Drugs on the Heart Flashcards
Heart Rhythm Disturbed
Dysrhythmia
Heart temporarily deprived of O2
Angina
Heart deprived of O2
Heart attack
Heart does not pump properly
Heart failure
Preventing Coronary Artery Disease
Change of lifestyle
Reduce BP
Statins to reduce cholesterol
Symptoms of Angina
“Crushing Pain” may radiate to arm, neck, jaw.
Pain results from Cardiac ischemia, reduced O2 supply o tissue - tissue detects the problem.
Angina Solution
Reduce O2 demand (reduce workload) OR increase O2 supply (improve blood flow)
Glyceryl Trinitrate GTN
Treatment for Angina & Heart Attacks
Given as spray or tablet
Dilates peripheral blood vessels
Reducing workload, improving blood flow through coronary arteries.
Atenolol
Treatment for Angina: Beta Blocker
Reduces cardiac movement & O2 demand goes down.
Acts on B1 adrenoceptors
Tissue Plasminogen Activator
Treatment for Heart Attacks
Clot busting drug
Works within a few hours
Angioplasty
Treatment for Heart Attacks
-Reopened blocked vessel using tiny balloon/stent
Propranolol
Treatment for Heart Attack
Reduces workload, improve blood flow, reduce pain
Digoxin
Treatment for Heart Failure
Increases cardiac output & contraction
Pumps sodium out of cell and pumps and pot in
Increases amount of Ca2+ in stores
Treatment for Dysrhythmias
Surgical, Electrical, Drugs
Which drug targets Calcium Channels?
Verapamil