Dry Eyes Flashcards
List the causes of Dry Eye
Increased evaporation
Hyposecretion
Ocular surface disorder
What does the ‘ increased evaporation ‘ in the eye indicate ?
Lipid Layer deficieny
What causes the lipid layer to be deficient ?
MGD - Meibomian Gland Dysfunction
What is the function of the Meibomian Gland ?
Secretes meibum responsible for the formation of the tear film outer layer .
Meibum aids in reducing evaporation of tears
What can cause MGD?
Swollen or blocked MG
How can the MG become blocked?
Overtime from debris caught in eyelid for example from makeup
What can occur after a prolonged Gland blockage ?
Notching
Hyposecretion is linked to which layer ?
Aqueous layer - middle
List the causes of hyposecretion
Age Sjögren’s syndrome Lacrimal gland destruction Scarring Neurological
Explain how age impacts the aqueous layer of the tear film
With age the aqueous layer deteriorates
The aqueous layer is secreted by the lacrimal glands which with increasing age undergo structural and functional alterations
Define Sjögren’s syndrome (showgrins)
Autoimmune disease
A condition that affects part of the body that produce fluids like tears and saliva
Name some symptoms of Sjögren’s syndrome
Dry mouth , eyes , skin
Affects 1-3% of population
Also affect kidney , lungs and blood vessels
What can cause lacrimal gland destruction ?
Thyroid disease
Inflammation
Radiation - leading to cell degeneration
How can scarring affect the lacrimal gland ?
Eg. Surgery may cause obstruction of flow from the gland
What could cause a deficient mucin layer ?
LASIK surgery
Shaves anterior layer of cornea , slices through some corneal nerves causing goblet cells to die away ( atrophy )
Reduces number of functioning goblet cells = reduced mucin layer
Define EMBD
Epithelium membrane basement disorder
EMBD occurs when EBM develops abnormally resulting in folds in the tissue