Dyslipidemia Flashcards
5 major types of lipoproteins
chylomicrons, VLDL, LDL, HDL, and IDL
NCEP guideline for screening for high blood cholesterol
aged 20 or older
lipid profile test. fast for previous…
9-12 hours
USPSTF Screening recommendation for high blood cholesterol
begin at age 20 if increased risk of CHD. Men without increased risk begin screening at age 35. repeat every 5 years if low or average risk
clinical manifestation if very high chylomicrons and VLDL levels
eruptive xanthomas
clinical manifestation if very high levels of LDL
tendinous xanthomas- often on achilles or back of hand
clinical manifestation if very high levels of triglycerides
lipemia retinalis
what enzymes should be monitored when giving statins for dyslipidemia?
liver and muscle enzymes. because statins may cause severe, but uncommon SE including myositis, rhabdomyolysis, liver failure
Niacin SE
flushing. take ASA 30 min before to avoid
what would you warn patients of when putting them on gemfibrozil
SE= cholelithiasis, hepatitis, myositis
Best med for decreaseing triglycerides
gemfibrozil, niacin, omega 3 acids, statsin
inherited lipid disorders
familial hypercholesterolemia, familial hyperchylomicronemia
chylomicrons
liporprotein that carries dietary lipid
IDL
lipoprotein that carries cholesterol esters and triglycerides
VLDL
lipoprotein that carries endogenous triglycerides and cholesterol
