DSM-5 TR Disorders Flashcards
What are the 3 Intellectual Disability criteria?
1) Intellectual deficit confirmed by assessment
2) Deficits in adaptive functioning that result in a failure of independence and social responsibility and impair functioning across multiple environments in 1+ ADL
3) Onset during developmental period
What is the Intellectual Disability specifier?
Severity - Mild, moderate, severe, and profound based on adaptive functioning
What are the early indicators for Intellectual Disability?
1) Motor delays
2) Poor eye contact during feeding
3) Lack of interest in environmental stimuli (e.g., voices, movement)
What are the 3 domains of adaptive functioning for Intellectual Disabilities?
1) Conceptual (e.g., academics)
2) Social (e.g., making friends)
3) Practical (e.g., transportation)
What are the 6 common Intellectual Disability etiologies?
1) 5% hereditary (Tay-Sachs, fragile X syndrome, PKU)
2) 5% acquired medical condition
3) 10% pregnancy and perinatal problems
4) 15-20% environmental factors (neglect)
5) 30% chromosomal and prenatal toxins (Down Syndrome, fetal alcohol disorder)
6) 30% unknown cause
What are the 5 Intellectual Disability differentials?
1) Neurocognitive disorder
2) Communication disorders
3) SLD
4) ASD
5) Borderline intellectual functioning
What are the Childhood-Onset Fluency Disorder criteria?
Disturbance in normal fluency and time patterning of speech
What is the typical age of onset for Childhood-Onset Fluency Disorder?
Ages 2-7
What is the prognosis for Childhood-Onset Fluency Disorder and what is a good predictor of the prognosis?
1) 65-85% of children recover
2) Severity at age 8 is a good predictor of prognosis
What are the Childhood-Onset Fluency Disorder differentials?
Normal early childhood speech problems
How is Childhood-Onset Fluency Disorder treated?
1) Young children: Reduce stress at home (limit criticism, reduce demands, increase coping skills)
2) Older individuals: Habit reversal training (awareness, relaxation, motivation, competing response, and generalization training)
What are the 4 ASD criteria?
1) Deficits in social communication/interaction across contexts
2) Restricted, repetitive bx, interests, or activities by 2+ symptoms
3) Onset during developmental period
4) Impairs functioning
What is the ASD specifier?
Severity:
1) Level 1 (support)
2) Level 2 (substantial support)
3) Level 3 (very substantial support)
What are the 5 additional features of ASD?
1) Intellectual impairments
2) Language abnormalities
3) Uneven cognitive profiles
4) Motor deficits
5) Self injurious behavior
What are the early warning signs of ASD and the prognosis?
1) Early signs: Abnormal social orienting and responsivity (social gaze, eye contact, joint attention) that are apparent by age 1
2) Only 1/3 adults achieve partial independence
What are 3 factors associated with a better prognosis for ASD?
1) Verbal by age 5/6
2) IQ over 70
3) Later age of onset
What are the 3 etiological factors for ASD?
1) Unusually rapid head growth during 1st year of life
2) Structural brain abnormalities (amygdala, cerebellum)
3) Abnormalities with serotonin, dopamine, and other neurotransmitters
What are the 7 ASD differentials?
1) Rett syndrome
2) Selective mutism
3) Language disorder
4) ID
5) Stereotypic movement disorder
6) ADHD
7) Schizophrenia
What are the 4 treatments for ASD?
1) Parent management training
2) Special education
3) Training in self-care and supported employment
4) Behavioral techniques - shaping and discrimination training
What are the 5 ADHD criteria?
1) 6+ sxs for children and 5+ for ages 17+
2) Pattern of inattentive, hyperactive, or impulsive bx
3) Duration 6+ months
4) Symptoms 2+ context
5) Symptom onset prior to age 12
How long do ADHD symptoms need to be present?
6+ months
When do ADHD symptoms need to start?
Prior to age 12
What are the 3 ADHD specifiers?
1) Predominantly inattentive,
2) Predominantly hyperactive/impulsive
3) Combined presentation
What are the 5 additional features for ADHD?
1) Avg or above avg IQ but lower scores on IQ tests
2) Academic difficulties
3) Social problems
4) Low self-esteem
5) Poorer health, educational, and occupational outcomes
What 7 disorders are individuals with ADHD at risk for?
1) Depression
2) Bipolar
3) Anxiety disorders
4) Antisocial behavior
5) CD
6) ODD
7) SLD
What is the typical course and prognosis for ADHD (4)?
1) 65% - 80% of children continue to meet criteria as adolescents
2) 15% of children continue to meet criteria as young adults
3) 60% eventually meet criteria for partial remission
4) Symptoms vary over lifespan with gross motor activity declining/evolving over time
What are the ADHD prevalence rates and differences by age and gender?
1) Prevalence 5% for children
2) Prevalence 2.5% for adults
2) More prevalent in males (2:1 children, 1.6:1 adults)
3) Combined more common in males, inattentive in females
What are the etiological brain findings for ADHD?
Smaller and less active caudate nucleus, globus pallidus, and prefrontal cortex
What are the 2 etiological theories for ADHD?
1) Barkley’s behavioral disinhibition hypothesis suggests ADHD is due to inability to fit bx to situational demands
2) Another theory suggests an inability to regulate attention
What are the 9 differentials for ADHD?
1) ODD
2) CD
3) Intermittent explosive disorder
4) SLD
5) ID
6) ASD
7) Anxiety disorders
8) Mood disorders
9) Substance use disorders
What are the typical ADHD treatments?
1) CNS stimulants reduce core symptoms 75% of cases
2) Parent/teacher management training
What did the ADHD Mental Health Multimodal Treatment study find?
1) Medication only and combined treatment performed similarly at symptom reduction
2) Combined treatment was superior in other ways
3) But long-term the treatment groups were indistinguishable from the control groups
What are the Cluster A Personality Disorders?
Cluster A (Odd & Eccentric) - Paranoid, Schizoid, Schizotypal
What are the Cluster B Personality Disorders?
Cluster B (Dramatic, Emotional, Erratic) - Antisocial, Borderline, Histrionic, Narcissistic
What are the Cluster C Personality Disorders?
Cluster C (Anxious & Fearful) - Avoidant, Dependent, OCPD
What are the 8 Paranoid PD criteria?
Pervasive distrust and suspiciousness of malevolence as evidenced by 4+ sxs:
1) Suspects malevolence w/o proof
2) Unjustified doubts
3) Reluctance to confide in others
4) Misperceives benign events
5) Holds grudges
6) Misperceives attacks on character
7) Reactive anger
8) Suspects fidelity w/o justification
What are the 7 Schizoid PD criteria?
Pervasive pattern of social detachment and restricted range of emotional expression in social settings and 4+ sxs:
1) Doesn’t desire/enjoy close relationships
2) Prefers solitary activities
3) Little interest in sex
4) Anhedonia
5) Lacks close friends besides relatives
6) Seems indifferent to others’ opinions
7) Emotionally cold/detached
What are the 11 Schizotypal PD criteria?
Pervasive social and interpersonal deficits, discomfort or limited capacity for close relationships, and eccentric cognition, perception, or bx and 5+ sxs:
1) Ideas of reference
2) Odd beliefs
3) Odd perceptions
4) Odd thinking/speaking
5) Peculiar bx or appearance
6) Magical thinking
7) Bodily illusions
8) Suspicious or paranoid, odd affect
9) Lacks close friends other than relatives
10) Excessive social anxiety
11) Desire for close friends but has few and paradoxically prefers being alone
What are Personality Disorders in general?
Patterns of inner experience and bx that:
1) Deviate from cultural norms
2) Are pervasive and inflexible
3) Are stable over time
4) Cause distress or impairment
What are the 8 Antisocial PD criteria?
Disregard/violation of others’ rights and needs history of CD before 15 but cannot be diagnosed before 18 and 3+ symptoms:
1) Nonconformity to social norms or laws
2) Deceitfulness
3) Impulsivity
4) Irritability
5) Aggressiveness
6) Recklessness
7) Irresponsibility
8) Lack of remorse
What are the 3 additional features of Antisocial PD?
1) Inflated self-esteem/grandiosity
2) Lack of empathy
3) Superficial charm
What are the 2 universal diagnostic criteria for Personality Disorders?
1) Onset is in adolescence or early adulthood
2) People under 18 must have had symptoms for at least 1 year
- Except Antisocial PD which cannot be diagnosed until 18+
What are the 9 Borderline PD critiera?
Pattern of unstable relationships, self-image, and affect paired with impulsivity across context. Must have 5+ sxs:
1) Frantic efforts to avoid abandonment
2) Relationships characterized by idealization and devaluation
3) Identity disturbance
4) Risky impulsivity in 2+ ways
5) Recurrent suicidality
6) Affective instability
7) Chronic feelings of emptiness
8) Anger dysregulation
9) Transient paranoia or dissociation
When is Borderline PD usually diagnosed?
Ages 19-34
When are Borderline PD symptoms most severe and how do they change over the life span?
1) Young adulthood
2) Substantial improvement by age 40 with 75% no longer meeting criteria
What is the pattern of symptom improvement for Borderline PD?
Symptom improvement best to worst:
1) Impulsivity
2) Cognitive/interpersonal problems
3) Affect
What is Stern’s Borderline PD etiological theory?
Stern related BPD to narcissism and disturbances in early mother-child attachment
What is Mahler’s Borderline PD etiological theory?
Mahler attributed PDs to fixation at the rapprochement phase of separation-individuation resulting in need for separation paired with fear of abandonment
What is Kernberg’s Borderline PD etiological theory?
Kernberg traced BPD to adverse, unpredictable caregiving that vacillate between rejection and smothering. This produces an insecure ego that tends to engage in “splitting” or the dichotomization of self and others into good vs bad
What is Linehan’s Borderline PD etiological theory?
Linehan’s biosocial model says BPD is caused by emotion dysregulation and vulnerability paired with an invalidating environment
What is the typical treatment for Borderline PD and what are its 2 components and 3 associated outcomes?
DBT and it reduces premature termination, hospitalizations, and parasuicidality. DBT involves:
1) CBT combined with Rogerian acceptance being necessary to change
2) Group skills training, individual outpatient therapy, and telephone coaching
What are the 8 Histrionic PD criteria?
Intense emotionality and attention-seeking and 5+ sxs:
1) Discomfort not being the center of attention
2) Inappropriate seduction
3) Rapidly shifting/shallow emotions
4) Use of appearance to gain attention
5) Excessively impressionistic speech
6) Exaggerated expression of emotion
7) Easily influenced
8) Considers relationships to be more intimate than they are
What are the 10 Narcissistic PD criteria?
Pervasive grandiosity, need for admiration, and lack of empathy and 5+ sxs:
1) Grandiosity
2) Preoccupation with grandiose fantasies
3) Belief in uniqueness and can only be understood by high-status people
4) Requires excessive admiration
5) Sense of entitlement
6) Interpersonally exploitative
7) Lacks empathy
8) Often envious
9) Believes others are envious of them
10) Arrogance
For schizophrenia, what 3 factors are associated with a better prognosis?
1) Female gender
2) Later onset
3) More positive symptoms (which are more responsive to pharmacological treatment)
What are the 3 levels of severity for Substance Use Disorders?
The 3 levels of severity are based on the number of symptoms:
1) Mild = 2 - 3 symptoms
2) Moderate = 4 - 5 symptoms
3) Severe = 6+ symptoms
What are the 3 criteria for Specific Learning Disorder?
1) Difficulty with 1+ academic skill
2) Difficulty persists 6+ months
3) Targeted interventions do not help
What 5 features are associated with a Specific Learning Disorder?
1) An average or better IQ
2) Delays in language development
3) Delays in motor development
4) Difficulty with attention and memory
5) Low self-esteem
What 3 bx or outcomes are individuals with Specific Learning Disorder at-risk for?
1) Antisocial behavior
2) Arrests
3) Convictions
What is SLD’s comorbidity rate with ADHD?
20 - 30%
What is the typical course and prognosis for Specific Learning Disorder?
1) Persistent learning difficulties throughout lifespan
2) 33% of children with reading disorders develop psychosocial problems as adults
What are the gender differences for Specific Learning Disorder?
A SLD is more common in males than in females (estimated ratio 2:1 to 3:1)
What are the 3 etiologies for SLD?
1) Cerebellar-vestibular dysfunction (due to otitis media - ear infections)
2) Incomplete dominance and other hemispheric abnormalities
3) Exposure to toxins (especially lead)
What is dyslexia?
1) A deficit in phonological processing
2) An etiology for SLD
What are the 3 criteria for Tourette’s disorder?
1) Presence of 1+ vocal tic AND multiple motor tics
2) Tics persist for 1+ year
3) Tics began prior to age 18
When is Provisional Tic Disorder diagnosed instead of Tourette’s or Persistent Motor/Vocal Tic Disorder?
Provisional Tic Disorder is diagnosed with there is 1+ motor OR vocal tic that began before age 18 but has been present for LESS than 1 year
When is Persistent Motor or Vocal Tic Disorder diagnosed instead of Tourette’s?
Persistent Motor or Vocal Tic Disorder is diagnosed with there is only 1+ motor OR vocal tic that has been present for 1+ year and began prior to age 18.
What are the 5 additional features of Tourette’s disorder?
1) Obsessions and compulsions (higher rates for biological relatives too)
2) Hyperactivity
3) Impulsivity
4) Distractibility
5) High rates of school problems
What is the prognosis for Tourette’s disorder?
Frequency, severity, and disruptiveness of symptoms tend to decline with age
What is the etiology of Tourette’s disorder?
1) Elevated levels of dopamine
2) Super sensitive dopamine receptors in the caudate nucleus
How can Tourette’s and related disorders be treated (4 treatments)?
1) Antipsychotics (haloperidol, pimozide) are effective in 80% of cases
2) SSRIs can help alleviate the obsessive-compulsive symptoms
3) Clonidine (hypertension med) or desipramine (an antidepressant) can treat hyperactivity and inattention
4) Comprehensive behavioral intervention for tics (CBIT)
What are the 3 diagnostic criteria for Delusional Disorder?
1) Presence of 1+ delusions
2) Delusion(s) last 1+ month
3) Psychosocial functioning is not markedly impaired or any impairment is directly related to the delusions (e.g., a person loses his job because he’s afraid to leave the house and repeatedly misses work)
What are the 7 types of delusions?
1) Erotomanic (love)
2) Grandiose (importance)
3) Jealous (infidelity)
4) Persecutory (persecution)
5) Somatic (abnormal bodily functions or sensations)
6) Mixed
7) Unspecified
What are the 2 specifiers for Delusional Disorder?
1) If delusions are bizarre
2) To describe the disorder’s course (first episode, currently in acute episode)
What are the 3 diagnostic criteria for Schizophrenia?
1) Presence of 2+ active phase symptoms that last 1+ month with 1+ being delusions, hallucination, or disorganized speech (so you can’t just be blunted and disheveled)
2) Signs of the disorder for at least 6+ months
3) Causes distress or impairment
What are the 5 active phase symptoms associated with Schizophrenia?
1) Delusions*
2) Hallucinations*
3) Disorganized speech*
4) Grossly disorganized behavior
5) Negative symptoms
What are the 2 specifiers for Schizophrenia?
1) Course
2) Catatonia
What are the 6 associated features of Schizophrenia?
1) Inappropriate affect (e.g., laughing for no reason)
2) Dysphoric mood
3) Disturbed sleep
4) Lack of interest in eating
5) Anosognosia
6) Substance Use Disorder (particularly Tobacco Use Disorder)
What are the prevalence rates for Schizophrenia and differences by gender?
1) Lifetime prevalence of Schizophrenia ranges from 0.3 to 0.7%
2) Prevalence rate is slightly lower for females than for males
What were the 3 results of the World Health Organization’s International Pilot Study of Schizophrenia?
The WHO study found that patients from developing countries compared to developed countries were more likely to exhibit:
1) An acute onset of symptoms
2) A shorter clinical course
3) Complete remission of symptoms
What is the typical course and prognosis for Schizophrenia?
1) Onset of Schizophrenia is usually between the late teens and early 30s
2) Peak age of onset being in the early to mid-20s for males and the late 20s for females
3) Course is ordinarily chronic with complete remission being rare
What 8 factors are associated with a better prognosis for Schizophrenia?
1) Good premorbid adjustment
2) An acute/later onset
3) Female gender
4) A precipitating event
5) A brief duration of active-phase symptoms
6) Insight into the illness
7) A family history of a mood disorder
8) No family history of Schizophrenia
What is the concordance data for Schizophrenia?
1) High risk among first-degree biological relatives
2) Biological siblings 10%
3) Fraternal twins 17%
4) Child of 2 parents with schizophrenia 46%
5) Identical twins 48%
What are the 8 etiologies for Schizophrenia?
1) Enlarged ventricles
2) Smaller hippocampus
3) Smaller amygdala
4) Smaller globus pallidus
5) Hypofrontality (e.g., lower prefrontal cortex activity)
6) Dopamine hypothesis (e.g., elevated dopamine or oversensitive dopamine receptors)
7) Imbalance of serotonin, glutamate, and GABA
8) Prenatal exposure to an influenza virus during winter
What are the 5 differentials for Schizophrenia?
1) Amphetamines and cocaine
2) Schizoaffective Disorder
3) Major Depressive Disorder
4) Bipolar
5) Autism
In Schizophrenia, mood symptoms are brief, do not occur during the active phase, and do not meet the full criteria for a mood episode.
How can you differentiate Mood Disorders with psychotic features from Schizoaffective Disorder?
Schizoaffective disorder would be diagnosed instead of a mood disorder if there was a period of 2+ weeks without prominent mood symptoms
How can you differentiate Mood Disorders with psychotic features from Schizophrenia?
Schizophrenia is not diagnosed when the psychotic symptoms only occur during episodes of mood disturbances (e.g., depressive or manic episode)
What are the 7 treatments for Schizophrenia?
1) Traditional antipsychotics (haloperidol, fluphenazine)
2) Atypical antipsychotics (clozapine, risperidone)
3) Individual CBT
4) Psychoeducation
5) Social skills training
6) Supported employment
7) Family-based interventions especially with high EE families (e.g., families who are hostile or overinvolved emotionally)
What are the 2 diagnostic criteria for Schizophreniform Disorder?
1) Presence of 2+ active phase symptoms
2) Symptoms persist 1-6 months
*The criteria are essentially identical to those for Schizophrenia except that the disturbance is present for at least one month but less than six months and impairment may occur but is not required.
What is the prognosis for Schizophreniform Disorder?
66% eventually meet criteria for Schizophrenia or Schizoaffective Disorder
What are the 4 diagnostic criteria for Brief Psychotic Disorder?
1) Presence of 1+ symptoms (delusions, hallucinations, disorganized speech, or grossly disorganized or catatonic behavior) with 1+ being delusions, hallucinations, or disorganized speech
2) Symptoms persist 1-30 days
3) Eventual return to premorbid functioning
4) Onset usually follows exposure to an overwhelming stressor
What are the 3 diagnostic criteria for Schizoaffective Disorder?
Concurrent symptoms of:
1) Schizophrenia
2) Major depression or mania
3) A period of 2+ weeks without prominent mood symptoms
What are the 4 diagnostic criteria for Bipolar 1?
1) Occurrence of 1+ manic episode
2) Mania must last 1+ one week with sxs being present most of the day, nearly every day
3) Mania must include 3+ characteristic sxs – e.g., grandiosity, decreased need for sleep, excessive talkativeness, or flight of ideas
4) Dx requires impairment, hospitalization, or psychotic features
What are the 3 specifiers for Bipolar 1?
1) Severity (mild, moderate, or severe) based on number of symptoms
2) Type of most recent episode (manic, hypomanic, depressed, or unspecified)
3) Pattern (e.g., rapid cycling, mood-congruent psychotic features, mood-incongruent psychotic features, peripartum onset, seasonal pattern)
What are the 5 patterns for Bipolar 1?
1) Rapid cycling
2) Mood-congruent psychotic features
3) Mood-incongruent psychotic features
4) Peripartum onset
5) Seasonal pattern
What are the 3 associated features of Bipolar Disorder?
1) Anxiety disorders
2) Substance use disorders
3) Lifetime risk for completed suicide is about 15x higher than the general population
What are the prevalence rates for Bipolar 1 and differences by gender?
1) 12-month prevalence for Bipolar I Disorder in the United States is 0.6%
2) Lifetime male-to-female prevalence ratio is approximately 1.1 : 1
What is the typical course for Bipolar 1?
1) Average age of first episode is 18 years old
2) 90% of individuals who have one episode experience additional episodes
What is the general concordance pattern for Bipolar Disorder?
1) Identical twins - concordance rates ranging from .67 to 1.0
2) Fraternal twins - concordance rates of .20
3) Higher risk for first-degree relatives
- Genetic factors have been most consistently linked to the Bipolar Disorders
What are the 3 best therapy options to treat Bipolar Disorder?
1) Cognitive-behavioral therapy (CBT)
2) Family-focused treatment (FFT)
3) Interpersonal and social rhythm therapy (IPSRT)
What are the 3 basics about prescribing antidepressants for Bipolar 1?
1) Antidepressants may be prescribed to treat depressive symptoms
2) Antidepressant may trigger a manic episode when combined with a mood stabilizer
3) Triggering mania is more likely with TCAs compared to SSRIs
What medication works best for Bipolar with rapid cycling or dysphoric mania?
Anticonvulsants like carbamazepine or divalproex sodium
What medication works best for acute mania?
Antipsychotics like Olanzapine or Risperidone
What is classic Bipolar 1 and what medication works best for it?
Classic Bipolar involves distinct episodes of mania and depression.
Lithium works best for classic Bipolar 1 and is effective in 60 - 90% of cases.
What are the 2 diagnostic criteria for Bipolar 2?
1) Occurrence of 1+ hypomanic episodes that last 4+ consecutive days, and involve 3+ characteristic sxs of mania that don’t cause marked impairment or require hospitalization
2) Occurrence of 1+ major depressive episodes that last 2+ weeks, and involves 5+ characteristics of depression
What are the 5 diagnostic criteria for Cyclothymic Disorder?
1) Numerous periods of hypomanic sxs that don’t meet criteria for a hypomanic episode
2) Numerous periods with depressive sxs that don’t meet criteria for a major depressive episode
3) Causes distress or impairment
4) Symptoms last for 2+ years in adults or 1+ year in youth
5) Symptoms cannot remit for greater than 2+ months at a time
What are the 7 diagnostic criteria for Disruptive Mood Dysregulation Disorder?
1) Severe recurrent temper outbursts that are disproportionate to the situation and atypical for developmental level
2) A persistently irritable or angry mood between outbursts
3) Sxs have persisted for 12+ months
4) Sxs are present in 2+ settings
5) Outbursts occur on average 3+ times per week
6) Dx must be assigned between ages 6 - 18 years
7) Onset must occur before 10 years old
What are the 4 diagnostic criteria for Major Depressive Disorder?
Presence of 5+ sxs nearly every day for at least 2+ weeks with 1+ depressed mood or a loss of interest or pleasure:
1) Changes in weight
2) Changes in appetite
3) Sleep disturbances
4) Psychomotor agitation or retardation
5) Fatigue or loss of energy
6) Feelings of worthlessness or excessive guilt
7) Diminished ability to think or concentrate
8) Recurrent suicidality
9) Causes distress or impairment
What are the 3 specifiers for Major Depressive Disorder?
1) Severity (mild, moderate, severe)
2) Course (single episode or recurrent episode and in partial remission or in full remission)
3) Accompanying features (e.g., with psychotic features, with atypical features, with peripartum onset, with seasonal pattern)
When do you use the specifier peripartum onset?
Peripartum onset is applied to MDD or the Bipolar Disorders when sxs occur during pregnancy or within 4 weeks postpartum
What are the prevalence rates of the 3 peripartum conditions?
1) 10 - 20% experience peripartum depression
2) .1 to .2% develop postpartum psychosis
3) “Baby blues” occurs in 80% of people within 2 weeks of delivery and involve mild mood symptoms
What 3 factors have been associated with Seasonal Affective Disorder?
1) Changes in the dark-light cycle that increases melatonin levels
2) A phase-delay in circadian rhythms
3) Serotonergic dysfunction
What are the 3 peripartum onset Mood Disorder symptoms?
1) Anxiety
2) Preoccupation with the infant’s well-being
3) Delusional thoughts about the infant
When do you use the seasonal pattern onset for Mood Disorders?
The seasonal pattern specifier is applied to MDD and the Bipolar Disorders when the onset of mood episodes are related to particular times of the year