Duiretics Flashcards
which diuretics cause potassium loss (2)
thiazide like and loop
greater risk with thiazide
potassium loss caused by diuretics is a particular problem in patients also taking
cardiac glycocisdes (and those with CVD)
why is hypokalaemia caused by diuretics a particuluar problem in liver disease
may percipitate encephalopathy
what is in co-amilozide
amiloride (k sparing)
and
hydrocholthiazide (thiazide like)
which thiazide like diuretics are now preferred for treatment of hypertension
indapamide chlortalidone (may be given on alt days to control odema)
what conditions might be exacerbated by loop diuretics (3)
diabetes (but hypergylcaemia is more likely with thiazide like)
gout
urinary retention in enlarged prostate
what class is furosemide
loop
what class is bumetanide
loop
what class is indapmide
thiazide like
how long do duitretic actions of bumetanide and furosemide last
up to 6 hours - so can be BD
what class is amiloride
K sparing
K sparing diuretics must not be given with
k supplements (neither should aldosterone antagonists)
what class is spironolactone
aldosterone antagonists (which means it is also K sparing)
what are first and second line diuretics to be used in cirrhosis of the liver
spironolactone and then furosemide
what class is manitol
osmotic - used for cerbral oedema and raised intraoccular pressure
acetazolamide is what type of drug..
carbonic anhydrase inhibitor (used for altitude sickness) - weak diuretic effect
what are the affects of thiazide like diuretics on elctrolytes and uric acid and glucose
all do down except calcium goes up
uric acid and glucose go up
what are the affects of loop diuretics on elctrolytes and uric acid and glucose
all do down
uric acid and glucose (not as much as thiazides) go up
what are the affects of K sparinge diuretics on elctrolytes (1)
k goes up
what are the affects of aldosterone antagonists diuretics on elctrolytes (3)
k goes up
na goes down
uric acid goes up
