DVTs and PEs Flashcards
Most common EKG abnormality for PE (pulmonary emboli)?
Sinus Tachycardia
Over 90% of acute PE cases are due to what?
Emboli originating from lower extremity DVTs
What is Virchow’s Triad?
- Vessel wall injury
- Hyper-coagulability
- Venous stasis
2 most common hypercoagulable states as risk factors for VTE (venous thromboembolism)
- Factor V Leiden mutation
- Prothrombin gene mutation
3 things which cause DVT in extremities
- injury
- stasis
- prothrombotic status
Common vessel of DVT in leg
Femoral Vein (previously superficial femoral vein)
If a DVT and PE occur simultaneously, which one is symptomatic and which is asymptomatic?
Symptomatic DVT
Asymptomatic PE
What syndrome occurs if DVT is untreated?
Post-thrombophlebitic syndrome
What is a common risk factor that causes UE DVT?
Catheter placement
What is a useful scoring system for DVT if there is no quick US available?
Wells Criteria
- What lab test is helpful if NEGATIVE for diagnosing DVT?
- Sensitivity of 97%
- Specificity of 45%
D-dimer
(endogenous fibrinolysis almost always causes the release of D-dimers from fibrin clot in presence of DVT/PE)
4 causes of elevated D-dimer
- Venous thromboembolic diseaes (DVT / PE)
- Post operative state
- Malignancy
- Normal pregnancy
- Test of choice for DVT?
- Test no commonly used?
- Compression US (veins should normally collapse, but will not collapse if DVT is there)
- Contrast venography
What is our main reason for treating DVT?
(ON EXAM)
Prevent PE
3 timing classifications of PE
- Acute - (24 to 48 hrs)
- Subacute - (days to weeks)
- Chronic (months to years)
PE associated w/ SBP <90 or drop in SBP of greater than 40 for over 15 minutes
Massive PE