Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MED234 Respiratory > Dubin Interstital Lung Disease > Flashcards

Dubin Interstital Lung Disease Flashcards

1
Q

Acute interstitial Pneumonia v. Idiopathic interstitial Fibrosis

A

Acute - fast onset (within 7 days)

Idiopathic - progression over a year

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

50yo with increasing DOE over the past year. Clubbing CXR shows diffuse linear opacities. HRCT shows bilateral abnormalities. Abn PFTs.

A

Idiopathic interstitial Fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

50yo with acute dyspnea. 7 days of dry cough, SOB, fever, malaise. ABG: pH7.30, PaCO2 65, PaO2 55 on 100% O2. CXR - ground glass, septal thickening.

A

Acute interstitial Pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pathogenesis of Drug Induced Pulmonary Injury - name of injury.

A
  • AMIODARONE results in Acute Interstitial Pneumonitis (also, Organizing Pneumonia, ARDS, Hypersensitivity pneumonia)
  • Methotrexate results in interstitial fibrosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Lipid-laden foamy alveolar macrophages are caused by what @ what dose?

A

Amiodarone, (over 400mg/day)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Loosely formed, noncaseating epithelioid cell granulomas in interstitium indicative of what?

A

Hypersensitivity pneumonitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

CXR - (centrilobular) focal patchy consolidation or diffuse ground glass appearance

A

Acute hypersensitivity pneumonitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Dx and pathogenesis:

Pet shop owner has EPISODIC (every 4wks for past 6mo) coughing attacks, SOB, recurrent fever.

A

Hypersensitivity pneumonitis: Bird Fancier’s Lung - IgG mediated hypersensitivity due to exposure to feathers and bird droppings.
- episodic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

PFTs in Hypersensitivity pneumonitis

A

FEV1/FVC increased

FVC reduced

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

35yo dairy farmer, never smoked, presents with wheezing, mild decrease in FEV1, decreased FVC. CXR normal. Labs reveal eosinophilia and clusters of eosinophils in sputum.

A

Bronchial asthma - IgE and eosinophilia.

- NOT episodic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

22yo sheep and turkey farmer. Episodic periods of wheezing, dyspnea, low grade fever of 100F. Serum precipitans with fungus.

A

Hypersensitivity Pneumonitis: Farmer’s Lung - IgE and IgG, Type 3
- episodic, fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What do serum precipitans indicate?

A

Type 3 hypersensitivity reaction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Thermophilic actinomycetes, think what?

A

Farmer’s lung

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Bilateral infiltrates, think what?

A

Farmer’s lung

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Describe Silo Filler’s lung

A

Respiratory distress due to nitric oxide in grain filled silos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

SANDBLASTER, foundry worker, granite worker

A

Silicosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

CXR: bilateral Eggshell calcifications.

In what regions?

A

Silicosis - in hilar and mediastinal regions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

75yoM with severe dyspnea for a year. No weightloss, chest pain, cough, or hemoptysis. 50 pack year hx. Foundry worker.
Always do what after this diagnosis? Why?

A

Silicosis

- ALWAYS administer PPD test because TB is increased by 30(?) in silicosis pts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is a postive PPD test in silicosis pt?

A

10+mm

TB is increased by

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

35yoM with PMG of RA. Treated with gold injections, methotrexate, and aspirin. CXR shows multiple calcified pulmonary nodules in both lungs. Dx?

A

Caplan’s Syndrome = RA + smooth pulmonary nodules.

21
Q

CXR: Localized pleural fibrous plaques/opacities

A

asbestosis

22
Q

ferruginous bodies, mesothelioma

A

asbestosis

23
Q

Occupation: autofactory worker, house builder, shipyard worker

A

asbestosis

24
Q

47yo roofer and wife of roofer with a 30 pack year hx. Chronic, non-productive cough, DOE. CXR shows thickened, calcified opacities in lateral chest wall and under diaphragm. Clubbing

A

Asbestosis - can be secondary!

25
Q

Describe ferruginous bodies

A

Brown fusiform rods with translucent center with iron-containing material.

26
Q

CXR: pleural thickening and possible pleural effusion in a shipyard worker who smokes.

A

Malignant mesothelioma

27
Q

Coalescence of particles containing macules that form discrete areas of interstitial fibrosis, causing distention of resp bronchioles, forming areas of emphysema.

A

Coal Worker’s Pneumoconiosis

28
Q

Prolonged expiratory phase and miner occupation.

A

Coal Worker’s Pneumoconiosis

29
Q

Nuclear technician moved to Fort Worth. 35yo DOE, dry cough, anorexia, night sweats. Bilateral lymphadenopathy. Sarcoidosis, but no anergy, no elevated ACE, so look for what with what test?

A

Berylliosis with beryllium lyphocyte proliferation test.

30
Q

anti-glomerular basement membrane

A

Goodpastures

31
Q

Symptoms in Goodpastures

A

Hemoptysis, hematuria.
Fibrosis secondary to anti-GBM
- NO URT problems

32
Q

Two alveolar filling disorders.

A

Goodpastures, Chronic Eosinophilic Pneumonia

33
Q

Systemic necrotizing granulomatous inflammation in URT as chronic rhinitis or sinusistis, gingival hyperplasia, or serous otitis media.
CXR: multiple nodular or cavitating infiltrates or ulcerative lesions

A

Wegner’s

34
Q

Three important Wegner’s associations.

A
  1. C-ANCA
  2. Hematuria
  3. Upper respiratory problem (*differentiates from Goodpastures)
35
Q

P-ANCA

A

Churg Strauss

36
Q

Necrotizing vasculitis in URT and LRT, preceded by allergic disorders.
- abdominal pain

A

Churg Strauss

37
Q

Three phases of Churg Strauss

A
  1. Allergic stage - Frequent allergic rhinitis/sinusitis
  2. Eosinophilc Stage - Asthma and IgE
  3. Vasculitic Syndrome - erythematous maculopapules
38
Q

CXR: bilateral patchy infiltrates

A

Churg Strauss

39
Q

Kevim, serum Ca, serum ACE tests for what?

A

Sarcoidosis

40
Q

Associations of sarcoidosis.

A
  • Elevated ACE
  • Hypercalciuria, hypercalcemia
  • Anergy
  • Erythema Nodosum
  • Noncaseating granulomas
  • Bilateral hilar lymphadenoapthy (HRCT=possibly see fibrosis or alveolitis)
  • Decreaed DLCO
41
Q

Treatment for sarcoidosis

A
  • Short term, high dose steroids (but NOT INHALED) - sarcoidosis is a systemic disease
42
Q

transbronchial lymphoid biopsy used for what?

A

Sarcoidosis

43
Q

Quantiferron Gold test used for what?

A

Immigrants who have received TB vaccine with positive PPD, to determine if they actually need TB therapy.

44
Q

Acute form of Sarcoidosis is called what and what are the three acute presentations?

A

Lofgren Syndrome:

  1. Hilar adenopathy
  2. Erythema Nodosum
  3. Arthritis (men); fever (women)
45
Q

What four things comprise of Heerfodt’s syndrome?

A

Unveoparotid fever -

  1. Uveitis
  2. Parotid gland involvement
  3. Fever
  4. Possible facial nerve
46
Q

Differential for cavitary lung lesions.

A 
CAVITY:
Carcinoma - squamous cell, melanoma, cervical, sarcoma metastasis
Autoimmune - Wegner's, Rheumatoid Lung
Vascular - bland/septic emboli
Infection - TB, fungal, bacterial
Trauma
Young
47
Q

68yoM with SOB increasing for 2 years. PMH includes psoriasis, taking methotrexate to treat. PFT’s reduced, FEV1/FVC 95+%.

A

Methotrexate induced interstital fibrosis

48
Q

JVD, murmur increases with inspiration, pulse ox reveals desat with exercise. V/Q normal. 22yo.
What is this and what tx?

A

Primary pulmonary HTN.

R-hearted catheter

49
Q

Obese person, falls asleep easily throughout the day, has obstructive sleep apnea.

A

Pickwickian Syndrome

MED234 Respiratory (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions