Druuuuugggss

Question 1

If you are a GP and suspect bacterial meningitis (Group B Neisseria Meningitidis) what should you prescribe and route?
If you are in hospital what would you give?

Answer 1

GP - Benzylpenicillin IM/IV

Hospital - 3rd Generation cephalosporin such as Cefotaxime

Question 2

What drugs do you give for Asthma and in what order?

Answer 2

1 - Short Acting Beta 2 Agonist - Salbutamol
2 - Long Acting Beta 2 Agonist - Salmeterol

Muscarinic Receptor Aconists Short acting: Ipratropium Bromide, Long Acting Tiatropium Bromide

Corticosteroids, inhaled - beclometasone, budesonide. Oral - prednisolone, IV - hydrocordisone

Question 3

What drugs do you give for Rheumatoid Arthritis? What other disease can you treat these with?

Answer 3

Disease Modifying Anti-Rheumatic Drugs - Sulfasalazine, Methotrexate
TNF-Alpha Blockers - Infliximab

Can also use for Inflammatory Bowel Disease

Question 4

Which drug is specifically for ulcerative colitis?

Answer 4

Mesalazine

Question 5

What drugs are given for Parkinsons?

Answer 5

Levodopa - Dopamine precursor
Dopamine Agonists - Ropinirole
MAO-B INhibitors - Rasagiline

Question 6

What drug can help to control spasticity?

Answer 6

Baclofen or Gabapentin

Question 7

What drug is used to treat Systemic Lupus Erythematous?

Answer 7

Hydroxychloroquine, Methotrexate

Question 8

How is acute gout treated?

Answer 8

NSAIDS, then Colchicine

Question 9

How is gout prevented? What is the mechanism

Answer 9

Allopurinol - xanthine oxidase inhibitor

Question 10

How are migraines prevented? How are attacks treated?

Answer 10

Beta Blockers prevent

Oral Triptan treat

Question 11

How is motor neurone disease treated?

Answer 11

Riluzole

Question 12

How is BPH treated?

Answer 12

Alpha Blocker - Tamsulosin

5-alpha reductase inhibitor - Finasteride

Question 13

How are peptic ulcers/ GORD treated?

Answer 13

1. Proton Pump Inhibitors - Omeprazole

2. H2 Receptor Antagonists - Ranitadine

Question 14

How is AF treated?

Answer 14

Class I Na Channel Blocker - Flecainide
Class III K+ Channel Clocker - Amiodarone

Rate Control Vs Rhythm Control - Rate: Beta Blocker/Calcium Channel Blocker -
Rhythm Control : Digoxin, Amiodarone

Question 15

What are some of the side effects of Amiodarone?

Answer 15

Hypothyroidism, Hyperthyroidism, Liver Toxicity, Photophobia, Slate-grey skin, peripheral neuropathy, pneumonitis. Must do frequent TFT’s.

Question 16

How do you treat Bradycardia?

Answer 16

Glucagon if due to a beta blocker OD

Atropine for other causes but contraindicated in patients with heart transplants

Question 17

How do you treat supra ventricular tachycardia?

Answer 17

Adenosine

Question 18

How do you treat various epilepsies?

Answer 18

Focal Seizures: Carbamazapine/Lamotrigine

Generalised Tonic Clonic, Absencew seizures - Sodium Valproate

Question 19

How do you treat Status Epilepticus?

Answer 19

1. Lorazepam/Diazapam

2. Phenytoin Infusion

Question 20

How do you treat stroke?

Answer 20

If Ischaemic - thrombolysis within 4.5 hours - Alteplase - would make Haemorrhagic strokes worse

Question 21

What medications are used for type 2 Diabetes?

Which cause weight gain, which cause weight loss?

Answer 21

1. Metformin - Biguanide
2. Sulfonylureas - Glimepiride (CAUSE WEIGHT GAIN)
3. Piogliatzone (CAUSES WEIGHT GAIN)
4. GLP-1 Agonists - Exanatide, Liraglutaide (PROMOTES WEIGHT LOSS)
5. DPP4-Inhibitors - Linagliptin, sitagliptin