroxidase (anti-TPO)

- Anti-thyroglobulin

17
Q

Goodpasture Syndrome?

A

Anti-basement membrane

18
Q

Granulomatosis with Polyangitis?

A

c-ANCA

19
Q

Microscopic Polyangiitis
Pauci immune Crescentic GN
Churg Strauss Syndrome
ULCERATIVE COLITIS

A

p-ANCA

20
Q

Antiphospholipid syndrome?

A
  • Anticardiolipin
  • lupus anticoagulant
  • anti-beta2glycoprotein ab
  • low complement levels
21
Q

Crohn’s Disease?

A

anti-saccharomyces cervisiae ab (ASCA)