Autoantibodies

Question 1

Rheumatoid Arthritis?

Answer 1

• Anti-IgG ab

- Anti-citrullinated protein ab

Question 2

Lupus (SLE)?

Answer 2

• Anti-nuclear ab
• Anti-dsDNA
• Anti-Smith

Question 3

Drug induced lupus?

Answer 3

-Anti-histone ab

Question 4

CREST scleroderma?

Answer 4

-Anti-centromere ab

Question 5

Diffuse scleroderma?

Answer 5

Anti-Scl-70 (Anti-DNA topoisomerase 1)

Question 6

Polymyositis/Dermatomyositis?

Answer 6

• Anti-nuclear ab
• Anti-Jo-1 (anti-histidyl-tRNA synthetase)
• Anti-SRP
• anti-Mi-2 ab

Question 7

Sjogren?

Answer 7

• Anti-SSA (Ro)

- Anti-SSB (La)

Question 8

Mixed CT Disease?

Answer 8

Anti-U1-RNP

Question 9

Pemphigus Vulgaris?

Answer 9

Anti-desmoglein

Question 10

Myasthenia Gravis?

Answer 10

Anti-ACh receptor

Question 11

Celiac Disease?

Answer 11

• Anti-endomysial (anti-tissue transglutaminase)

- Anti-gliadin

Question 12

Primary Biliary Cholangitis?

Answer 12

Anti-mitochondrial ab

Question 13

Autoimmune Hepatitis?

Answer 13

Anti-smooth muscle

Question 14

Type 1 DM?

Answer 14

Anti-glutamate decarboxylase

Question 15

Graves disease?

Answer 15

• Anti-thyrotropin receptor

- Anti-thyroglobulin

Question 16

Hashimoto Thyroiditis?

Answer 16

• Anti-thyroid peroxidase (anti-TPO)

- Anti-thyroglobulin

Question 17

Goodpasture Syndrome?

Answer 17

Anti-basement membrane

Question 18

Granulomatosis with Polyangitis?

Answer 18

c-ANCA

Question 19

Microscopic Polyangiitis
Pauci immune Crescentic GN
Churg Strauss Syndrome
ULCERATIVE COLITIS

Answer 19

p-ANCA

Question 20

Antiphospholipid syndrome?

Answer 20

• Anticardiolipin
• lupus anticoagulant
• anti-beta2glycoprotein ab
• low complement levels

Question 21

Crohn’s Disease?

Answer 21

anti-saccharomyces cervisiae ab (ASCA)