Diabetic Complications Flashcards

1
Q

If episode of hypoglycemia occurs in diabetic patient,

A

ingest 15 gm carbohydrate and recheck glucose levels in 15 minutes

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2
Q

most common cause of hypoglycemia in non diabetic patients

A

drugs

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3
Q

whipple’s triad

A
  1. sx of hypoglycemia present. 2. plasma glucose conc low when sx are present. 3. sx relieved by administration of glucose
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4
Q

tx for non diabetic hypoglycemia

A

dietary therapy, glucose therapy

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5
Q

Lab findings for DKA

A

increased glucose, BUN, creatinine, phosphate, potassium, WBC, plasma osmolality, amylase, lipase, lipids. Decreased sodium and bicarbonate, pCO2. Increased anion gap. Ketonuria and serum ketones

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6
Q

Higher mortality rates in DKA or HHS

A

HHS (hyperosmolar hyperglycemic state)

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7
Q

Lab findings in HHS

A

very high levels of glucose, BUN/creatinine, and plasma osmolality. potassium levels often normal

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8
Q

Tx of DKA and HHS

A

Fluid, insulin, and electrolyte management

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9
Q

target glucose levels in DKA and HHS

A

For DKA, less than 200 mg/dL. And for HHS, 250-300 mg/dL

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10
Q

Patient with DKA. Give fluid and insulin. Know their blood glucose is 180 mg/dL. Next step?

A

Change IVF to dextrose containing solution. IV insulin continued until serum anion gap is below 12 meq/L, serum bicarbonate above or equal to 18 meq/L, and venous pH is above 7.3

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11
Q

electrolyte management in DKA and HHS

A

potassium replacement when levels less than 5.3 meq/L. phosphate replacement when levels less than 1 mg/dL

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12
Q

complications of DKA and HHS

A

electrolyte abnormalities, cerebral edema, and non cardiogenic pulmonary edema

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13
Q

Most common complication of diabetes mellitus

A

diabetic neuropathy

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14
Q

most common peripheral mononeuropathy

A

medial nerve palsy

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15
Q

Mononeuropathy multiplex

A

multiple mononeuropathies in same patient. results in asymmetric polyneuropathy

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16
Q

diabetic neuropathy categories

A

distal symmetric polyneuropathy, autonomic neuropathy, monoradiculopathy (cranial and peripheral mononeuropathy)
, mononeuropathy multiplex, polyradiculopathy

17
Q

most common polyradiculopathy

A

diabetic amyotrophy

18
Q

types of polyradiculopathy

A

diabetic amyotrophy, thoracic polyradiculopathy, and diabetic neuropathic cachexia

19
Q

what neuropathy would you be worried about in diabetic with severe weight loss and depression

A

diabetic neuroapthic cachexia

20
Q

diabetic neuropathic cachexia prognosis

A

spontaneous improvemnt in 1-2 years. no tx.

21
Q

retinopathy peak incidence in type 1 vs. 2

A

1- 12 to 15 years of age. type 2- 50 to 70 years of age

22
Q

diabetic retinopathy more of a risk factor in in type 1 or 2

A

type 1

23
Q

screening of retinopathy and nephorapthy in diabetic patient

A

in type 1- referral within 4 years of diagnosis, and yearly thereafter. type 2 DM- referral at time of diagnosis, and yearly after

24
Q

ocular complications in diabetics

A

retinal detachment, vitreous hemorrhage, cataracts, glaucoma

25
Q

stages of disease in diabetic nephorpathy

A

hyperfiltration, microalbuminurea, macroalbuminurea, decreasing GFR, end stage renal disease

26
Q

diagnosis of diabetic nephorapthy

A

early morning spot urine albumin/creatinine ratio, check for microscopic hematuria. may also see decreased GFR and elevated BUN/creatinine

27
Q

earliest clinical finding of diabetic nephoraphy

A

urinary protein excretion

28
Q

macrovascular complications in diabetes mellitus

A

coronary heart disease- BP assessment (every visit) and control, lipid screening (annually) and control, smoking cessation