DULOXETINE (CYMBALTA) Flashcards
What is the primary use of Duloxetine (Cymbalta)?
Duloxetine is primarily used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain.
True or False: Duloxetine is an SSRI.
False. Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI).
What receptors does Duloxetine primarily target?
Duloxetine primarily targets serotonin and norepinephrine receptors.
Fill in the blank: Duloxetine increases the levels of __________ in the synaptic cleft.
serotonin and norepinephrine
What is the mechanism of action of Duloxetine?
Duloxetine works by inhibiting the reuptake of serotonin and norepinephrine, increasing their availability in the brain.
List one common adverse effect of Duloxetine.
Common adverse effects include nausea, dry mouth, and fatigue.
Multiple choice: Which of the following is NOT a potential side effect of Duloxetine? A) Dizziness B) Weight gain C) Insomnia D) Constipation
B) Weight gain
True or False: Duloxetine can be used to treat chronic pain conditions.
True.
What physiological system does Duloxetine primarily affect?
Duloxetine primarily affects the central nervous system.
Fill in the blank: Duloxetine is indicated for both __________ and __________ pain.
neuropathic and musculoskeletal
What should be monitored in patients taking Duloxetine?
Patients should be monitored for signs of serotonin syndrome and changes in blood pressure.
True or False: Duloxetine has a risk of dependence.
False. Duloxetine is not considered to have a high potential for dependence, but withdrawal symptoms may occur.
Multiple choice: Which of the following conditions is Duloxetine NOT typically prescribed for? A) Generalized anxiety disorder B) Diabetes C) Fibromyalgia D) Major depressive disorder
B) Diabetes
What is the effect of Duloxetine on anxiety symptoms?
Duloxetine can help reduce anxiety symptoms by increasing serotonin and norepinephrine levels.
Fill in the blank: Patients taking Duloxetine should be advised to avoid ________ due to potential drug interactions.
alcohol
